2014 CRS Annual Meeting Abstracts

The CRS Annual Meeting & Exposition offered nearly 750 podium and poster presentations.

Abstracts are available to current members and annual meeting attendees for one year.

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Shortcuts to Podium Session Abstracts

Monday, July 14
Advances in Process Engineering - New Methods for the Production of Particles, Capsules, and Coatings
Innovations in Oral Drug Delivery
Intracellular Delivery of Nucleic Acids and Proteins
Overcoming Biological Barriers
Mini Symposia: Interspecies Clinical Pharmacology Dosing Concepts
Advances in RNA and DNA Delivery
Evaluation and Characterization of Controlled Release Products and Production
Nanoparticle Based Delivery to the Brain
Transdermal Delivery
Mini Symposia: Advancements to Develop and Deliver Biologics

Tuesday, July 15
Advances in Drug Delivery to the Eye
Nanoparticles in Tumor Treatment
Overcoming Barriers in the GI Tract
Predictive Animal Models for Assessing Long-Acting Formulations for Human and Animal Health and Their Challenges
Mini Symposia: Micro- and Nano-Encapsulation: From Innovation to Commercialization
Advances in Drug Delivery to the Lung
Controlled Release Applications in Food, Feed, and Beverages
Innovations in Micro- and Nano-Based Delivery
Proteins, Peptides, and Vaccines
Mini Symposia: Cancer Epigenetics, Epigenetic Drugs and Delivery

Wednesday, July 16
Breakthrough Technologies
Cells as Delivery Vehicles
Controlled Release of Actives in Consumer Products
Novel Development in Formulation, Analytical Chemistry, and Processing in Animal Health and Preclinical Sciences
Mini Symposia: Individualized Medicine and Theranostics

Shortcuts to Poster Sessions

Advances in Drug Delivery to the Eye
Advances in Drug Delivery to the Lung
Advances in Process Engineering - New Methods for the Production of Particles, Capsules, and Coatings
Advances in RNA and DNA Delivery
Breakthrough Technologies
Cells as Delivery Vehicles
Controlled Release Applications in Food, Feed, and Beverages
Controlled Release of Actives in Consumer Products
Evaluation and Characterization of Controlled Release Products and Production Processes
Innovations in Micro- and Nano-Based Delivery
Innovations in Oral Drug Delivery
Intracellular Delivery of Nucleic Acids and Proteins
Nanoparticle-Based Delivery to the Brain
Nanoparticles in Tumor Treatment
Novel Developments in Formulation, Analytical Chemistry, and Processing in Animal Health and Preclinical Sciences
Overcoming Barriers in the GI Tract
Overcoming Biological Barriers
Proteins, Peptides, and Vaccines
Transdermal Delivery



PODIUM SESSIONS

Advances in Process Engineering - New Methods for the Production of Particles, Capsules, and Coatings     [RETURN TO TOP]

1  Invited Speaker: Production of Nano/Micro Drug Particles by Supercritical Fluid Technology. Presenter: Sateesh Sathigari, Patheon Pharmaceuticals, U.S.A. VIEW ABSTRACT

2  The NanoAssemblr™ Platform: Scalable, Microfluidics-based Manufacture of siRNA Lipid Nanoparticles. Presenter: Colin Walsh , Precision NanoSystems Inc., U.S.A.. Authors: C L Walsh, K Ou, A Ansari, T J Leaver, A W Wild, R J Taylor, E Ramsay, P R Cullis. VIEW ABSTRACT

3  Accepting the challenge of scale-up - A new approach for the treatment of colon cancer based on nanoparticles overcomes the limitations of batch size. Presenter: Susanne Beyer , Institute of Pharmaceutical Technology; Goethe University Frankfurt, Germany. Authors: S Beyer. VIEW ABSTRACT

4  Dissolution of Poorly Soluble Drug Nanoparticles from Edible Polymer Stripfilms. Presenter: Rajesh Davé , Chemical Biological and Pharmaceutical Engineering, New Jersey Institute of Technology, U.S.A.. Authors: J Zhang, Z Ma, E Bilgili, R N Davé. VIEW ABSTRACT

5  Designing Sustained Release Encapsulates loaded with Water Soluble Oxidant: Carbamide Peroxide. Presenter: Fideline Tchuenbou-Magaia , University of Birmingham, United Kingdom. Authors: F L Tchuenbou-Magaia, J Gwyer, N Young, Z Zhang. VIEW ABSTRACT

Innovations in Oral Drug Delivery     [RETURN TO TOP]

6  Invited Speaker: Oral delivery of heparin conjugate. Presenter: Youngro Byun , Seoul National Univ, Korea. Authors: Y Byun. VIEW ABSTRACT

7  Synergistic Effect of M Cell Targeting Peptide and Mucoadhesive Vehicle on Induction of Immune Responses in Oral Vaccine Delivery. Presenter: Chong-Su Cho , Seoul National University, South Korea. Authors: C Cho. VIEW ABSTRACT

8  Can ion pairing mediate drug uptake via active carriers?. Presenter: Amr ElShaer , Drug Discovery, Delivery and Patient Care (DDDPC), School of Pharmacy and Chemistry, Kingston University London, Penrhyn Road, Kingston Upon Thames, Surrey, KT1 2EE, UK, United Kingdom. Authors: A ElShaer, A S Rahman, P Hanson, A R Mohammed. VIEW ABSTRACT

9  High-throughput, slit-surface, core-sheath electrospinning: Improving the formulation and dissolution of poorly soluble drugs. Presenter: Quynh Pham , Arsenal Medical, U.S.A.. Authors: Q Pham, E Fan, L Ruiz, J Podyma, R Mulligan, T Freyman. VIEW ABSTRACT

10  Mucus Penetrating Nanoparticles Improve Drug and Gene Delivery to the Gastrointestinal Tract. Presenter: Katharina Maisel , Johns Hopkins University, U.S.A.. Authors: K Maisel, L Ensign, M Reddy, R Cone, J Hanes. VIEW ABSTRACT

Intracellular Delivery of Nucleic Acids and Proteins     [RETURN TO TOP]

11  Invited Speaker: Intracellular Delivery of BIologic Drugs. Presenter: Patrick Stayton , Univ of Washington, U.S.A.. Authors: P Stayton. VIEW ABSTRACT

12  The Multifaceted Role of Glycosaminoglycans in the Cellular Uptake of Cell-Penetrating Peptides. Presenter: Roland Brock , Radboud University Medical Centre, Netherlands. Authors: R Wallbrecher, S Schmidt, W P Verdurmen, P H Bovee-Geurts, F Bröcker, A Reinhardt, T H van Kuppevelt, J Eilander, S Fanghänel, J Bürck, P Wadhwani, P H Seeberger, A S Ulrich, R Brock. VIEW ABSTRACT

13  Nucleodendrimers for endosomal escape. Presenter: Silvia Muro , University of Maryland College Park, U.S.A.. Authors: S Muro. VIEW ABSTRACT

14  Wrapping Polyplex with a Monolayer of Rationally Designed Block Copolymer for Inter- and Intra-cellular Delivery of siRNA. Presenter: Tuo Jin , School of Pharmacy, Shanghai Jiao Tong Univerisity, China. Authors: X Ge, T Jin. VIEW ABSTRACT

15  Attenuation of High Mobility Group Box 1 Release into Extracellular Milieu by TAT-High Mobility Group Box 1 A Fusion Protein Binding in islet cells. Presenter: Dong Yun Lee , Department of Bioengineering, College of Engineering, Hanyang University, 22 Wangshimniro, Seongdong-gu, Korea. Authors: Y Hwang, M Lee, D Lee. VIEW ABSTRACT

Overcoming Biological Barriers     [RETURN TO TOP]

16  Invited Speaker: Overcoming Macrophage Barriers:  'Self' peptides on Nanoparticles, Viruses, and Molecular Therapy. Presenter: Dennis Discher , Univ of Pennsylvania, U.S.A.. Authors: D Discher. VIEW ABSTRACT

17  Bypassing Endocytosis Size-Restrictions. Presenter: Silvia Muro , University of Maryland College Park, U.S.A.. Authors: M Ansar, D Serrano, I Papademetriou, T Bhowmick, S Muro. VIEW ABSTRACT

18  Exploring the Potential of the Tat Cell Penetrating Peptide in Drug Delivery Using Both Drug Conjugation and Self-Assembly Strategies. Presenter: Pengcheng Zhang , The Johns Hopkins University, U.S.A.. Authors: P Zhang, A Cheetham, L Lock, Y Lin, H Cui. VIEW ABSTRACT

19  Design of hypoxically activated prodrug to overcome hypoxic barrier. Presenter: Yutaka Ikeda , University of Tsukuba, Japan. Authors: Y Ikeda, H Hisano, Y Nagasaki. VIEW ABSTRACT

20  Physiology of intrathecal bolus as revealed by quantitative PET studies. Presenter: Mikhail Papisov , Massachusetts General Hospital, Harvard Medical School, and Shriners Hospitals for Children, U.S.A.. Authors: M I Papisov, V Belov, A J Fischman, J Titus, M Gagne, C Gillooly, A Bonab, D Levine. VIEW ABSTRACT

Mini Symposia: Interspecies Clinical Pharmacology Dosing Concepts     [RETURN TO TOP]

21  Invited Speaker: The Biopharmaceutics of Veterinary Drug Delivery. Presenter: Steven (Steev) Sutton , University of New England, U.S.A.. Authors: S C Sutton. VIEW ABSTRACT

22  Invited Speaker: Interspecies Clinical Pharmacology Dosing Concepts Mini Symposia. Presenter: Mark Papich , North Carolina State Univ, U.S.A.. Authors: M G Papich. VIEW ABSTRACT

23  Invited Speaker: Zoological Pharmacology: Of Mice and Elephants. Presenter: Robert Hunter, Parnell. VIEW ABSTRACT

Advances in RNA and DNA Delivery     [RETURN TO TOP]

24  Invited Speaker: Intracellular Signal-Responsive Carriers as New Strategy to Secure Cell Specificity in Tumor Gene Delivery . Presenter: Yoshiki Katayama , Kyushu Univ, Japan. Authors: Y Katayama, C Kim, K Li, G Zhao, Y Nakamura, A Kishimura. VIEW ABSTRACT

25  Suppression of Notch Signaling for Rheumatoid Arthritis Therapy Using Polymerized siRNA/ Thiolated Glycol Chitosan Nanoparticles. Presenter: Min Ju Kim , Korea Institute of Science and Technology (KIST), Korea. Authors: M Kim, J Park, S Lee, D Jo, S Kim, I Kim, I Kwon, K Kim. VIEW ABSTRACT

26  A cationic nanoemulsion for the delivery of next generation RNA vaccines. Presenter: Luis Brito , Novartis Vaccines and Diagnostics, U.S.A.. Authors: L A Brito. VIEW ABSTRACT

27  Versatile Platform for Sustained Gene Silencing Improves Excisional Wound Healing in Diabetic Rats. Presenter: Christopher Nelson , Vanderbilt University, U.S.A.. Authors: C E Nelson, J R Martin, M K Gupta, E J Adolph, F Yu, J M Davidson, S A Guelcher, C L Duvall. VIEW ABSTRACT

28  Lipid nanoparticles for organ-specific delivery of RNA. Presenter: Heinrich Haas , Ribological GmbH, Germany. Authors: H Haas, D Fritz, M Meng, L M Kranz, K C Reuter, M Diken, S Kreiter, S Funari, D Pawlowska, G Brezesinski, U Sahin. VIEW ABSTRACT

Evaluation and Characterization of Controlled Release Products and Production     [RETURN TO TOP]

29  Invited Speaker: An Introduction to Dynamic Imaging Particle Analysis for Use in Controlled Release R&D and Production Environments. Presenter: Lew Brown , Fluid Imaging Technologies, U.S.A.. Authors: L Brown. VIEW ABSTRACT

30  Real time Raman imaging to understand dissolution performance of amorphous solid dispersions. Presenter: Francesco Tres , University of Nottingham, United Kingdom. Authors: F Tres, S A Wren, J W Aylott, J C Burley. VIEW ABSTRACT

31  The influence of  spray drying parameters on particle composition, structure and in vitro release of injectable microspheres for controlled release. Presenter: Joke Meeus , University of Leuven, Belgium. Authors: J Meeus, M Lenaerts, D J Scurr, K Amssoms, M C Davies, C J Roberts, G Van den Mooter. VIEW ABSTRACT

32  Mass Spectrometry for Comprehensive Characterization of Controlled Release Systems. Presenter: Ruth Schmid-Baumberger , SINTEF Materials and Chemistry, Sector Biotechnology and Nanomedicine, Norway. Authors: S F Borgos, A Brunsvik, P Kristiansen, F Männle, Ý Mørch, R Schmid-Baumberger, K Vernstad, K Zahlsen. VIEW ABSTRACT

33  Non-Disruptive Measurement of Encapsulation Efficiency For Hydrophobic Actives. Presenter: Fanwen Zeng , The Dow Chemical Company, U.S.A.. Authors: F Zeng. VIEW ABSTRACT

Nanoparticle Based Delivery to the Brain     [RETURN TO TOP]

34  Invited Speaker: Dendrimer-based targeted systemic therapies for neuroinflammation in CNS disorders. Presenter: Kannan Rangaramanujam , Johns Hopkins Hospital, U.S.A.. Authors: K Rangaramanujam. VIEW ABSTRACT

35  Highly compacted pH-responsive DNA nanoparticles mediate efficient transgene silencing in experimental glioma. Presenter: Anthony Kim , University of Maryland School of Medicine, U.S.A.. Authors: A J Kim, N J Boylan, J Suk, J Hanes, G F Woodworth. VIEW ABSTRACT

38  Mechanism of Nanocarrier Release from the Abluminal Endothelium. Presenter: Rachel Manthe , Fischell Department of Bioengineering, University of Maryland, College Park, U.S.A.. Authors: R L Manthe, S Muro. VIEW ABSTRACT

506  Amino-Functionalized Multi-Walled Carbon Nanotubes: Uptake and Transcytosis across the Blood-Brain Barrier in vitro. Presenter: Houmam Kafa , King's College London, United Kingdom. Authors: H Kafa, N Rubio, J Tzu-Wen Wang, K Venner, E Pach, B Ballesteros, N Abbott, K T Al-Jamal. VIEW ABSTRACT

517  Squalenoyl Adenosine Nanoparticles and Cerebral Ischemia. Presenter: Alice GAUDIN , Institut Galien Paris Sud, France. Authors: A GAUDIN, S LEPETRE, M YEMISCI, O TAGIT, N HILDEBRANDT, K ANDRIEUX, T DALKARA, P COUVREUR. VIEW ABSTRACT

Transdermal Delivery     [RETURN TO TOP]

39  Invited Speaker: Improving The Reach Of Vaccines To The Developing World With Nanopatches. Presenter: Mark Kendall , Univ of Queensland, Australia. Authors: M Kendall. VIEW ABSTRACT

40  Novel coating mechanism for silicon microneedle arrays based upon pH-sensitive electrostatic interactions. Presenter: Joke Bouwstra , Leiden Academic Centre for Drug Research, Netherlands. Authors: K Van der Maaden, H Yu, K Sliedregt, R Leboux, A Kros, W Jiskoot, J Bouwstra. VIEW ABSTRACT

41  Tyrosine-derived Nanospheres (TyroSphereTM): A New Carrier System for Topical Delivery of Adapalene  . Presenter: Tannaz Ramezanli , Ph.D. student, U.S.A.. Authors: T Ramezanli, Z Zhang, J Kohn, B B Michniak-Kohn. VIEW ABSTRACT

42  Transdermal Nanographene Oxide - Hyaluronic Acid Conjugate for Photothermal Ablation Therapy of Skin Cancer. Presenter: Sei Kwang Hahn , POSTECH, South Korea. Authors: S Hahn, H Jung, W Kong, K Kim, S Yun. VIEW ABSTRACT

43  Delivery of recombinant human epidermal growth factor via hair follicles with a nano liposome system. Presenter: Sangkil Lee , Keimyung Univ, Korea. Authors: J Seo, S Jeon, S Lee. VIEW ABSTRACT

Mini Symposia: Advancements to Develop and Deliver Biologics     [RETURN TO TOP]

44  Invited Speaker: Examining the challenges underlying the delivery of therapeutic proteins. Presenter: Stephen Buckley , Novo Nordisk A/S, Denmark. Authors: S T Buckley. VIEW ABSTRACT

45  Invited Speaker: Recent Innovations in Oral Vaccine Delivery. Presenter: Rosie McLaughlin , Catalent Pharma Solutions, United Kingdom. Authors: R T McLaughlin. VIEW ABSTRACT

46  Invited Speaker: Smart PEGylation: Enabling Extended Half-life without Loss of Bioactivity. Presenter: Kang Choon Lee , SungKyunKwan Univ, Korea. Authors: K Lee. VIEW ABSTRACT

Advances in Drug Delivery to the Eye     [RETURN TO TOP]

47  Invited Speaker: Facilitated Drug Delivery to the Retina by Controlled Modulation of Permeability at the Inner Blood-retina Barrier. Presenter: Pete Humphries , Univ of Dublin, Ireland. Authors: M Campbell, P Humphries. VIEW ABSTRACT

48  Ocular delivery of a model biopharmaceutical, lacritin, using protein polymers. Presenter: John MacKay , University of Southern California, U.S.A.. Authors: J A MacKay, W Wang, P Hsueh, M Edman-Woolcott, S F Hamm-Alvarez. VIEW ABSTRACT

49  In vivo enhancement of transscleral penetration of macromolecules by low-intensity and low-frequency ultrasound . Presenter: Wai-leung Suen , The Hong Kong University of Science and Technology, Hong kong. Authors: W L Suen, H Wong, Y Yu, C L Lau, C A Lo, Y Chau. VIEW ABSTRACT

50  Injectable, Degradable and Biocompatible Poly(oligoethylene glycol methacrylate) Hydrogels. Presenter: Todd Hoare , McMaster University, Canada. Authors: E Bakaic, N M Smeets, T Hoare. VIEW ABSTRACT

51  In vivo evaluation of intravitreally injected connexin43 mimetic peptide in reducing retinal ganglion cell loss and vessel leak after retinal ischemia. Presenter: Ilva Rupenthal , Buchanan Ocular Therapeutics Unit, Department of Ophthalmology, New Zealand National Eye Centre, University of Auckland, New Zealand. Authors: Y Chen, C R Green, R Teague, J Perrett, H V Danesh-Meyer, I Toth, I D Rupenthal. VIEW ABSTRACT

Nanoparticles in Tumor Treatment     [RETURN TO TOP]

52  Invited Speaker: Nanocarrier’s Function Integration and Synchronization for Cancer Drug Delivery Cascade. Presenter: Youqing Shen , Zhejiang Univ, China. Authors: Y Shen, X Sun. VIEW ABSTRACT

53  Nanoparticles Targeting Pancreatic Tumor. Presenter: Simona Mura , Faculty of Pharmacy Institut Galien Paris-Sud UMR CNRS 8612, France. Authors: S Mura, S Valetti, F Maione, B Stella, D Desmaële, M Noiray, J Vergnaud, C Vauthier, L Cattel, E Giraudo, P Couvreur. VIEW ABSTRACT

54  Folate-conjugated PEG-derivatized Embelin as A Versatile Nanocarrier for the Targeted Delivery of Doxorubicin with Reversal of Multidrug Resistance. Presenter: Jianqin Lu , University of Pittsburgh, U.S.A.. Authors: J Lu, Y Huang, W Zhao, H Liu, R B Gibbs, J Li, S Li. VIEW ABSTRACT

56  Anticancer polymeric nanomedicine bearing synergistic drug combination. Presenter: Ela Markovsky , Tel Aviv University, Israel. Authors: E Markovsky, H Baabur-Cohen, R Satchi-Fainaro. VIEW ABSTRACT

612  Targeted Cellular Interactions of Dendron Micelles using PEG linkers  . Presenter: Ryan Pearson , University of Illinois at Chicago, U.S.A.. Authors: R M Pearson, M Pasko, M Gaske, H Hsu, P Kral, S Hong. VIEW ABSTRACT

Overcoming Barriers in the GI Tract     [RETURN TO TOP]

57  Invited Speaker: Overcoming gastrointestinal barriers to nanoparticle delivery. Presenter: Laura Ensign , Johns Hopkins Hospital, U.S.A.. Authors: K Maisel, M Reddy, R Cone, J Hanes, L Ensign. VIEW ABSTRACT

58  A biomimetic strategy for gastric targeting based on Helicobacter pylori  . Presenter: Naim Hage , University of Nottingham, United Kingdom. Authors: N A Hage, S Winkler, P Gellert, S Stolnik, F H Falcone. VIEW ABSTRACT

59  Nanostructured lipid-based mucoadhesive particles formed from pH responsive vesicles. Presenter: Ben Boyd , Monash Institute of Pharmaceuitcal Sciences, Australia. Authors: J Du, T Nguyen, Q Liu, B J Boyd. VIEW ABSTRACT

60  Intestinal mucosa permeability following oral delivery of wheat germ agglutinin non-sheddable nanocage stabilized nanocrystals. Presenter: Dengning Xia , Shanghai Institute of Materia Medica, Chinese Academy of Sciences, China. Authors: D Xia, J Tao, Y He, F Cui, Y Gan. VIEW ABSTRACT

61  Magnetic Beads to Enhance Drug Penetration Across Intestinal Membrane. Presenter: Anjali Seth , University Pierre et Marie Curie, France. Authors: A Seth, D Lafargue, C Poirier, J Péan. VIEW ABSTRACT

Predictive Animal Models for Assessing Long-Acting Formulations for Human and Animal Health and Their Challenges     [RETURN TO TOP]

62  Invited Speaker: Models for Predicting Functional Response to Drug and Vaccine Delivery To and Through Skin . Presenter: James Birchall , Cardiff University, Wales. Authors: J C Birchall. VIEW ABSTRACT

63  Composite Coatings to Suppress the Foreign Body Response in a Large Animal Model. Presenter: Michail Kastellorizios , University of Connecticut, Department of Pharmaceutical Sciences, U.S.A.. Authors: M Kastellorizios, F Papadimitrakopoulos, D J Burgess. VIEW ABSTRACT

64  Multimodal Imaging-Based Characterization of HER2+ and Triple Negative Metastatic Breast Cancer Xenograft Models in Mice. Presenter: Raquel De Souza , Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, M5G 1L7, Canada, Canada. Authors: R De Souza, J Zheng, S Serra, G Francia, R Kerbel, C Allen, D Jaffray. VIEW ABSTRACT

65  A Canine Biorelevant Dissolution Method for Predicting in vivo Performance of Sustained Release Solid Oral Dosage Forms. Presenter: Paul Walsh , Merck & Co., U.S.A.. Authors: P L Walsh, S Bhardwaj, M Hu, R Nofsinger, J Mann, A Djemai. VIEW ABSTRACT

66  Critical attributes for a generic nanosuspension development: physical properties along with in vitro release.. Presenter: Ruby K , Centre of Excellence- Bio Studies, India. Authors: R P K, P K Kondamudi, B S Yeola, H P Bhagwatwar, D Aggarwal. VIEW ABSTRACT

Mini Symposia: Micro- and Nano-Encapsulation: From Innovation to Commercialization     [RETURN TO TOP]

67  Invited Speaker: Progress in Complex Parenteral Formulations for the Delivery of BIopharmaceuticals and Samll Molecules - Microencapsulation Scale Up and Product Enhancements. Presenter: Tom Tice , Evonik, U.S.A.. Authors: T Tice. VIEW ABSTRACT

68  Invited Speaker: Taste-masked Powders for Pediatric-centric Dispersed Dosage Formats. Presenter: Nathan Dormer , Orbis Biosciences, Inc., U.S.A.. Authors: N Dormer, D W Dumbauld, T Zhang, C Berkland. VIEW ABSTRACT

69  Invited Speaker: The Determination of Cost and the Economics for Controlled Release Processes. Presenter: Ronald Veršic , Ronald T Dodge Co, U.S.A.. Authors: R J Veršic. VIEW ABSTRACT

Advances in Drug Delivery to the Lung     [RETURN TO TOP]

70  Invited Speaker: Advances in Drug Delivery to the Lung: A Controlled Release Perspective. Presenter: Paul Young , The Woolcock Institute of Medical Research, Australia. Authors: P M Young, D Traini. VIEW ABSTRACT

71  Highly Sensitive and Selective Anti-cancer Effect by Conjugated HA-Cisplatin in CD44 Overexpression Non-small Cell Lung Cancer. Presenter: Hyun Koo Kim , Department of Thoracic and Cardiovascular Surgery, Korea University Guro Hospital, Korea University College of Medicine, Korea. Authors: Y Quan, H Kim, B Kim, J Park, Y Choi, Y Choi. VIEW ABSTRACT

72  Pulmonary co-delivery system for lung tumor treatment. Presenter: Huayu Tian , Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, China. Authors: H Tian, C Xu, P Wang, X Chen. VIEW ABSTRACT

73  Lung toxicity of biodegradable nanoparticles evaluated in vitro on co-cultures and in vivo in mice. Presenter: Elias Fattal , University of Paris Sud, France. Authors: E Fattal, N Grabowski, L Santiago Aragao, H Hillaireau. VIEW ABSTRACT

74  A New Strategy to Enhance Antibiotic Load for Pulmonary Treatment of Cystic Fibrosis Infections: Ciprofloxacin Lipid Complex Loaded PLGA Nanoparticles. Presenter: Nazende Günday Türeli , MJR PharmJet GmbH & Philipps University Marburg, Germany. Authors: N Günday Türeli, J Juntke, A Torge, E A Türeli, E Prinz, C de Souza Carvalho, N Daum, C Lehr, M Schneider. VIEW ABSTRACT

Controlled Release Applications in Food, Feed, and Beverages     [RETURN TO TOP]

75  Invited Speaker: Tailoring gastric food structure disintegration and function release kinetics by gastrointestinal structure engineering (GINSENG). Presenter: Erich Windhab , ETH-Zurich, Switzerland. Authors: E J Windhab. VIEW ABSTRACT

76  Elaboration and Characterization of Barley Protein Nanoparticles as an Oral Delivery System for Lipophilic Bioactive Compounds. Presenter: Jingqi Yang , University of Alberta, Canada. Authors: J Yang, Y Zhou, L Chen. VIEW ABSTRACT

77  Doubled-layered emulsions as delivery systems to reduce the degradation of Coenzyme Q10 and control its release at the absorption site. Presenter: Qixin Zhong , University of Tennessee, U.S.A.. Authors: Y Guan, Q Zhong. VIEW ABSTRACT

78  Effect of Physical Properties of Enzymatically-Modified Starch Gels on Salt Release of the Gel-Containing Water-in-Oil-in-Water Emulsions. Presenter: YOUNGLIM KIM , Y.L. KIM, Korea. Authors: Y KIM, S MUN, S RHO, Y KIM. VIEW ABSTRACT

79  In vitro and in vivo release of carvacrol encapsulated in Ca-alginate microspheres. Presenter: Qi Wang , Agriculture and Agri-Food Canada, Canada. Authors: Q Guo, Y Yang, Y Zhang, H Yu, J Gong, Q Wang. VIEW ABSTRACT

Innovations in Micro- and Nano-Based Delivery     [RETURN TO TOP]

80  Invited Speaker: Oxidation- and pH-Activated MRI agents based on Triggered Degradation of Polymeric Nanoparticles. Presenter: Adah Almutairi , Univ of California, U.S.A.. Authors: M L Viger, J Sankaranarayanan, C de Gracia Lux, M Chan, J Lux, A Almutairi. VIEW ABSTRACT

81  Programmable Release of a Water-Soluble Drug from Electrospun Nanofibers for HIV Inhibition. Presenter: Daniel Carson , University of Washington, U.S.A.. Authors: D S Carson, K A Woodrow. VIEW ABSTRACT

82  Recognizable polyacrylamide in microbubbles for in situ detection of colon malignancy    . Presenter: Abraham Rubinstein , The Hebrew University of Jerusalem, School of Pharmacy, Israel. Authors: A Rubinstein, M Bloch, E Yavin, L Jablonowski, M Wheatley, A Nyska. VIEW ABSTRACT

83  PLGA-LL37 NP promote wound healing. Presenter: Kiran Kumar Chereddy , Université catholique de Louvain, Louvain Drug Research Institute, Pharmaceutics and Drug Delivery, Belgium. Authors: K Chereddy, C Her, C Moia, J Vanacker, A des Rieux, H Zhu, G Vandermeulen, V Préat. VIEW ABSTRACT

84   Inactivated Polio Vaccination Using a Microneedle Patch. Presenter: Jessica Joyce , Georgia Institute of Technology, U.S.A.. Authors: J Joyce, C Edens, H Eichenbaum, N Dybdahl-Sissoko, J Norman, W Weldon, S Oberste, M Prausnitz. VIEW ABSTRACT

Proteins, Peptides, and Vaccines     [RETURN TO TOP]

85  Invited Speaker: NANOBIOPHARMACEUTICALS: THE DELIVERY KEY FOR PEPTIDES, PROTEINS AND VACCINES. Presenter: Maria Alonso , Univ of Santiago de Compostela, Spain. Authors: M J Alonso. VIEW ABSTRACT

86  Bone-Targeting Parathyroid Hormone Analogues Outperform Unmodified PTH in the Anabolic Treatment of Osteoporosis in Rats. Presenter: Yang Yang , Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Canada. Authors: Y Yang, A Panahifar, Y Wu, K Tang, K H Bhandari, M R Doschak. VIEW ABSTRACT

87  Dual labeled polymeric nanoparticles loaded with ovalbumin as model cancer vaccine formulation: In vivo tracking and evaluation of T cell response. Presenter: Sima Rahimian , Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Netherlands. Authors: S Rahimian, J Kleinovink, M F Fransen, M Amidi, L Mezzanotte, W E Hennink, F Ossendorp. VIEW ABSTRACT

88  RNAdjuvant®, a novel RNA-based immunomodulator, combines strong immunostimulatory capacities with a favourable safety profile. Presenter: Patrick Baumhof , CureVac GmbH, Germany. Authors: P Baumhof, R Heidenreich, B Scheel, S Voss, K Kallen, M Fotin-Mleczek. VIEW ABSTRACT

89  Enhanced DNA vaccination using microsphere/polyplex-releasing multi-layered microneedles. Presenter: Nak Won Kim , Sungkyunkwan University, South Korea. Authors: N Kim, M Lee, J Lee, Y Cho, j Jeong. VIEW ABSTRACT

Mini Symposia: Cancer Epigenetics, Epigenetic Drugs and Delivery     [RETURN TO TOP]

90  Invited Speaker; Spatiotemporal delivery of epigenetic and chemotherapeutic nucleoside analogs to pancreatic cancer. Presenter: Rajgopal Govindarajan , University of Georgia, U.S.A.. Authors: R Govindarajan. VIEW ABSTRACT

91  Invited Speaker: Epigenetic Nanotherapy. Presenter: Vinod Labhasetwar , Cleveland Clinic Foundation, U.S.A.. Authors: V Labhasetwar. VIEW ABSTRACT

92  Invited Speaker: Targeting DNA hypermethylation by nanomedicine for acute myeloid leukemia therapy. Presenter: Shujun Liu , Univ of Minnesota, U.S.A.. Authors: S Liu, F Yan, N Shen, J Pang. VIEW ABSTRACT

Breakthrough Technologies     [RETURN TO TOP]

93  Invited Speaker: Edible Electronics: Next generation medical devices for oral delivery. Presenter: Chris Bettinger , Carnegie-Mellon USA, U.S.A.. Authors: C J Bettinger. VIEW ABSTRACT

94  From Laboratory to Pilot Scale: Advanced Dosage Forms of Protein/Peptide Medicines. Presenter: Tuo Jin , Shanghai Jiao Tong University, China. Authors: T Jin, Z Hu, S Yang, X Hong, W Yuan, F Wu, H Zhu, Z Yin. VIEW ABSTRACT

95  Platform-Technology Based on Prodrug/Enzyme Systems for Rapid Absorption of Hydrophobic Drugs: Toward Intranasal Treatment of Seizure Emergencies. Presenter: Mamta Kapoor , University of Minnesota, U.S.A.. Authors: M Kapoor, R A Siegel. VIEW ABSTRACT

96  High Surface Area Porous Polypyrrole Structures for Glutamate Delivery. Presenter: Darren Svirskis , University of Auckland, New Zealand. Authors: D M Svirskis. VIEW ABSTRACT

97  Rational design of wet spun monofilaments and multifilament yarns as controlled-release drug delivery systems for biomedical applications. Presenter: Danya Lavin , Brown University, U.S.A.. Authors: D M Lavin, L Zhang, R A Hopkins, E Mathiowitz. VIEW ABSTRACT

Cells as Delivery Vehicles     [RETURN TO TOP]

98  Invited Speaker: Cells as Delivery Vehicles. Presenter: Maciej Lesniak , Univ of Chicago, U.S.A.. Authors: M S Lesniak. VIEW ABSTRACT

99  Development of nanotechnology based imaging technique for tracking stem cells within the brain: Cell therapy application for depression disorders. Presenter: Oshra Betzer , Gonda Brain Research Center, Bar Ilan University, Israel. Authors: O Betzer, A Shwartz, G Yadid, C Brodie, R Popovtzer. VIEW ABSTRACT

100  Potential use of engineered B. choshinensis in in situ TNF-a production machine in the tumor of xenograft mice and its antitumor effects. Presenter: Hidefumi Mukai , RIKEN Center for Life Science Technologies, Japan. Authors: H Mukai, M Takahashi, Y Watanabe. VIEW ABSTRACT

239  Local delivery of stem cells on BMP-7 nanoparticle-loaded fibrous scaffold for enhanced articular cartilage repair. Presenter: Heejung Kim , Ewha womans university, Korea. Authors: H Kim, S Do, S Lee. VIEW ABSTRACT

385  Multifunctional delivery systems for encapsulated islet cell therapy. Presenter: Danya Lavin , MIT, U.S.A.. Authors: D M Lavin, S Jhunjhunwala, S Aresta-DaSilva, R Langer, D G Anderson. VIEW ABSTRACT

Controlled Release of Actives in Consumer Products     [RETURN TO TOP]

103  Invited Speaker: Physico-chemical Challenges of Designing Delivery Systems for Consumer and Industrial Applications. Presenter: Nilesh Shah , The Dow Chemical Company, U.S.A.. Authors: N Shah. VIEW ABSTRACT

104  Development and Evaluation of Resveratrol and Vitamin E Acetate-loaded Solid Lipid Nanoparticles for Skin Care Applications. Presenter: Jin Chen , Kimberly-Clark Corporation, U.S.A.. Authors: J Chen, N Wei, M Lopez-Garcia, C Annelin, D Ambrose, D Devine, T Peterson. VIEW ABSTRACT

718  Biocompatible Dendritic Nanogels for Thermally Triggered Skin Penetration. Presenter: Mazdak Asadian-Birjand , Freie Universität Berlin, Germany. Authors: M Asadian-Birjand, F Rancan, J C Cuggino, K Achazi, R C Mutihac, J Dernedde, A Vogt, M Calderón. VIEW ABSTRACT

723  Efficient Ibuprofen Delivery by a Novel Semi-Solid Silicone Formulation: In-vitro and In-vivo Study. Presenter: Hyder Aliyar , Dow Corning Corporation, U.S.A.. Authors: H A Aliyar, R O Huber, G L Loubert, G K Schalau II. VIEW ABSTRACT

107  Influence of the vehicle type on the in-vitro skin permeation of acetyl hexapeptide-8. Presenter: Magdalena Hoppel , University of Vienna, Austria. Authors: M Hoppel, D Mahrhauser, G Reznicek, C Valenta. VIEW ABSTRACT

Novel Development in Formulation, Analytical Chemistry, and Processing in Animal Health and Preclinical Sciences     [RETURN TO TOP]

108  Invited Speaker: Advances in Veterinary Extended Release Injectables Formed in situ and a Case Study. Presenter: Susan Cady , Merial Ltd, U.S.A.. Authors: S M Cady. VIEW ABSTRACT

109  Biodistribution of nanosized liposomes loaded with immunostimulants in zebrafish and rainbow trout, and vaccination efficacy in zebrafish. Presenter: Angels Ruyra , IBB/ICN2, Universitat Autònoma de Barcelona, Spain. Authors: A Ruyra, M Cano-Sarabia, P Garcia-Valtanen, D Yero, I Gibert, S Mackenzie, A Estepa, N Roher, D Maspoch. VIEW ABSTRACT

111  Examination of Polymer Swelling and API Release of Controlled Release Formulations at the Solid-Liquid Interface by UV Surface Imaging. Presenter: Christopher Zordan , Bristol-Myers Squibb, U.S.A.. Authors: C A Zordan, X Lu. VIEW ABSTRACT

112  Nano-Emulsions for Biomedical Imaging. Presenter: Thierry Vandamme , University of Strasbourg, France. Authors: N Anton, M Attia, X Li, T Vandamme. VIEW ABSTRACT

635  Investigation into the Topical Delivery of Diclofenac into Equine Skin. Presenter: Sergio del Río-Sancho , University of Geneva / School of Pharmaceutical Sciences, Switzerland. Authors: S del Río-Sancho, D Concas, P Oreste, G Zoppetti, P H Briggs, Y N Kalia. VIEW ABSTRACT

Mini Symposia: Individualized Medicine and Theranostics     [RETURN TO TOP]

113  Invited Speaker: Nanomedicines and Theranostics: Image-guided and Targeted Treatments for Individualized and Improved Interventions. Presenter: Twan Lammers , RWTH Aachen, Germany. Authors: T Lammers. VIEW ABSTRACT

114  Invited Speaker: Nanomedical Technology in Personalized Cancer Medicine. Presenter: Yong-Min Huh , Yonsei University, Korea. Authors: Y Huh. VIEW ABSTRACT

115  Invited Speaker: A Versatile Nanoplatform for Systemic Delivery of RNAis. Presenter: Xiaoyuan Chen , NIH, U.S.A.. Authors: K Choi, O F Silvestre, X Chen. VIEW ABSTRACT


POSTER PRESENTATIONS

Advances in Drug Delivery to the Eye     [RETURN TO TOP]

116  Biomechanical effect of low-intensity and low-frequency ultrasound on cellular transport of retinal pigment epithelium cells. Presenter: W L Suen, The Hong Kong University of Science and Technology, Hong kong. Authors: W L Suen, Y Chau. VIEW ABSTRACT

117  Bovine Serum Albumin-Meloxicam Nanoaggregates Laden Contact Lenses for Ophthalmic Drug Delivery in Treatment of Postcataract Endophthalmitis. Presenter: W Zhang, Shenyang Pharmaceutical University, China. Authors: W Zhang, Q Zhang, S Li, W Pan. VIEW ABSTRACT

118  Development of Gatifloxacin loaded Eudragit nanoparticles for ocular drug delivery. Presenter: R Al-Kassas, University of Auckland, New Zealand. Authors: R Al-Kassas. VIEW ABSTRACT

119  Eudragit coated  Genistein-loaded NLC for pre-corneal drug delivery. Presenter: W Pan, Shenyang Pharmaceutical University, China. Authors: W Pan, W Zhang, S Li, J Kong. VIEW ABSTRACT

120  Extended Release of DMPC from Silicone Hydrogel Contact Lenses. Presenter: W G Pitt, Brigham Young University, U.S.A.. Authors: W G Pitt, Y Zhao, K X Perez, D R Jack, J L Nelson, J D Pruitt. VIEW ABSTRACT

121  Extended Release of Ovalbumin as a Model for Ranibizumab in an Ocular Drug Delivery System. Presenter: C R Osswald, Illinois Institute of Technology, U.S.A.. Authors: C R Osswald, J J Kang-Mieler. VIEW ABSTRACT

122  Folate-decorated nanoparticles exhibit size-dependent internalization and prolonged anti-angiogenic activity in retinal pigment epithelium cells . Presenter: W L Suen, The Hong Kong University of Science and Technology, Hong kong. Authors: W L Suen, Y Chau. VIEW ABSTRACT

123  Formulation and Development of Cyclosporine loaded Lectin Anchored Chitosan Nanoparticles for Ocular Drug Delivery. Presenter: K K Singh, School of Pharmacy and Biomedical Sciences, University of Cental Lancashire, Preston, United Kingdom. Authors: K K Singh, S B Kamble. VIEW ABSTRACT

124  In situ-gelling hydrogels for ophthalmic drug delivery using a microinjection device. Presenter: S Campbell, McMaster University, Canada. Authors: S Campbell, J Yang, P Selvaganapathy, T Hoare. VIEW ABSTRACT

125  In vitro Transscleral Iontophoresis of Moxifloxacin Hydrochloride. Presenter: S Gungor, Istanbul University, Turkey. Authors: B Mesut, Y Ozsoy, S Gungor. VIEW ABSTRACT

126  Lipid and polymeric nanoparticles designed for the treatment of corneal vascularization. Presenter: E M Lima, UFG, Brazil. Authors: L G Souza, E M Lima. VIEW ABSTRACT

127  Modulation of scleral structure by low intensity and low frequency ultrasound. Presenter: W L Suen, The Hong Kong University of Science and Technology, Hong kong. Authors: W L Suen, J Jiang, H Wong, J Qu, Y Chau. VIEW ABSTRACT

128  Nanotheranostic liposomes for ocular delivery. Presenter: H F Salem, Faculty of Pharmacy,, Beni suef University, Egypt. Authors: H F Salem, M M Omar, S M Mohammed. VIEW ABSTRACT

129  Ocular tolerability of chitosan nanoparticles loaded with the antioxidant prodrug 2-oxothiazolidine-4-carboxylic acid. Presenter: A A Al-kinani, School of Pharmacy and Chemistry, Kingston University London, United Kingdom. Authors: A A Al-kinani, R Kirk, A Vangala, G Calabrese, B K Pierscionek, D P Naughton, R G Alany. VIEW ABSTRACT

130  Particle-Stabilized Emulsion Droplets for Gravity-Mediated Targeting in the Posterior Segment of the Eye. Presenter: Y C Kim, Georgia Institute of Technology, U.S.A.. Authors: Y C Kim, H Edelhauser, M Prausnitz. VIEW ABSTRACT

133  Sulprostone-loaded Polylactic Acid Microspheres for Treatment of Glaucoma. Presenter: K Nieto, University of Michigan, U.S.A.. Authors: K Nieto. VIEW ABSTRACT

136  SynBiosys microspheres as a platform for local delivery of Sunitinib: Formulation and characterization. Presenter: F Ramazani, Utrecht University, Netherlands. Authors: F Ramazani, C Hiemstra, R Steendam, M J Van Steenbergen, R C Van Nostrum, G Storm, W E Hennink, R J Kok. VIEW ABSTRACT

137  Synthesis and Properties of Novel Hydrogel Containing Organic Nanotubes as a Contact Lens. Presenter: Y Yamazaki, SEED CO., LTD., Japan. Authors: Y Yamazaki, T Sato, W Ding, M Masuda. VIEW ABSTRACT

Advances in Drug Delivery to the Lung     [RETURN TO TOP]

138  A nicotinic acetylcholine receptor a1-specific aptide for potential use in pulmonary drug delivery. Presenter: S Park, GIST, South Korea. Authors: S Park, S Jon. VIEW ABSTRACT

140  Ceramic Nano-assembly for Pulmonary Delivery of Protein and Peptides. Presenter: D Lowry, Aston University, United Kingdom. Authors: F A Abdulrazzaq, D Lowry, Y Perrie, L J Marshall. VIEW ABSTRACT

141  Curcumin nanoparticles attenuates inflammation caused by macrophages: effects of nanoparticles’ surface charges. Presenter: W Lee, Respiratory Technology, Woolcock Institute of Medical Research, University of Sydney, NSW 2037, Sydney, Australia, Australia. Authors: W Lee, C Loo, P M Young, R Rohanizadeh, D Traini. VIEW ABSTRACT

143  In Vivo Delivery, Pharmacokinetic Analysis and  Stability Study Of A DPI Formulation of Nanocrystalline Camptothecin for the Treatment of Lung Cancer. Presenter: D B DuBose, Bend Research Inc, U.S.A.. Authors: D B DuBose, J F Breit, D Vodak. VIEW ABSTRACT

144  Local Lung Co-Delivery of siRNA and Drug. Presenter: V Ivanova, Department of Pharmaceutics, Rutgers, the State University of New Jersey, U.S.A.. Authors: V Ivanova, O B Garbuzenko, R Rustamov, G Mainelis, T Minko. VIEW ABSTRACT

145  NanoXCT: A New Technique to Probe the Interior of Pharmaceutical Particles for Inhalation. Presenter: J Wong, University of Sydney, Australia. Authors: J Wong, D D'Sa, M Foley, J Chan, H Chan. VIEW ABSTRACT

146  Non-cytotoxic silver nanoparticles-polyvinyl alcohol hydrogels with anti-biofilm activity as coatings for endotracheal tube materials. Presenter: C Loo, Respiratory Technology, Woolcock Institute of Medical Research, University of Sydney, NSW 2037, Sydney, Australia, Australia. Authors: C Loo, P M Young, W Lee, R Cavaliere, D Traini, C B Whitchurch, R Rohanizadeh. VIEW ABSTRACT

147  Novel PEG-PLA/PLGA microparticles having porous surfaces for pulmonary drug delivery. Presenter: T Takami, Tokyo University of Agriculture and Technology, Japan. Authors: T Takami, Y Murakami. VIEW ABSTRACT

Advances in Process Engineering - New Methods for the Production of Particles, Capsules, and Coatings     [RETURN TO TOP]

151  Application of Hydroxypropyl Cellulose to Solubility Enhancement of Poorly Soluble Drugs. Presenter: K Sugisawa, Nippon Soda Co., Ltd., Japan. Authors: K Sugisawa, S Tsue, A Sarode, D Worthen. VIEW ABSTRACT

152  Breakthrough and Advances in High-Throughput Core-Sheath Electrospinning Technology. Presenter: T Freyman, Arsenal Medical, U.S.A.. Authors: X Yan, Q Pham, R Mulligan, J Marini, T Freyman. VIEW ABSTRACT

156  Evaluation of Hydroxypropyl Cellulose for Orally Disintegrating Film Drug Application. Presenter: K Sugisawa, Nippon Soda Co., Ltd., Japan. Authors: K Sugisawa, S Tsue, Y Takeuchi, H Takeuchi. VIEW ABSTRACT

158  Grafting a pH-sensitive Stealth Layer on Polymeric Nanoparticles using the Bioinspired Dopamine Polymerization Method. Presenter: S Ahmed, Purdue University, U.S.A.. Authors: S Ahmed, Y Ku, Y Yeo. VIEW ABSTRACT

159  Homogeneous and Reproducible Preparation of Chitosan/Nucleic Acid (NA) Nanoparticles Using an Automated Inline Mixing System. Presenter: A Tavakoli Naeini, Ecole Polytechnique de Montreal, Canada. Authors: A Tavakoli Naeini, M Lavertu, K Biniecki, M Buschmann. VIEW ABSTRACT

160  In Situ Forming Growth Factor-loaded Microparticle-embedded Hydrogels for Directing Stem Cell Fate. Presenter: O Jeon, Case Western Reserve University, U.S.A.. Authors: O Jeon, D Wolfson, E Alsberg. VIEW ABSTRACT

161  Microfluidic Templated Multistage Porous Silicon Based Platform for Enhanced Enteric Cancer Drug Delivery . Presenter: H Zhang, University of Helsinki, Finland. Authors: H Zhang, D Liu, Shahbazi, E Mäkilä, J Salonen, J Hirvonen, H Santos. VIEW ABSTRACT

165  Statistical Modeling – A Tool for Interpreting the Correlation between Critical Process Parameters and Responses for Wurster Processing. Presenter: D K Sahoo, 1, India. Authors: D K Sahoo, S K BV, R R Gandhi, K K Venkatesh, N Vaya, P K Ghosh. VIEW ABSTRACT

166  Thermo-responsive Nanogel Synthesis by Strain Promoted Azide Alkyne Cycloaddition. Presenter: M Giulbudagian, Freie Universität Berlin, Germany. Authors: M Giulbudagian, M Asadian-Birjand, D Steinhilber, K Achazi, M Molina, M Calderón. VIEW ABSTRACT

745  Liposomes for triggered drug delivery: effect of lipid composition on the sensitivity of liposomes to 1.1 MHz ultrasound. Presenter: H Mujoo, University of Otago, New Zealand. Authors: H Mujoo, J Reynolds, I G Tucker. VIEW ABSTRACT

Advances in RNA and DNA Delivery     [RETURN TO TOP]

167  A nano-liposomal formulation of DOTAP/DOPE/cholesterol for transfecting murine osteosarcoma cells in vitro. Presenter: j J ambrose, Louisiana tech university, U.S.A.. Authors: j J ambrose, P khoshkenar, d K mills, m rasoolian, l tayebi. VIEW ABSTRACT

170  Biodegradable intravaginal film for the targeted delivery of siRNA-loaded nanoparticles to immune cells. Presenter: J Gu, University of Manitoba, Canada. Authors: J Gu, S Yang, E Ho. VIEW ABSTRACT

171  Biodegradable starch derivatives for gene delivery. Presenter: H Yamada, Department of Drug Delivery (DDEL), Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz-Center for Infection Research (HZI), Germany. Authors: H Yamada, B Loretz, C Lehr. VIEW ABSTRACT

172  Bio-responsibility and stability balance for designing polycationic carriers of nucleic acids. Presenter: S Chen, School of Pharmacy, Shanghai Jiao Tong University, China. Authors: S Chen, W Yuan, T Jin. VIEW ABSTRACT

173  Brain Penetrating Nanoparticles for Brain Gene Therapy. Presenter: P Mastorakos, Department of Ophthalmology, Johns Hopkins University School of Medicine, U.S.A.. Authors: P Mastorakos, S Berry, C Zhang, A Kim, G Woodworth, J Suk, J Hanes. VIEW ABSTRACT

174  Cationic phosphorous dendrimers as complexing agents for siRNA delivery. Presenter: A Bohr, University of Paris-Sud, France. Authors: A Bohr, N Tsapis, J Majoral, C Foged, E Fattal. VIEW ABSTRACT

175  Chitosan/siRNA nanoparticles demonstrate in vitro superior silencing efficiency with minimal toxicity compared to lipid standard.. Presenter: M Alameh, Ecole Polytechnique de Montreal, Canada. Authors: M Alameh. VIEW ABSTRACT

176  CTGF siRNA-Nanomedicine; A Potential Treatment for Renal Fibrosis. Presenter: F Khaja, university of Illinois at Chicago, U.S.A.. Authors: F Khaja, H Onyuksel. VIEW ABSTRACT

177  Delivery of GLP-1 gene and DPP-4 siRNA using chitosan-based nanoparticles for Type-2 Diabetes treatment. Presenter: M Jean, Ecole Polytechnique de Montreal, Canada. Authors: M Jean, D Jeandupeux, A Merzouki, M D Buschmann. VIEW ABSTRACT

178  Development of Modified Pectic Galactan Nano-System for Targeted Gene Therapy. Presenter: N Buaron, Ben-Gurion University of the Negev, Israel. Authors: N Buaron, R Goldbart, T Traitel, H Brem, J Kost. VIEW ABSTRACT

179  Dual drug-loaded solid lipid nanoparticles for enhanced cancer stem cell therapy. Presenter: X Sun, Sichuan University, China. Authors: X Sun, S Shi, T Gong, Z Zhang. VIEW ABSTRACT

180  Efficient Delivery of siRNA by Hyaluronic Acid-modified Lipoplexes Targeting CD44 Receptors. Presenter: T L Nascimento, Institut Galien Paris-Sud, Université Paris-Sud 11, France. Authors: T L Nascimento, H Hillaireau, D Courilleau, M Noiray, G Pehau-Arnaudet, M Taverna, S Arpicco, E Fattal. VIEW ABSTRACT

181  Enhanced transfection of human stem cells using hyaluronic acid/calcium phosphate hybrid gene delivery system. Presenter: J Lee, Sungkyunkwan University, South Korea. Authors: J Lee, M Lee, Y Cho, C Cho, J Jeong. VIEW ABSTRACT

182  Experimental and Computational Approaches to Probe the Mechanism of Shape Control in PEG-Polycation/DNA Micelle Assembly. Presenter: J Williford, Johns Hopkins University, U.S.A.. Authors: J Williford, Y Ren, W Qu, M Archang, K Huang, Z Wei, E Luijten, H Mao. VIEW ABSTRACT

183  Exploring Redox Responsive Polymeric Drug Delivery System for Codelivery of Hydrophobic Drug and Silencing RNAs. Presenter: Y Zhang, Department of Biopharmaceutical Sciences, University of Illinois, Chicago, U.S.A.. Authors: Y Zhang, Y Liu, J Buhrman, R A Gemeinhart. VIEW ABSTRACT

185  Human Relaxin Gene Therapy using Dendrimer Bioreducible Polymer of Myocardial Infarction in Rats. Presenter: Y Lee, University of Utah, U.S.A.. Authors: Y Lee, J Kim, K Nam, I Choi, C Yun, S Kim. VIEW ABSTRACT

186  Intravaginal Gel for the Targeted Delivery of siRNA to T-cells as a Potential Strategy for HIV-1 Prevention. Presenter: S Yang, Laboratory for Drug Delivery and Biomaterials, Faculty of Pharmacy, University of Manitoba, Canada. Authors: S Yang, J Gu, E A Ho. VIEW ABSTRACT

187  Knockdown of Apolipoprotein B by Chitosan/ApoB-siRNA Nanoparticles Lowers Plasma Cholesterol in Atherosclerosis Mouse Model. Presenter: M Jean, Ecole Polytechnique de Montreal, Canada. Authors: M Jean, R Derbali, D De Jesus, D Jeandupeux, A Merzouki, M D Buschmann. VIEW ABSTRACT

188  Knockdown of P-glycoprotein by Chitosan/MDR1-siRNA Nanoparticles Increases Sensitivity to Chemotherapeutics. Presenter: M Jean, Ecole Polytechnique de Montreal, Canada. Authors: M Jean, M Benhammadi, A Siddiqui, D Jeandupeux, A Merzouki, M D Buschmann. VIEW ABSTRACT

189  Light-responsive Complex for shRNA Delivery in Cancer Therapy. Presenter: K Na, The Catholic University of Korea, Korea. Authors: W Park, K Na. VIEW ABSTRACT

190  Lyophilisation and concentration of chitosan polyelectrolyte complexes for delivery of DNA and siRNA. Presenter: D Veilleux, Ecole Polytechnique de Montreal, Canada. Authors: D Veilleux, A Tavakoli Naeini, M Lavertu, K Biniecki, M D Buschmann. VIEW ABSTRACT

191  Micelle-like nanoparticles as “two-in-one” platform for targeted delivery of siRNA/drug combinations in cancer therapy. Presenter: G Navarro, Northeastern University, U.S.A.. Authors: G Navarro, R R Sawant, S Biswas, S Essex. VIEW ABSTRACT

193  Nanocarrier for Sustained siRNA Delivery. Presenter: X Zhu, Brigham and Women's Hospital, Harvard Medical School, U.S.A.. Authors: X Zhu, J Shi, O Farokhzad. VIEW ABSTRACT

194  Nanohydroxyapatite-based microRNA delivery on Collagen-nanohydroxyapatite Scaffolds for Bone Tissue Engineering. Presenter: I Mencia Castaño, Tissue Engineering Research Group, Dept. of Anatomy, Royal College of Surgeons in Ireland, Dublin, Ireland. Authors: I Mencia Castaño, C M Curtin, G P Duffy, F J O'Brien. VIEW ABSTRACT

195  Nanoparticle delivery of siRNA targeting the oncogenic histone modifying enzyme GASC1 in breast cancer. Presenter: S Movassaghian, Department of Pharmaceutical Sciences, Eugene Applebaum Colley of Pharmacy and Health Sciences, Wayne State University, Detroit, MI, U.S.A.. Authors: C Hildebrandt, R Rosti, S Movassaghian, O Merkel. VIEW ABSTRACT

196  Novel nanostructured lipid carriers dedicated to nucleic acid delivery for RNAi purposes. Presenter: F P Navarro, CEA, LETI-MINATEC, Département des Technologies pour la Biologie et la Santé, 17 rue des Martyrs, F-38054 Grenoble, France, France. Authors: J Bruniaux, E Sulpice, F Mittler, M Menneteau, T Bastogne, I Texier, X Gidrol, F P Navarro. VIEW ABSTRACT

198  Oligopeptide-Modified Glycol chitosan for Gene Delivery. Presenter: E Jeong, Hanyang University, South Korea. Authors: E Jeong, K Lee. VIEW ABSTRACT

199  Overcoming transport barriers using modified starch based nanoparticles and ultrasound application for gene silencing . Presenter: E Amar-Lewis, Ben-Gurion University of the Negev, Beer-Shava, Israel. Authors: E Amar-Lewis, R Goldbart, T Traitel, D Landesman-Milo, D Peer, J Kost. VIEW ABSTRACT

201  Phospholipid-modified PEI-based nanocarriers for in vivo siRNA therapeutics against multi-drug resistant tumors. Presenter: G Navarro, Northeastern University, U.S.A.. Authors: S Essex, G Navarro, P Sabhachandani, A Ciordia, M Trivedi, V Torchilin. VIEW ABSTRACT

202  Polyamines and nucleic acid interaction: a structure property relationship study. Presenter: V Kolhatkar, University of Illinois at Chicago, U.S.A.. Authors: V Kolhatkar, A Lote. VIEW ABSTRACT

203  Preparation of intranasal chitosan/siRNA nanoparticles for inhibition of Influenza A virus in infected cells. Presenter: F Dorkoosh, Tehran Univ, Iran. Authors: M Dinarvand, A Esmailie, A Jamali, M Tavassoti Kheiri, F Atyabi, F Dorkoosh. VIEW ABSTRACT

204  Preparation of PEGylated oligonucleotides by T4 ligase enzymatic mediated coupling. Presenter: G Pasut, Department of Pharmaceutical Sciences, University of Padua, Via Marzolo 5, 35131 Padua, Italy. Authors: A Sosic, M Pasqualin, B Gatto, G Pasut. VIEW ABSTRACT

205  Promotion of Bone Regeneration Using Gene Activated Collagen Matrices. Presenter: S D'mello, The University of Iowa, U.S.A.. Authors: S D'mello, S Elangovan, A Salem. VIEW ABSTRACT

207  RNA interference-mediated reversal of metallothionein-dependent cisplatin resistance using reducible poly(oligo-D-arginine). Presenter: H Kim, Hanyang University, Korea. Authors: H Kim, S Yong, J Chung, J Lee. VIEW ABSTRACT

208  siRNA Targeted Delivery to Ovarian Cancer Cells via Folate Conjugated Triblock Co-polymer. Presenter: S Jones, Wayne State University Cancer Biology Graduate Program, U.S.A.. Authors: S Jones, O Merkel. VIEW ABSTRACT

210  Span nanoparticles as more efficient vectors for in vivo transfection of photoreceptors and RPE cells than adeno-associated viral vectors. Presenter: A Pensado, University of Santiago de Compostela, Spain. Authors: A Pensado, B Seijo, B De La Cerda, L Valdés-Sánchez, S S Bhattacharya, A Sánchez, F J Diaz-Corrales. VIEW ABSTRACT

211  Spectroscopic characterization of the formation and binding affinities of the PLL- and PEI- polymer-DNA polyplexes. Presenter: M Yliperttula, Division of Pharmaceutical Biosciences, Centre for Drug Research, FI- 00014 University of Helsinki, Finland. Authors: T Ketola, E S Lisitsyna, M Hanzlikova, C J Bishop, E Morin-Pickardat, F Winnik, J Green, H Lemmetyinen, A Urtti, M Yliperttula, E Vuorimaa-Laukkanen. VIEW ABSTRACT

212  Survivin-targeted siRNA loaded polysaccharide nanoparticles for anti-tumor therapy in mice. Presenter: Z Gao, Chinese Academy of Medical Sciences, China. Authors: Z Gao, F Yang, W Huangwei, M Jin. VIEW ABSTRACT

214  Targeted deliver therapeutic siRNA into activated T cell by Tf-ss-PEI conjugate for therapy of asthma  . Presenter: y xie, Wayne state University, U.S.A.. Authors: y xie, N Kim, V Nadithe, A Thakur, L G Lum, D J Bassett, O M Merkel. VIEW ABSTRACT

215  The Absence of CpG sequences in Plasmid DNA-Chitosan Polyplexes Increases Transfection Efficiencies and Reduces Inflammatory Responses in Murine Lungs. Presenter: A Wongrakpanich, College of Pharmacy, University of Iowa, U.S.A.. Authors: A Wongrakpanich, A Adamcakova-Dodd, V B Joshi, K Mapuskar, S M Geary, D R Spitz, P S Thorne, A K Salem. VIEW ABSTRACT

216  The Effect of Serum in Culture on RNAi Efficacy through Modulation of Polyplexes Size. Presenter: J Liu, Chinese Academy of Medical Sciences & Peking Union Medical College, China. Authors: J Liu, W Zhang, J Meng, H Xu. VIEW ABSTRACT

217  Using a High Content Screening System to Investigate the Relationship between Transfection Efficiency and Polyethylenimine/pDNA complex localization. Presenter: A Wongrakpanich, College of Pharmacy, University of Iowa, U.S.A.. Authors: A Wongrakpanich, M Wu, A K Salem. VIEW ABSTRACT

Breakthrough Technologies     [RETURN TO TOP]

220  Customized Biomaterials to Enhance Gene Therapy by Augmenting Retention of Target Proteins. Presenter: I N Aguilar, Department of Biomedical Engineering Cornell University, U.S.A.. Authors: I N Aguilar, S B Trippel, Shi, L J Bonassar. VIEW ABSTRACT

221  Cytotoxic Synthetic Chemical Polymers as a New Class of Anticancer Agents. Presenter: C Wang, University of Minnesota, U.S.A.. Authors: W Ji, D Panus, W Han, C Wang. VIEW ABSTRACT

222  Developing a High-Throughput Drug Screening Platform Using Droplet Microfluidics. Presenter: S Mirza, post doctoral fellow, U.S.A.. Authors: A Basu, S Mirza, I Miroshnyk, L Mazutiz, D Weitz. VIEW ABSTRACT

223  Diffusion of fluorescent insulin from an acrylic derivatised dextran-concanavalin A gel in an implantable closed loop insulin delivery device. Presenter: D Jacob, De Montfort University, United Kingdom. Authors: D Jacob, M Taylor, P Tomlins, T S Sahota, E Jaroszkiewicz. VIEW ABSTRACT

224  Drug Releasing Antibacterial Scaffold for Tissue Engineering and Drug Delivery Application. Presenter: U Nayanabhirama, Research Directorate, Manipal University, India. Authors: M Amirthalingam, N Kasinathan, U Nayanabhirama. VIEW ABSTRACT

225  Foaming via melt extrusion for improving the grindability of extrudates and dissolution rate of oral dosages. Presenter: N Ioannidis, PPI/NJIT, U.S.A.. Authors: C Martin, N Ioannidis, C Gogos, G Terife. VIEW ABSTRACT

226  Inkjet Printing Guided Micro-patterned Neovessel Formation. Presenter: M H Rich, University of Illinois, U.S.A.. Authors: M H Rich, M K Lee, J Jeong, K Baek, N Yonet-Tanyeri, L Millet, R Bashir, H Kong. VIEW ABSTRACT

227  Lubricin-Mimetics to Prevent Progression of Osteoarthritis. Presenter: M Tan, Cornell University, U.S.A.. Authors: M Tan, K Samaroo, M Demange, M Sisto, X Deng, S Rodeo, L Bonassar, D Putnam. VIEW ABSTRACT

228  Mesoporous silica-based materials as delivery system for doxorubicin hydrochloride and metronidazole. Presenter: W Sawicki, Department of Physical Chemistry, Faculty of Pharmacy, Medical University of Gdansk, Poland. Authors: W Sawicki, K Czarnobaj, M Prokopowicz, A Szewczyk. VIEW ABSTRACT

229  Nerve-repair conduit formed of beaded PLLA fibers sustained-releasing nerve growth factor of native form. Presenter: F Wu, Shanghai Jiao Tong University, China. Authors: F Wu, Y Mu, M Qin, T Jin. VIEW ABSTRACT

230  Novel diagnostic device with enzyme-responsive beads for detection of wound infection. Presenter: N E Papen-Botterhuis, TNO, Netherlands. Authors: N E Papen-Botterhuis, A Heinzle, D Schiffer, I K Haaksman, R K Cremers, H B Lenting, G M Guebitz, E Sigl. VIEW ABSTRACT

231  pH-Responsive Fluorescence Polymer Probe for Tumor pH Targeting. Presenter: Y Hiruta, Keio University, Japan. Authors: Y Hiruta, T Funatsu, Y Maekawa, M Matsuura, T Okano, H Kanazawa. VIEW ABSTRACT

233  Self-assembling low molecular weight N-acyl nuceloside gelators. Presenter: K J Skilling, University of Nottingham, United Kingdom. Authors: K J Skilling, A Ndungu, T D Bradshaw, M Ashford, B Kellam, M Marlow. VIEW ABSTRACT

234  Spatial Control of Multimodal Microchannels in a Hydrogel . Presenter: M Lee, University of Illinois at Urbana-Champaign, U.S.A.. Authors: M Lee, M Rich, A Shkumatov, J Lee, H Kong. VIEW ABSTRACT

236  Validation of Multifunctional Surfaces for Tumor Cell Capture from Human Blood. Presenter: J Myung, University of Illinois at Chicago, U.S.A.. Authors: J Myung, K A Gajjar, R E Molokie, S Hong. VIEW ABSTRACT

Cells as Delivery Vehicles     [RETURN TO TOP]

102  Assembly and Characterization of a Cell-particle Hybrid System as a Potential Cancer Vaccine. Presenter: K K Ahmed, University of Iowa/college of pharmacy, U.S.A.. Authors: K K Ahmed, S M Geary, A K Salem. VIEW ABSTRACT

238  Hydrogel for Protein Repellency. Presenter: J Zheng, ShenYang Pharmaceutical University, China. Authors: J Zheng. VIEW ABSTRACT

746 Spontaneous Neural Differentiation of Human Mesenchymal Stem Cells by Multiwalled Carbon Nanotubes. Presenter: G. Hsiue, Chung Yuan University, Taiwan. Authors: Y. Chen, G. Hsiue. VIEW ABSTRACT

Controlled Release Applications in Food, Feed, and Beverages     [RETURN TO TOP]

241  IPP: Permeability, Stability & Toxicity. Presenter: J P Gleeson, University College Dublin, Ireland. Authors: J P Gleeson, J Heade, S M Ryan, D J Brayden. VIEW ABSTRACT

242  Starch-Pectin Based Delivery System for Ascorbic Acid. Presenter: Y Liu, University of Nebraska-Lincoln, U.S.A.. Authors: Y Liu, W S Ratnayake. VIEW ABSTRACT

Controlled Release of Actives in Consumer Products     [RETURN TO TOP]

106  PHBV Nanoparticles of FTY720 (Fingolimod): Drug Loading and Release Studies of a Water In-Soluble Drug. Presenter: F Dorkoosh, Associate Professor, Iran. Authors: L Rezaei, F Dorkoosh, R Dinarvand, M Amini. VIEW ABSTRACT

244  Controlled Release of Opiate Drugs Using Ion Exchange Resins. Presenter: A S Gehris, The Dow Chemical Company, U.S.A.. Authors: A S Gehris, J R Fisher, S Iuliano, J Hurry. VIEW ABSTRACT

246  Formulation and Characterization of niosomal carriers for topical application of (+)-catechin. Presenter: D Li, The University of Auckland, New Zealand. Authors: D Li, Z Wu, N Martini, J Wen. VIEW ABSTRACT

248  Injectable long-term control-released in situ gels of hydrochloric thiothixene for the treatment of schizophrenia. Presenter: C Xin, Shenyang Pharmaceutical University, China. Authors: C Xin, H Fei, W Yan, W Lihong. VIEW ABSTRACT

249  Moisture and Fragrance Release from Hydrogel Air Fresheners. Presenter: R M van Sleeuwen, Firmenich, Inc., U.S.A.. Authors: R M van Sleeuwen, A Nicolae, B MacDougall. VIEW ABSTRACT

Evaluation and Characterization of Controlled Release Products and Production Processes     [RETURN TO TOP]

251  A new injectable liquid crystal-forming system for on month delivery of Leuprolide. Presenter: Sung-Won An, Chong Kun Dang Pharmaceuticals Inc., South Korea. Authors: S Park, H Baik, J Ko, S An, M Ki. VIEW ABSTRACT

252  A novel intravaginal ring to deliver a unique combination microbicide, and a contraceptive for 90 days. Presenter: S Ugaonkar, The Population Council, U.S.A.. Authors: S Ugaonkar, A Wesenberg, J Wilk, S Seidor, O Mizenina, L Kizima, A Rodriguez, S Zhang, K Levendosky, G Calenda, M Aravantinou, J Kenney, N Derby, A Gettie, J Blanchard, M Robbiani, N Teleshova, J Fernandez-Romero, T Zydo. VIEW ABSTRACT

253  A Robustness Study of an Extended-Release Tablet Formulation Using a Sample Kit of Hypromellose for Quality-by-Design Concept. Presenter: A Quadir, SE Tylose USA, Inc., U.S.A.. Authors: T Hoshino, S Obara, A Quadir, H Kokubo. VIEW ABSTRACT

254  A Synthetic P-IHDD - Based Compact Matrix System for Extended Drug Release: In vitro Characterization and In silico Release Prediction. Presenter: O A Adeleke, Council for Scientific and industrial research, pretoria, Southwest Africa. Authors: O A Adeleke, V Pillay, Y E Choonara, L C du Toit. VIEW ABSTRACT

255  A Thermosensitive Glycol Chitin Gel For The Vaginal Delivery of Progesterone: In vitro and In vivo Evaluation. Presenter: A Almomen, University of Utah, U.S.A.. Authors: A Almomen. VIEW ABSTRACT

256  Applying statistical process control in process development - Liposome manufacturing by sonication, high shear mixing and microfluidics. Presenter: E Kastner, Aston University / UCL, England. Authors: E Kastner, A J Ingham, Y Perrie. VIEW ABSTRACT

257  Assessing the Impact of HPMC Physical Properties and Powder Flow on Process Control During Direct Compression of Matrix Tablets. Presenter: K O Hewlett, The Dow Chemical Company, U.S.A.. Authors: T L Rogers, K O Hewlett, J Theuerkauf, K M Balwinski, M Kodam, G LaBella, N Knabe, L F Ruocco. VIEW ABSTRACT

258  Characteristics of Felodipine:HPMCAS Solid Dispersions: Dissolution Performance and Particle Size Effects . Presenter: J Mole, Sirius Analytical Inc., U.S.A.. Authors: J Mole, K Box, J Comer, R Taylor, B Stockton, G Butcher, D Matthews, R Ruiz. VIEW ABSTRACT

259  Characterization of HPMC and Polyox: TA. Presenter: M Brewster, Janssen Research and Development, Belgium. Authors: A Faure, G Verreck, R De Maesschalck, J Mensch, K Vanhoutte, M Brewster. VIEW ABSTRACT

260  Characterization of HPMC and Polyox:MRI. Presenter: M Brewster, Janssen Research and Development, Belgium. Authors: A Faure, G Verreck, R De Maesschalck, J Mensch, K Vanhoutte, B Segmueller, R Wechselberger, M Brewster. VIEW ABSTRACT

261  Comparative Dissolution Study of Telmisartan Tablets. Presenter: S Hwang, Yonsei University, South Korea. Authors: S Hwang, J Ahn, H Kang, I Song, S You. VIEW ABSTRACT

262  Comparison of Enteric Polymer Coated to Commercially Available Acid Resistant Capsules for Delayed Release Delivery. Presenter: A S Lambert, CoreRx, Inc., U.S.A.. Authors: M B Greene, A S Lambert, B Hilker. VIEW ABSTRACT

263  Design and in vitro evaluation of indomethacin buccal tablets. Presenter: O Esim, Gulhane Military Medical Academy, Department of Pharmaceutical Sciences, Ankara, 06010, TURKEY, Turkey. Authors: O Esim, A Savaser, C K Ozkan, C Tas, Y Ozkan. VIEW ABSTRACT

266  Designing Modified Release Tablet Formulation of Quetiapine Fumarate by Using Artificial Neural Network Programs. Presenter: Y Erginer, Istanbul University, Turkey. Authors: Y Erginer. VIEW ABSTRACT

267  Determining Loading of Ibuprofen on Mesoporous Silica Nanoparticles. Presenter: D J Burnett, Surface Measurement Systems, Ltd., U.S.A.. Authors: D J Burnett, R Smith, J Y Heng. VIEW ABSTRACT

268  Determining Solubility Parameters of Poloxamers by Experimental and Computational Methods. Presenter: D J Burnett, Surface Measurement Systems, U.S.A.. Authors: D J Burnett, A R Garcia, Y Lan, S Ali. VIEW ABSTRACT

269  Determining Surface Amorphous Content by Surface Energy Distribution Analysis. Presenter: D J Burnett, Surface Measurement Systems, Ltd., U.S.A.. Authors: D J Burnett, A R Garcia, R Smith, J Y Heng. VIEW ABSTRACT

270  Development and assessment of captopril loaded matrix-type pellets  . Presenter: R B Walker, Rhodes University, South Africa. Authors: R B Walker, S Y Mukozhiwa, S M Khamanga. VIEW ABSTRACT

271  Development and assessment of gastroretentive sustained release captopril tablets. Presenter: R B Walker, Rhodes University, South Africa. Authors: R B Walker, S Y Mukozhiwa, S M Khamanga. VIEW ABSTRACT

272  Development of Tissue Equivalent Phantoms for Improved In Vitro Characterization of In Situ Forming Drug Delivery Implants. Presenter: M Goss, Case Western Reserve University, U.S.A.. Authors: M Goss, H Zhou, A Exner. VIEW ABSTRACT

273  Dissolution Performance of Inhaled Product APIs in Simulated Lung Fluid Using Novel Low Volume Assays. Presenter: J Mole, Sirius Analytical Inc., U.S.A.. Authors: J Mole, K Box, J Comer, R Taylor, R Ruiz, A Linas, J Solandt, U Tehler. VIEW ABSTRACT

274  Effect of component of gel on E2 release. Presenter: Y Yang, Shenyang Pharmaceutical University, China. Authors: Y Yang, X Che, Y Gao, S Li. VIEW ABSTRACT

275  Effect of Polymer (Ethylcellulose), Plasticizer (Dibutyl Sebacate) and Curing Time on the Dissolution Rate of Multi-Layer Sustained Release Pellets. Presenter: C P Hollis, Catalent Pharma Solutions, U.S.A.. Authors: C P Hollis, C Conde, H Cocolas. VIEW ABSTRACT

276  Engineering in vitro three-dimensional tumor models by surface fabrication. Presenter: C S Shin, Purdue University, U.S.A.. Authors: C S Shin, A Ozcelikkale, B Han, K Park. VIEW ABSTRACT

277  Evaluation of a New Co-Processed Excipient for Orally-Disintegrating Tablets. Presenter: S Obara, SE Tylose USA, Inc., U.S.A.. Authors: Y Hirama, S Obara, A Quadir, N Maruyama. VIEW ABSTRACT

278  Formulation and characterization of antimicrobial chewing gum delivery of some herbal extracts for the treatment of periodontal diseases. Presenter: R Yadav, IES College of Pharmacy, India. Authors: R Yadav, A Sharma, S K Yadav. VIEW ABSTRACT

280  Formulation optimization of chitosan nanoparticles using experimental design. Presenter: A A Al-kinani, School of Pharmacy and Chemistry, Kingston University London, United Kingdom. Authors: A A Al-kinani, A Vangala, D P Naughton, B K Pierscionek, G Calabrese, R G Alany. VIEW ABSTRACT

283  In vitro release and theoretical modeling of a selection of formulations in modified mini-IDR™ holders. Presenter: E Ahnfelt, Uppsala University, Sweden. Authors: E Ahnfelt, E Sjögren, N Axén, H Lennernäs. VIEW ABSTRACT

285  In vivo evaluation of various formulation strategies for controlled release injectables of poorly soluble drugs. Presenter: J Meeus, University of Leuven, Belgium. Authors: J Meeus, D J Scurr, K Amssoms, P Annaert, M C Davies, C J Roberts, G Van den Mooter. VIEW ABSTRACT

286  Injectable doxorubicin thermosensitive hydrogels for localized cancer therapy. Presenter: H Jhan, Hua-Jing Jhan, Taiwan. Authors: H Jhan. VIEW ABSTRACT

287  Investigation of the Effect of Ethylcellulose Viscosity Variation Using QbD Sample, on the Acetaminophen Drug Release from Extended Release Multiparticulate  . Presenter: A R Rajabi-Siahboomi, Colorcon Inc., U.S.A.. Authors: R Y Mehta, J Teckoe, C Schoener, S Workentine, A R Rajabi-Siahboomi. VIEW ABSTRACT

288  In-Vivo Pharmacokinetic Study on Microemulsions by Phase Transition into Liquid Crystal and Coarse Emulsion in-situ. Presenter: K K Singh, School of Pharmacy and Biomedical Sciences, University of Cental Lancashire, Preston, United Kingdom. Authors: K K Singh, D T Desai. VIEW ABSTRACT

289  Noninvasive Evaluation of the Role of Polymer Molecular Weight on Erosion and Degradation of In Situ Forming Implants. Presenter: H Zhou, Department of Biomedical Engineering, U.S.A.. Authors: H Zhou, A Gawlick, A Exner. VIEW ABSTRACT

290  Novel Crush Resistant Microspheres: Applications for Enhanced Safety and Abuse Deterrence. Presenter: A B Fleming, Collegium Pharmaceutical, Inc, U.S.A.. Authors: A B Fleming, S Saim, S P Mayock, R K Varanasi. VIEW ABSTRACT

291  Optimization and Manufacturing of Lipid-Surfactant Nanoparticles: Implication on Physicochemical Properties and Drug Release. Presenter: M Rodriguez Colon, University of Puerto Rico, Medical Sciences Campus, U.S.A.. Authors: Authors: M Rodriguez Colon, E S Ghaly. VIEW ABSTRACT

293  Physico-mechanical Characterization and Evaluation of Directly Compressible Grades of Hypromellose. Presenter: D Tewari, Ashland Specialty Ingredients, U.S.A.. Authors: D Tewari, J Lian, T Durig. VIEW ABSTRACT

294  Pilot Scale Evaluation of METHOCEL™ DC2 for Robust Matrix Tablet Manufacture by Direct Compression. Presenter: G LaBella, Colorcon Inc, U.S.A.. Authors: G LaBella, J Theuerkauf, T L Rogers. VIEW ABSTRACT

295  Predictive Modeling and Validation of Tamoxifen Release from EVA Copolymers. Presenter: B Zhang, Celanese International, U.S.A.. Authors: B Zhang, K Anderson, K Sledziewski, B Braker, J McConnell, M Grieco, A Loxley. VIEW ABSTRACT

296  Preparation and characterization of alginate-based ferrogels. Presenter: H Kim, Hanyang University, South Korea. Authors: H Kim, H Park, K Lee. VIEW ABSTRACT

297  Preparation of Orally Disintegrating Tablets Containing Taste-Masked Coated Pellets. Presenter: M Fukasawa, Shin-Etsu Chemical Co., Ltd., Japan. Authors: M Fukasawa, T Yokosawa, S Obara, H Kokubo. VIEW ABSTRACT

298  QbD Small Scale Process Development and Prediction of an Matrix-Type Extended Release Tablet. Presenter: X Guo, Prinston Pharmaceutical Inc., U.S.A.. Authors: F Cai, Z Yu, H Zhou, X He, H Zhao, H Chen, R Luo, L Shi, M Wang, J Du, X Guo. VIEW ABSTRACT

299  Quantification of PEG surface coverage-density on polymeric nanoparticle and its effect on physico-chemical properties. Presenter: J Rabanel, Faculté de pharmacie, Uinversité de Montréal, Canada. Authors: J Rabanel, S Alsharif, X Banquy, P Hildgen. VIEW ABSTRACT

300  Rapid formulation development and clinical testing strategies in the development of controlled release products. Presenter: M Paterson, Quotient Clinical, United Kingdom. Authors: J McDermott, P Scholes, M Paterson. VIEW ABSTRACT

303  Sustained Delivery of Hydroxychloroquine from a Polyether Urethane Intravaginal Ring. Presenter: Y Chen, Laboratory for Drug Delivery and Biomaterials, Faculty of Pharmacy, University of Manitoba, Canada. Authors: Y Chen, K R Fowke, E A Ho. VIEW ABSTRACT

305  Synthesis, Characterization and Cytotoxicity Study of Poly(ethylene glycol)-Hexamethylene Sebacamide Biopolymer. Presenter: H S Al-Lami, Professor, Iraq. Authors: H S Al-Lami. VIEW ABSTRACT

306  Tablet Compaction of Lipid Nanoparticles: Impact on Physicochemical Properties and Phase Transformation. Presenter: Maria Laboy-Cruz, University of Puerto Rico, Medical Sciences Campus, U.S.A.. VIEW ABSTRACT

307  The Effect of Polymeric Micelles Concentrations on Two Fluorphores by Fluorescence Resonance Energy Transfer. Presenter: J Liaw, School of Pharmacy, Taipei Medical University, Taiwan. Authors: F Hsaio, J Liaw. VIEW ABSTRACT

308  The Influence of Manufacturing Method on Physical Properties and Drug Release from Push Pull Osmotic Pump (PPOP) Products. Presenter: G LaBella, Colorcon Inc, U.S.A.. Authors: G LaBella, M Rane, P Patel. VIEW ABSTRACT

Innovations in Micro- and Nano-Based Delivery     [RETURN TO TOP]

309  A new Poly (ethylene oxide)/ACV nanofibrous matrix as a potential vaginal drug delivery system. Presenter: F A Dorkoosh, Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran., Iran. Authors: F A Dorkoosh. VIEW ABSTRACT

310  A Novel Approach to Detection of Low-Concentration Biomarkers . Presenter: L R Khoury, Ben-Gurion University of the Negev, Israel. Authors: L R Khoury, R Goldbart, T Traitel, J Kost, G Enden. VIEW ABSTRACT

311  A PEGylated liposome formulation of Tofacitinib targets a site of inflammation and enhances therapeutic efficacy in a mouse calvarial osteolysis model. Presenter: x wei, University of Nebraska Medical Center, U.S.A.. Authors: x wei, J Wu, R Ke, H Yuan, Y Zhang, P Purdue, S R Goldring, D Wang. VIEW ABSTRACT

312  A Pure Titanium/Titania Implant for Tunable Zero-Order Drug Delivery. Presenter: K E Fischer, Nano Precision Medical, U.S.A.. Authors: K E Fischer, A H Duong, W G Fischer, T Yoshie, J Peterson, A D Mendelsohn. VIEW ABSTRACT

313  A Sheet-Shaped Poly (ethylene glycol)-Modified Chitosan HydrogelContaining Crosslinkable Polymeric Micelles for Wound Dressing and Drug Release. Presenter: C Yoshida, Tokyo University of Agriculture and Technology, Japan. Authors: C Yoshida, Y Murakami. VIEW ABSTRACT

316  Amylose Based Glyco Star Copolymers: A Platform for New Glyco-biomaterials. Presenter: T Nishimura, Kyoto University, Japan. Authors: T Nishimura, S Mukai, S Sawada, K Akiyoshi. VIEW ABSTRACT

317  Amylose complexes intended to design of controlled drug delivery systems. Presenter: B F Cury, 1School of Pharmaceutical Sciences – Univ Estadual Paulista – UNESP, Brazil. Authors: F M Carbinatto, A B Meneguin, B F Cury. VIEW ABSTRACT

318  Antibacterial property of novel coating. Presenter: J Wu, School of Stomatology, Fourth Military Medical University, China. Authors: J Wu, Y Cheng, B Gao. VIEW ABSTRACT

319  Anti-Oxidative Bilirubin Nanovesicles Show Potential for Use in Anti-Inflammation Therapy. Presenter: Y Lee, Korea Advanced Institute of Science and Technology, South Korea. Authors: Y Lee, S Lee, H Kim, S Jon. VIEW ABSTRACT

320  Aspartic Acid Based Peptides Modify on PLGA-PEG Nanoparticles for Bone Targeting. Presenter: C Lin, Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Taiwan. Authors: C Lin, Y Fu, H Wang, S Wu, C Wang. VIEW ABSTRACT

321  Beads of gellan gum and gellan gum/pectin: comparative study of mucoadhesion and dissolution properties. Presenter: B F Cury, 1School of Pharmaceutical Sciences, Universidade Estadual Paulista - UNESP, Brazil. Authors: F G Prezotti, F I Boni, L N Pedreiro, B F Cury. VIEW ABSTRACT

322  Biodegradable particles for co-delivery of doxorubicin and CpG ODN oligonucleotides as an improved therapy for tumors. Presenter: V Joshi, University of Iowa, U.S.A.. Authors: V Joshi, A Wongrakpanich, A Salem. VIEW ABSTRACT

323  Branched Glycerol-Modified Liposomes as a New Candidate of Drug Carriers. Presenter: Y Kawashima, Kobe University, Japan. Authors: Y Kawashima, T Ooya. VIEW ABSTRACT

324  Catechol-Containing Antioxidant Micelles for Anti-Angiogenic Therapy. Presenter: M Moriyama, Graduate School of Engineering, Osaka University, Japan. Authors: M Moriyama, S Metzger, M Ehrbar, A J van der Vlies, H Uyama, U Hasegawa. VIEW ABSTRACT

325  Cellular Interactions of Dendron Micelles Controlled by the Length of Hydrophilic Chains. Presenter: H Hsu, Department of Biopharmaceutical Sciences, University of Illinois at Chicago, Taiwan. Authors: H Hsu, R M Pearson, S Uddin, P Král, S Hong. VIEW ABSTRACT

327  Characterization and Pharmaceutical Evaluation of Antifungal Textiles. Presenter: M A Hossain, University of Montreal, Canada. Authors: M A Hossain, A Benhaddou, K Theberge, P Simard, M Raymond, J Leblond-Chain. VIEW ABSTRACT

328  Characterization of Functional Liposome with Tunable Surface Property and Cellular Uptake by Temperature Control. Presenter: J Wang, Keio University, Japan. Authors: J Wang, E Ayano, H Kanazawa, Y Maitani, T Okano. VIEW ABSTRACT

329  Chitosan-coated nanofibrous sheet including human growth factor for treating oral mucositis. Presenter: h yoo, Kangwon National University, Korea. Authors: h yoo. VIEW ABSTRACT

332  Controlled release by hydrogel dissipative properties. Presenter: M Nassajian Moghadam, PhD student, Switzerland. Authors: M Nassajian Moghadam, V Kolesov, H Klok, D P Pioletti. VIEW ABSTRACT

334  Core-shell anticancer drug LbL nanoformulation with protein resistant properties. Presenter: T Levchenko , Department of Pharmaceutical Sciences Northeastern University, U.S.A.. Authors: T Levchenko, T Shutava, P Pattekari, G Parekh, V Torchilin. VIEW ABSTRACT

335  Core-Shell Fibers for Zero-Order Intravaginal Drug Delivery of Hydrophilic Antiretrovirals. Presenter: C Ball, University of Washington, U.S.A.. Authors: C Ball, K A Woodrow. VIEW ABSTRACT

336  Design and optimization of Teriparatide loaded PHBV/PLGA blend nanoparticles. Presenter: F A Dorkoosh, Department of Pharmaceutics,Tehran University of Medical Science, Iran. Authors: N Bahari Javan, M Amini, H Akbari Javar, F A Dorkoosh. VIEW ABSTRACT

337  Design and Preparation of a Polymeric H2S Donor. Presenter: A J van der Vlies, Osaka University, Japan. Authors: A J van der Vlies, U Hasegawa. VIEW ABSTRACT

338  Design and use of silica-containing redox nanoparticles, siRNP, for protection of encapsulating peritoneal sclerosis. Presenter: Y Nagasaki, University of Tsukuba, Japan. Authors: Y Nagasaki, T Yaguchi, T Matsumura, T Yoshitomi, Y Ikeda, A Ueda, A Hirayama. VIEW ABSTRACT

339  Development and characterization of dexamethasone-loaded microsphere formulations for long-term continuous release. Presenter: B Gu, University of Connecticut, U.S.A.. Authors: B Gu, Y Wang, D J Burgess. VIEW ABSTRACT

340  Development and Optimization of PLGA Nanoparticles as a Carrier System for Oral Delivery of Gemcitabine. Presenter: G Chen, School of Pharmacy, Faculty of Medical and Health Sciences, University of Auckland, New Zealand. Authors: G Chen. VIEW ABSTRACT

341  Development of Liquid Crystal Systems from Meglumine-Based Supra-Amphiphile for Topical Delivery of Drugs. Presenter: M Fonseca, Institute of Chemistry, UNESP, Araraquara, SP, 14800-060, Brazil, Brazil. Authors: A Souza, M Fonseca, L Miziara, S Kurokawa, D Cassimiro, C Kiill, M Jakubic, M Gremião, V Sarmento, C Ribeiro. VIEW ABSTRACT

342  Development of Novel Biodegradable and Biocompatible Poly(diaminosulfide) Microparticles as a Chemotherapeutic Drug Delivery System. Presenter: S D'mello, The University of Iowa, U.S.A.. Authors: S D'mello, J Yoo, N Bowden, A Salem. VIEW ABSTRACT

343  Development of Photothermally-Active Gold Shell-Coated Lipid Nanoparticles. Presenter: J Nam, University of Michigan, U.S.A.. Authors: J Nam, C J Monroe, J J Moon. VIEW ABSTRACT

344  Development of Temperature-Sensitive Hydrogel Nanoparticles for Targeted Chemotherapy. Presenter: T Shirakura, Biophysics and Chemistry, The University of Michigan, 930 N. University Avenue, Ann Arbor, MI 48109, U.S.A.. Authors: T Shirakura, A Ray, T J Kelson, R Kopelman. VIEW ABSTRACT

345  Dithiolethione-Bearing Polymeric Micelles for Hydrogen Sulfide-Based Therapy. Presenter: U Hasegawa, Osaka University, Japan. Authors: A J van der Vlies, U Hasegawa. VIEW ABSTRACT

346  Drug-Induced Nanocarrier Assembly for the Delivery of Nucleotides and Nucleotide Analogues. Presenter: H Hillaireau, Institut Galien Paris-Sud, Univ. Paris-Sud/CNRS, France. Authors: H Hillaireau, G Giacalone, A Bochot, E Fattal. VIEW ABSTRACT

347  Dual stimuli-responsive antioxidant polymer nanoparticles as therapeutics for oxidative stress-associated diseases. Presenter: D Lee, Chonbuk National University, Korea. Authors: D Lee, W You. VIEW ABSTRACT

348  Effect of Formulation Process Parameters on the Development of Nalbuphine HCl-Loaded Poly D,L-lactide-co-glycolide (PLGA) Microparticles. Presenter: S D'mello, The University of Iowa, U.S.A.. Authors: S D'mello, A Salem. VIEW ABSTRACT

350  Encapsulation of insulin peptides in liposomes for preventing  type 1 diabetes. Presenter: M Cano-Sarabia, Instituto Catalan de Nanotecnologia - ICN2, Spain. Authors: M Cano-Sarabia. VIEW ABSTRACT

351  Enhanced Apoptosis Induction by Bortezomib loaded in Liposomal Nanocarriers: A Comparison between Cationic and Ceramide Liposomes. Presenter: M D Joshi, Midwestern University, U.S.A.. Authors: G Park, J Pichlik, A Gilchrist, M D Joshi. VIEW ABSTRACT

352  Enhancement of Cytotoxic and Antineoplastic Activities of Doxorubicin via Vitamin C Co-delivered by Multi-layered Microparticles. Presenter: C Wang, National University of Singapore, Singapore. Authors: P Davoodi, C Wang, M Srinivasan. VIEW ABSTRACT

353  Evaluation of mucoadhesiveness of micro/nano particles containing zidovudine. Presenter: B F Cury, School of Pharmaceutical Sciences UNESP, Brazil. Authors: L N Pedreiro, B F Cury, M D Gremião. VIEW ABSTRACT

355  Fabrication of Nanogel-Crosslinked Porous Gels for Tissue Engineering Applications. Presenter: Y Hashimoto, Graduate School of Engineering, Kyoto University, Japan. Authors: Y Hashimoto, S Mukai, S Sawada, K Akiyoshi. VIEW ABSTRACT

357  Formulation and Characterization of Niacin Loaded PLGA-Based Nanoparticles. Presenter: D L Cooper, East Tennessee State University, U.S.A.. Authors: J A Carmical, D L Cooper, S Harirforoosh. VIEW ABSTRACT

359  Formulation development and evaluation of nanoparticles for sustained delivery of levodopa- dendrimer conjugate for treatment of Parkinson’s disease. Presenter: N Mulla, Mercer University, U.S.A.. Authors: N Mulla, S Singh. VIEW ABSTRACT

360  Freeze-Dried Nanocrystalline Cellulose Derived from Water Sugar-Cane Bagasse as a Novel Tablet Excipient. Presenter: A A El-Ashmawy, National Research Centre, Cairo, 12311, Egypt, Egypt. Authors: L H Emara, A A El-Ashmawy, N F Taha, K El-Shaffei, S Mahdey, H El-Kholly. VIEW ABSTRACT

362  Growth Factor-Carrying Hybrid Hydrogel/Nanogel Composite for the Treatment of Urethral Incontinence. Presenter: J Son, Ajou University, Korea. Authors: K Park, J Son, J Choi, I Kim, J Lee, K Park. VIEW ABSTRACT

364  Hsp16.5 Protein Nano-Cages Conjugated Magnetic Resonance Contrast Agents with High Efficient Relaxivity Properties  . Presenter: T Kawano, Innovation Center for Medical Redox Navigation, Kyushu university, Japan. Authors: T Kawano, M Murata, P Jing-Shu, S Narahara, N Hamano, K Ohuchida, M Hashizume. VIEW ABSTRACT

365  Hyaluronate - Gold Nanoparticle / Tocilizumab Complex for Combination Therapy of Rheumatoid Arthritis. Presenter: H Lee, POSTECH, South Korea. Authors: H Lee, M Lee, S Hahn. VIEW ABSTRACT

366  Hyaluronic Acid Nanoparticles for Delivery of ?-Secretase inhibitor. Presenter: R Heo, Sungkyunkwan University, Korea. Authors: R Heo, J Park, S Son, J Jeon, J Park. VIEW ABSTRACT

367  Hydrogel nanoparticles for delivery of short cationic antimicrobial peptides. Presenter: J J Water, University of Copenhagen, Denmark. Authors: J J Water, M J Maltesen, H Franzyk, C Foged, H M Nielsen. VIEW ABSTRACT

368  Hydrophobic Pheophorbide A Physically Loaded Bioreducible Poly(ethyleneimine)s : Preparation, Characterization, and Light-induced Cytotoxicity. Presenter: H Cho, The Catholic University of Korea, South Korea. Authors: H Cho, L Li, Y Bae, K Huh, H Kang. VIEW ABSTRACT

369  Imaging of Vascular-Injured Tissue by Liposomal Quantum-Dots  . Presenter: G Aizik, Institute for Drug Research, Faculty of Medicine and the Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Israel. Authors: G Aizik, N Waiskopf, N Koroukhov, U Banin, G Golomb. VIEW ABSTRACT

370  Impact of ions on double emulsions systems (W/O/W) stabilized by amphiphilic block copolymer. Presenter: Y Zhang, Shenyang Pharmaceutical University, China. Authors: Y Zhang, X Tang. VIEW ABSTRACT

371  Implantable Pump Actuated by Static Magnetic Field for On-demand Drug Delivery. Presenter: S Lee, Interdisciplinary Program in Bioengineering, College of Seoul National University, South Korea. Authors: Y Choy, S Lee. VIEW ABSTRACT

372  Increased in-vitro release time of poorly soluble drugs loaded into injectable crosslinked hyaluronic acid hydrogel formulations. Presenter: O M Dall, Mr., Denmark. Authors: O M Dall, M J Maltesen. VIEW ABSTRACT

373  Inhibition of bovine lactoferrin proteolysis in luminal contents and mucosal homogenates from rat intestine. Presenter: J Wen, School of Pharmacy, University of Auckland, New Zealand. Authors: J Wen. VIEW ABSTRACT

374  Insulin nanoparticles-containing emulsion for Oral Delivery of Insulin. Presenter: A J Ribeiro, University of Coimbra, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal, Portugal. Authors: M A Lopes, F J Veiga, B A Vieira, L M Cabral, A J Ribeiro. VIEW ABSTRACT

375  Insulin-loaded gellan microcapsules coated with resistant starch/pectin films: Morphology and mucoadhesive properties. Presenter: A B Meneguin, Faculty of Pharmaceutical Sciences – UNESP, Brazil. Authors: A B Meneguin, B S Cury. VIEW ABSTRACT

376  Intratympanic Injection Drug Delivery System for Extended Steroid Delivery to the Inner Ear. Presenter: N Dormer, Orbis Biosciences, Inc., U.S.A.. Authors: N Dormer, D Dumbauld, C Berkland. VIEW ABSTRACT

377  Large Scale Production of Cosmetic Hesperidin Nanocrystals by smartCrystal® Technology. Presenter: S Staufenbiel, Free University of Berlin, Germany. Authors: R Chen, C M Keck, S Staufenbiel, R H Müller. VIEW ABSTRACT

378  Liposomal system designed for the sustained release of ropivacaine    . Presenter: C M Silva, Unicamp, Brazil. Authors: C M Silva, B R Casadei, V A Damasio, M A Braga, C M Cereda, E de Paula. VIEW ABSTRACT

379  Magnetically Decorated Multi-Walled Carbon Nanotubes as Dual MRI and SPECT Contrast Agents. Presenter: K T Al-Jamal, King's College London, United Kingdom. Authors: K T Al-Jamal. VIEW ABSTRACT

380  Mechanical and Bioadhesive Behavior of Hexagonal Liquid Crystals From Meglumine-Based Supra-Amphiphile For Topical Drug Delivery Systems. Presenter: A R Souza, Institute of Chemistry, UNESP, Araraquara, Brazil. Authors: A R Souza, C P Kiill, L Miziara, S S Kurokawa, M Fonseca, D L Cassimiro, M A Jakubic, M D Gremião, C A Ribeiro. VIEW ABSTRACT

382  Metformin hydrochloride-loaded liposomes: a formulation study. Presenter: J O Eloy, University of São Paulo - College of Pharmaceutical Sciences of Ribeirao Preto, Brazil. Authors: J O Eloy, G L Raspantini, R Petrilli, J M Marchetti. VIEW ABSTRACT

383  Microwave-assisted Synthesis of Functionalized SiO2 Nanoparticles  . Presenter: J M Cornejo-Bravo, Universidad Autónoma de Baja California, Mexico. Authors: J M Cornejo-Bravo, E M Islas-Almanza, K A Espinoza-Dueñas, I A Rivero-Espejel. VIEW ABSTRACT

384  Molecular Size and Binding Affinity Influence Effectiveness of Ultrasound-Microbubble Mediated Drug Delivery. Presenter: J Roberts, GE Global Research, U.S.A.. Authors: J Roberts, M Butts, J Castle, B Johnson, B Kandapallil, M Marino, D Mills, K Wallace. VIEW ABSTRACT

387  Multi-Responsive Nanogels Based on Hyperbranched Polyglycerol. Presenter: A Sousa-Herves, Institut für Chemie und Biochemie, FU Berlin, Germany. Authors: A Sousa-Herves, S Wedepohl, M Calderón. VIEW ABSTRACT

388  Nanocrystal Formulation of Lercanidipine by Simple Evaporative Antisolvent Technique. Presenter: N Udupa, Manipal University, India. Authors: N Udupa, A D Chonkar, J Venkata Rao. VIEW ABSTRACT

389  Nanoparticles as a Promising Delivery System to Improve Hepatitis C Treatment. Presenter: Y M Abo-zeid, School of Pharmacy, University of Nottingham, Nottingham, United Kingdom. Authors: Y M Abo-zeid, R A Urbanowicz, A W Tarr, W L Irving, B J Thomson, M C Garnett. VIEW ABSTRACT

390  Novel Encapsulation of Arsenic Trioxide into Polymeric Micelles. Presenter: Q Zhang, University of Alberta, Canada. Authors: Q Zhang, M R Vakili, A Lavasanifar, X C Le. VIEW ABSTRACT

391  Novel sheet-shaped materials in which polymeric micelles are dispersed for the sustained controlled release of proteins. Presenter: R Anzai, Tokyo University of Agriculture and Technology, Japan. Authors: R Anzai, Y Murakami. VIEW ABSTRACT

392  Optimization and Characterization of PACA Nanoparticles for Drug Delivery and Imaging. Presenter: R B Schmid, SINTEF Materials and Chemistry, Norway. Authors: Y Mørch, S Eggen, A Åslund, E Sulheim, S Snipstad, S F Borgos, W R Glomm, G Singh, C L Davies, P M Stenstad, R B Schmid. VIEW ABSTRACT

393  Pectinate Micro-/Nano-particles for Stabilization of Retinyl Palmitate. Presenter: H Kim, Chung-Ang University, Korea. Authors: H Kim, J Ro, K Park, P Khadka, J Lee. VIEW ABSTRACT

394  Phase-guided microencapsulation, a method to prepare sustained-release microspheres for structurally delicate protein drugs . Presenter: Z Hu, Shanghai Jiao Tong University, China. Authors: Z Hu, M Xu, T Jin. VIEW ABSTRACT

395  Photothermally controlled drug delivery using a funtionalized graphene oxide. Presenter: W Kim, POSTECH, Korea. Authors: H Kim, I Park, M Jang, T Kim, W Kim. VIEW ABSTRACT

397  Poly(lactide-co-glycolide) Microspheres for MRI-Monitored Delivery of Sorafenib Locally to Liver Tumors. Presenter: J Chen, Northwestern University, Department of Chemical and Biological Engineering, U.S.A.. Authors: J Chen, S B White, K R Harris, J W Yap, R J Lewandowski, L D Shea, A C Larson. VIEW ABSTRACT

398  Polycation-Shielded Calcium/Fludarabin Phosphate Nanocomplexes: Preparation, Characterization, and In Vitro Anti-Tumor Effects. Presenter: D Cho, Department of Pharmacy, The Catholic University of Korea, Korea. Authors: D Cho, Y Choi, S Moon, D Lee, Y Bae, H Kang. VIEW ABSTRACT

399  Polycation-Shielded Calcium/Nucleotide Nanocomplexes: Preparation, Characterization, and Enhanced Cell Survival. Presenter: Y Choi, Department of Pharmacy, The Catholic University of Korea, Bucheon, Gyeonggi-do 420-743, Republic of Korea, Korea. Authors: Y Choi, D Cho, J Kim, D Lee, Y Bae, H Kang. VIEW ABSTRACT

400  Polysaccharide Nanogel-Hybrid Nanofibers by Electrospinning. Presenter: A Shimoda, Kyoto University, Japan. Authors: A Shimoda, S Mukai, S Sawada, Y Chen, K Akiyoshi. VIEW ABSTRACT

401  Preparation and characteristic of nanogel-cross-linked microsphere. Presenter: Y Tahara, Department of polymer chemisty, Japan. Authors: Y Tahara, S Mukai, S Sawada, Y Sasaki, K Akiyoshi. VIEW ABSTRACT

402  Preparation and Characterization of Magnolol Loaded Nano-Micro-Particle Complexes. Presenter: M Shen, National Taiwan University of Science and Technology, Taiwan. Authors: M Shen, C Chou, C Chou, T Tsai, C Kao. VIEW ABSTRACT

403  Preparation and evaluation of Pingyangmycin-loaded chitosan thermogels for vascular malformations therapy. Presenter: F Chen, Shenyang Pharmaceutical University, China. Authors: F Chen, W Pan, X Qin. VIEW ABSTRACT

404  Preparation and Pharmacological Evaluation of Uniform-sized Drug-loaded PLGA Microspheres by SPG Membrane Emulsification. Presenter: J Wu, Institute of Process Engineering, Chinese Academy of Sciences, China. Authors: J Wu. VIEW ABSTRACT

405  Preparation of a Vitamin E-based Polymeric Micelle for Cancer Therapy. Presenter: T Yamazaki, Kobe University, Japan. Authors: T Yamazaki, T Ooya. VIEW ABSTRACT

406  Preservation of Oral Nanosuspensions with Food Preservatives. Presenter: S Staufenbiel, FU Berlin - Institute of Pharmaceutics, Biopharmaceutics & NutriCosmetics, Germany. Authors: G B Romero, S Staufenbiel, C M Keck, R R Müller. VIEW ABSTRACT

407  Production of highly loaded Vitamin K1 nanostructures lipid carriers (NLC) against couperosis. Presenter: R Müller, Freie Universität Berlin, Institute of Pharmacy – Department of Pharmaceutics, Biopharmaceutics & NutriCosmetics, Germany. Authors: S Pyo, C Keck, R Müller. VIEW ABSTRACT

410  SCIO-469 loaded Microparticles for Osteoarthritis treatment: fluorescence imaging and drug delivery. Presenter: P Maudens, School Pharmaceutical Sciences, University of Geneva, University of Lausanne, 1211 Geneva, Switzerland. Authors: P Maudens, O Jordan, E Allémann. VIEW ABSTRACT

412  Self-assembling hyaluronate-based polyelectrolyte nanocomplexes for oral insulin delivery. Presenter: S Sladek, University College Dublin, Ireland. Authors: S Sladek, L Tajber, D J Brayden. VIEW ABSTRACT

413  Silicone embedded nanogels for prolonged resistance against biofilm formation. Presenter: S L Steffensen, Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark. Authors: S L Steffensen, M H Vestergaard, M G Jensen, M Alm, H Franzyk, H M Nielsen. VIEW ABSTRACT

414  Size-Tuneable Biodegradable Polymeric Nanoparticles for Controlled Drug Delivery . Presenter: A S Basra, The University of Nottingham, United Kingdom. Authors: A S Basra, J W Aylott, P M Williams. VIEW ABSTRACT

416  Sugar-based Amphiphiles for Drug Delivery: Library Synthesis and Phase Characterization. Presenter: G C Feast, CSIRO, Australia. Authors: G C Feast, T Lepitre, O E Hutt, X Mulet, C E Conn, C J Drummond, P Savage. VIEW ABSTRACT

417  Surface design of thermoresponsive core-corona type nanospheres with well-defined corona layer for regulation of protein adsorption. Presenter: T Matsuyama, Tokyo University of Science, Japan. Authors: T Matsuyama, T Asoh, A Kikuchi. VIEW ABSTRACT

419  Sustained Release of TGF-ß from Biodegradable 3-Dimentional fibrous Poly(L-lactic acid) Scaffold for Cartilage Regeneration. Presenter: H Kyung, Ewha Womans University, South Korea. Authors: H Kyung, S Lee. VIEW ABSTRACT

420  Synthesis of Biocompatible Nanogels of N-isopropylacrylamide and Carboxyalkyl Methacrylates by Soapless Emulsion Polymerization . Presenter: D A Castro-Vidal, Universidad Autónoma de Baja California, Mexico. Authors: D A Castro-Vidal, B M Lara-Molinero, A Serrano-Medina, J M Cornejo-Bravo. VIEW ABSTRACT

421  The Application of a Fluorescent Pre-Labelling Method for Evaluation of Exosome Biodistribution. Presenter: K A Howard, Aarhus University, Denmark. Authors: M F Ebbesen, K Bienk, B W Deleuran. VIEW ABSTRACT

422  Thermosensitive Liposomes Encapsulated in a Thermoresponsive Hydrogel for On-Demand Release: The Lipogel System. Presenter: G P Duffy, Tissue Engineering Research Group, Dept of Anatomy, The Royal of Surgeons in Ireland, Ireland. Authors: C Herron, H S O'Neill, C L Hastings, E Ruiz Hernández, A López-Noriega, H M Kelly, G Storm, W E Hennink, F J O'Brien, G P Duffy. VIEW ABSTRACT

424  Topical Drug Delivery of Nanoencapsulated Triclosan. Presenter: P Kakadia, University of Huddersfield, United Kingdom. Authors: P Kakadia, H E Larhrib, A M Smith, B R Conway. VIEW ABSTRACT

425  Triggered release of doxorubicin from temperature sensitive poly(N-(2-hydroxypropyl)-methacrylamide mono/dilactate) grafted liposomes. Presenter: M van Elk, Utrecht University, Netherlands. Authors: M van Elk, R Deckers, C Oerlemans, G Storm, T Vermonden, W E Hennink. VIEW ABSTRACT

426  Tuning semipermeability of polyion complex vesicles “PICsomes” by varying polycation side chains and crosslinking degree of polyion complex membrane. Presenter: O F Mutaf, Graduate School of Engineering, University of Tokyo, Japan. Authors: O F Mutaf, A Kishimura, Y Anraku, K Kataoka. VIEW ABSTRACT

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Innovations in Oral Drug Delivery     [RETURN TO TOP]

427  A Thorough Characterization of the Food Effect in Oral Drug Dissolution in the Stomach. Presenter: O Rezhdo, Northeastern University, U.S.A.. Authors: O Rezhdo, S Di Maio, D Budil, R L Carrier. VIEW ABSTRACT

429  Characterization of PVA and DMAB based Celecoxib Loaded Polymeric Nanoparticles. Presenter: D L Cooper, East Tennessee State University, U.S.A.. Authors: D L Cooper, S Harirforoosh. VIEW ABSTRACT

430  Comparing the Blood Glucose Profiles between Rectal and Oral Delivery of Insulin with Our Permeability Promoter A2032. Presenter: J Lee, Prafys Research Laboratory, U.S.A.. Authors: Y Byun, H Yoo, S Lee, C Chang, J Kim, E Kim, J Kim, H Kim, C Lee, J Lee, N Wang. VIEW ABSTRACT

431  Controlling the Release of Olanzapine by Preparation of selective Molecularly Imprinted Nano-particles as Drug Delivery System. Presenter: N Jafary Omid, Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran, Iran. Authors: N Jafary Omid, H Morovati, N Babanejad, S Maleki, F Dorkoosh. VIEW ABSTRACT

432  Development and Evaluation of novel floating-osmotic capsule for zero order delivery of extract of Andrographis paniculata Nees  . Presenter: P KILAMBI, L.J. INSTITUTE OF PHARMACY, AHMEDABAD, India. Authors: P KILAMBI, S SANJA, M Soniwala. VIEW ABSTRACT

433  Development and Operation of a New IntelliCap Fast Release System. Presenter: J Shimizu, Medimetrics Personalized Drug Delivery B.V., Netherlands. Authors: K Kerkhof, V Iordanov, J Shimizu, C Wanke, H Zou. VIEW ABSTRACT

434  Development of a Bilayer Zydis® Freeze Dried Orally Disintegrating Tablet. Presenter: L P Grother, Catalent, United Kingdom. Authors: L P Grother, L M Garrett, R McLaughlin. VIEW ABSTRACT

435   Development of a Bioequivalent Taste Masked Cetirizine HCl 10mg Zydis® Dosage Form using Cyclodextrin. Presenter: L P Grother, Catalent, United Kingdom. Authors: L P Grother, P Axe, L Dennis. VIEW ABSTRACT

436  Development of a Sachet Formulation of DRL282 Containing Delayed Release Pellets with Inactive Granules for NG Tube compliance and Bioequivalence. Presenter: D K Sahoo, 1, India. Authors: D K Sahoo, P D Chudiwal, N Chandra, V S Reddy, N Vaya, K K Venkatesh, P K Ghosh. VIEW ABSTRACT

437  Development of Redox Therapy for Periodontitis using Redox Injectable Gel  . Presenter: M Saita, Kanagawa Dental University, Japan. Authors: M Saita, J Kaneko, T Sato, S Takahashi, S Takahashi, R Kawamata, T Sakurai, M C Lee, N Hamada, K Kimoto, Y Nagasaki. VIEW ABSTRACT

438  Direct Visualization Shows that Conventional in vitro Capsule Dissolution Methods do not Reflect the in vivo Situation. Presenter: D Bar-Shalom, University of Copenhagen, Denmark. Authors: D Bar-Shalom, P Barbre Pedersen, P Vilmann, A D Müllertz. VIEW ABSTRACT

439  Dissolution Behavior of Cyclodextrin Molecular Inclusion Complexes of Artemether. Presenter: k C Ofokansi, University of Nigeria, Nsukka, Nigeria. Authors: k C Ofokansi, s Z Yahaya, S T Allagh, P G Bhatia. VIEW ABSTRACT

441  Drug layering with the aqueous polymer dispersion Kollicoat® SR 30 D for controlled release pellets. Presenter: R Bodmeier, Freie Universität Berlin, Germany. Authors: G Zoubari, A Dashevskiy, R Bodmeier. VIEW ABSTRACT

443  Enhancement of solubility and Bioavailability of a poorly water-soluble drug by Solid dispersion technique. Presenter: S S Patil, Scientist, Dr.Reddy’s Laboratories Limited, India. Authors: S S Patil, P Chellekkagari, M R, K T Gandhi. VIEW ABSTRACT

445  Estimating in vivo drug release from a new theophylline Compritol® 888 ATO matrix formulation using appropriate biorelevant test methods. Presenter: Y Cuppok-Rosiaux, Gattefossé SAS, France. Authors: N Fotaki, C Long, Y Cuppok-Rosiaux, D Marchaud, G Garbacz, S Lange, S Klein. VIEW ABSTRACT

446  Evaluation of Melt Techniques for the Manufacturing of Immediate Release (IR) Solid Dosage Forms. Presenter: G Loreti, Università degli Studi di Milano, Italy. Authors: G Loreti, A Melocchi, L Zema, M D Del Curto, S Salmaso, A Gazzaniga. VIEW ABSTRACT

448  Formulation and in vitro release of Telmisartan melt dispersion and tablets. Presenter: C J Kapadia, DGM Technical, Gattefosse India Pvt Ltd, India. Authors: C J Kapadia, M Venkataraman, M S Marwah, M S Nagarsenker, N J Farah. VIEW ABSTRACT

449  Formulation of Controlled Release Orally Disintegrating Tablets of a Water Soluble Compound. Presenter: A Kondappan, Scientist III, U.S.A.. Authors: A Kondappan, V S Rao Voleti, D Barbieri, J Vaughn. VIEW ABSTRACT

450  Formulation of Double-Layered Orally Disintegrating Microparticles Containing Desmopressin. Presenter: K Hwang, Sungkyunkwan University, South Korea. Authors: K Hwang, S Kim, S Seok, E Lee, J Kim, J Ha, C Park, Y Rhee, E Park. VIEW ABSTRACT

451  Formulation Approaches. Presenter: M E Brewster, Janssen Research & Development, Belgium. Authors: G Verreck, J Peeters, M E Brewster. VIEW ABSTRACT

453  Gabapentin And Flurbiprofen Combination Product: In Vitro Drug Release Comparison of Dome Matrix® Assembled System versus Three-layer Tablet. Presenter: A Rossi, Department of Pharmacy, University of Parma, Italy. Authors: A Rossi, G Pasotti, C Conti, S Barbieri, P Colombo. VIEW ABSTRACT

454  Gellan Gum Fluid Gels as Modified Release Oral Liquids. Presenter: M H Mahdi, University of Huddersfield, United Kingdom. Authors: M H Mahdi, A M Smith. VIEW ABSTRACT

455   Glucose-responsive double-layered nanogel for an oral delivery system. Presenter: D Lee, Korea Advanced Institute of Science and Technology, Korea. Authors: D Lee, Y Kim. VIEW ABSTRACT

456  HPMC Matrix Behaviour in Challenging Ionic Environments as a Function of Polymer Level. Presenter: L M Mason, University of Nottingham, United Kingdom. Authors: L M Mason, S R Pygall, J Burley, C Seiler, C D Melia. VIEW ABSTRACT

460  In vitro characterization of microcontainers as an oral drug delivery system . Presenter: L Hagner Nielsen, Department of Micro- and Nanotechnology, Technical University of Denmark, Denmark. Authors: L Hagner Nielsen, S Sylvest Keller, R Singh, J Jacobsen, B Anja, A Müllertz. VIEW ABSTRACT

461  In vitro enzymatic degradation of lipidified apomorphine. Presenter: N Borkar, University of Copenhagen, Denmark. Authors: N Borkar, R Holm, A Håkansson, A Müllertz, M Yang, H Mu. VIEW ABSTRACT

463  Investigating the In Vivo-In Vitro Correlation for the Effect of Kolliphor® EL, ELP and RH40 on the Bioavailability of Fenofibrate in Rats. Presenter: A Mullertz, Univ of Copenhagen, Denmark. Authors: R Berthelsen, R Holm, J Jacobsen, B Abrahamsson, J Kristensen, A Mullertz. VIEW ABSTRACT

465  Medicated Chewing Gums Loaded with Mucoadhesive Microparticles for Oral Candidiasis Treatment in Children. Presenter: B Conti, Department of Drug Sciences, University of Pavia, Italy. Authors: B Colzani, R Dorati, B Conti, T Modena, I Genta. VIEW ABSTRACT

466  Nanoporous magnesium carbonate as phase stabilizer of amorphous Ibuprofen. Presenter: P Zhang, Uppsala University, Sweden. Authors: P Zhang, J Forsgren, M Strømme. VIEW ABSTRACT

467  New Drug Delivery Technology Partnership Opportunity. Presenter: J. Bentley, Piedmont Pharmaceuticals, U.S.A.. Authors: J Bentley, S Rockett, E Barnett, B Clayton, T Ballard. VIEW ABSTRACT

470  Novel Core-Shell Protein Nanoparticles for Oral Drug Delivery. Presenter: M Alqahtani, South Dakota State University, U.S.A.. Authors: M Alqahtani. VIEW ABSTRACT

471  Novel Highly Effective Formulation for the Oral Treatment of Hyperphosphatemia: Nanocrystalline Maghemite. Presenter: R H Müller, Freie Universität Berlin, Department of Pharmaceutics, Germany. Authors: T Nguyen, R H Müller, J Schnorr, M Taupitz, S Wagner. VIEW ABSTRACT

472  Novel in situ preparation of sustained release oral delivery liquid crystalline nanoparticles. Presenter: B J Boyd, Monash Institute of Pharmaceutical Sciences, Australia. Authors: W Fong, C A Prestidge, A Hawley, B J Boyd. VIEW ABSTRACT

473  Optimization of Hot Melt Extrusion Parameters for Sphericity and Hardness on Polymeric Face-Cut Pellets. Presenter: J Park, Department of Pharmaceutics, School of Pharmacy, The University of Mississippi, U.S.A.. Authors: M A Repka, A S Alshetaili, X Feng, B K Almutairy, J Park, N Langley, K Kolter, A Gryczke. VIEW ABSTRACT

474  Oral nanomedicines for the treatment of parasitic diseases . Presenter: A Lalatsa, University of Portsmouth, United Kingdom. Authors: A Lalatsa, D R Serrano-Lopez, L Smith, M A Dea-Ayuela. VIEW ABSTRACT

475  PAMAM Dendrimer Based Oral Formulation Development For Colon Specific Delivery. Presenter: Abhay Asthana1, M.M. College of Pharmacy, M.M. University, Mulana-Ambala, Haryana, 133207, India. Authors: Abhay Asthana1, Gyati Shilakari Asthana1. VIEW ABSTRACT

477  Physicochemical evaluation of tadalafil solid dispersions obtained by antisolvent precipitation. Presenter: W Sawicki, Department of Physical Chemistry, Faculty of Pharmacy, Medical University of Gdansk, Poland. Authors: W Sawicki, K Wlodarski, Z Wojnarowska, M Paluch. VIEW ABSTRACT

478  Poly(carboxyalkyl methacrylamides) as Carriers for Controlled Drug Release. Presenter: H A Magaña-Badilla, Universidad Autónoma de Baja California, Mexico. Authors: H A Magaña-Badilla, A Serrano-Medina, I Cordova-Guerrero, J M Cornejo-Bravo. VIEW ABSTRACT

480  Preliminary In Vivo Evaluation of an Oral Multiple-Unit Formulation for Colonic Delivery of Insulin. Presenter: G Loreti, Università degli Studi di Milano, Italy. Authors: A Maroni, S Salmaso, M D Del Curto, G Loreti, P Caliceti, A Gazzaniga. VIEW ABSTRACT

481  Preparation of Proniosomes Containing Candesartan Cilexetil and Assessment of Their In Vivo Bioavailabilties. Presenter: N Yuksel, Ankara Univ, Turkey. Authors: N Yuksel, E Aksakal, Z S Bayindir, A T Ozcelikay. VIEW ABSTRACT

482  QbD-based Systematic Development of Self-Nanoemulsifying Systems for Improved Oral Bioavailability of Olmesartan. Presenter: S Beg, UIPS, Panjab University, India. Authors: S Beg, O Katare, G Sharma, B Garg, B Singh. VIEW ABSTRACT

483  Release adjustment of a drug combination formulated in erodible hydrophilic matrix tablets. Presenter: R Bodmeier, Freie Universität Berlin, Germany. Authors: A Y Chaerunisaa, A Dashevsky, R Bodmeier. VIEW ABSTRACT

484  Solid Crystalline Dispersions of Sildenafil Citrate in Ethyl Cellulose Produced by Hot-Melt Extrusion. Presenter: H Patil, Univ of Mississippi, U.S.A.. Authors: M A Repka, J T Morott, H Patil. VIEW ABSTRACT

485  Solid Dispersions Obtained Using Fusion Method Increases Solubility of Praziquantel. Presenter: P Dametto, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Brazil. Authors: P Dametto, C Ribeiro, O Freitas. VIEW ABSTRACT

486  Streamlining the Design of Sustained Release Matrix Tablets Using Mathematical Modeling For Drug Release Optimization. Presenter: Y Rosiaux, Gattefossé, France. Authors: Y Rosiaux, F Desvignes, J Girard, C Miolane, S Hughes, D Marchaud. VIEW ABSTRACT

487  Synthesis and Characterization of Vitamin B12 conjugates of Carboxymethyl CHT and TMC to make Nanoparticles for Oral Insulin Delivery. Presenter: N Jafary Omid, Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran, Iran. Authors: N Jafary Omid, S Maleki, F Dorkoosh. VIEW ABSTRACT

488  Tailoring Drug Release and Utilization of Process Analytical Techniques by FT-IR Imaging employing HME Systems. Presenter: J Park, Department of Pharmaceutics, School of Pharmacy, The University of Mississippi, U.S.A.. Authors: M A Repka, J Park, X Ye, P P Thipsay, J T Morott. VIEW ABSTRACT

489  The Accordion Pill™, a gastro-retentive controlled release system– a new solution for key unmet needs. Presenter: N Navon, VP R&D and Opertions, Intec Pharma, Israel. Authors: N Navon. VIEW ABSTRACT

490  The Effect of the Process on Drug Release of Compritol®888 Sustained Release Tablets: Direct Compression, Wet Granulation and Hot Melt Extrusion. Presenter: Y Rosiaux, Gattefossé, France. Authors: Y Rosiaux, F Desvignes, J Girard, C Miolane, S Hughes, D Marchaud. VIEW ABSTRACT

491  Trilaurin Diminishes Food Effect on the Release of Desmopressin from Solid Lipid Microparticles. Presenter: H Mu, University of Copenhagen, Denmark. Authors: P C Christophersen, D Vaghela, A Müllertz, M Yang, H M Nielsen, H Mu. VIEW ABSTRACT

492  Using novel nano-lipospheres to target M-cells for oral vaccine delivery. Presenter: L Wang, Institute of Process Engineering, Chinese Academy of Sciences, China. Authors: L Wang. VIEW ABSTRACT

Intracellular Delivery of Nucleic Acids and Proteins     [RETURN TO TOP]

493  Amphiphilic polysaccharide nanoballs with chaperon-like function for protein delivery. Presenter: S Takeda, Kyoto University, Japan. Authors: S Takeda, H Takahashi, S Sawada, Y Sasaki, K Akiyoshi. VIEW ABSTRACT

494  Delivery of Antioxidant Tat-Metallothionein Fusion Protein for Protection of Xenotransplanted Pancreatic Islets from Radical species  . Presenter: M Kim, Hanyang University, Korea. Authors: M Kim, D Lee, Y Kim. VIEW ABSTRACT

495  Efficient Cytosolic Release of Encapsulated Molecules in Exosomes Using pH-sensitive Fusogenic Peptide. Presenter: I Nakase, Osaka Prefecture University, Japan. Authors: I Nakase. VIEW ABSTRACT

496  Intracellular delivery and activation of the genetically encoded photosensitizer Killer Red by quantum dots encapsulated in polymeric micelles. Presenter: I Park, Chonnam National University, Korea. Authors: M Muthiah, W Kim, Y Lee, M Jang, I Park. VIEW ABSTRACT

497  Intracellular Delivery of Monoclonal Antibodies into the Living Cells by Charge-Conversional Polyion Complex Micelles  . Presenter: A Kim, Graduate School of Engineering, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8656, Japan, Korea. Authors: A Kim, Y Miura, T Ishii, N Nishiyama, K Kataoka. VIEW ABSTRACT

498  Lipid-nanoparticles for intracellular delivery of anti-microRNA oligonucleotides into non-small cell lung cancer cells. Presenter: M ISLAM, South Dakota State University, U.S.A.. Authors: M ISLAM, H Zhang. VIEW ABSTRACT

499  Mitochondria-targeted PLGA particles that protect against myocardial cell death. Presenter: A Wongrakpanich, College of Pharmacy, University of Iowa, U.S.A.. Authors: A Wongrakpanich, M Joiner, M E Anderson, A K Salem. VIEW ABSTRACT

500  Non-Toxic Endogenous nucleotides for Endosomal Disruption and Enhanced Gene Transfection. Presenter: H Cho, The Catholic University of Korea, South Korea. Authors: H Cho, Y Bae, H Kang. VIEW ABSTRACT

501  Non-Viral Delivery of Gene HPV-16 E7 into Mammalian Cells. Presenter: F Dorkoosh, Tehran Univ, Iran. Authors: M Dinarvand, A Tahamtan, F Atyabi, A Ghaemi, F Dorkoosh. VIEW ABSTRACT

502  Novel pH responsive polymeric vesicles for siRNA delivery to the tumor. Presenter: S Salmaso, Department of Pharmaceutical and Pharmacological Sciences, University of Padova - Italy, Italy. Authors: S Salmaso, E Gallon, F Mastrotto, S Bersani, J Sanchis, M J Vicent, G Mantovani, T Matini, C Alexander, P Caliceti. VIEW ABSTRACT

503  Polymer-mediated gene transfection efficiency is positively correlated with polyplex-induced autophagy in fibroblasts. Presenter: X Zhong, University of Minnesota, U.S.A.. Authors: X Zhong, C Wang. VIEW ABSTRACT

504  Polymersomes formed by phase-guided assembly as carriers for intracellular delivery of anti-tumor therapeutic proteins. Presenter: W Yuan, School of Pharmacy, Shanghai Jiao Tong University, China. Authors: W Yuan, D Xu, T Jin. VIEW ABSTRACT

505  The Influence of Dendritic Cell Type and Maturation State on Transfection Efficiency of Synthetic Polymer-based DNA Vaccine Carriers. Presenter: C Wang, University of Minnesota, U.S.A.. Authors: D Panus, W Ji, C Wang. VIEW ABSTRACT

Nanoparticle-Based Delivery to the Brain     [RETURN TO TOP]

507  Blood Brain Barrier Permeable Polymanntiol Gene Transporter Modified with Rabies Virus Glycoprotein with Selective Caveolar Transcytosis Pathway. Presenter: C Cho, Research institute for agriculture and life science, Seoul National University, South Korea. Authors: C Cho. VIEW ABSTRACT

508  Development and assesment of efavirenz-loaded SLN® for potential delivery to the CNS. Presenter: R B Walker, Rhodes University, South Africa. Authors: R B Walker, P Makoni, K Wa Kasongo. VIEW ABSTRACT

509  Development of cRGDfV-loaded chitosan nanoparticles using factorial design and evaluation of their in vitro cytotoxicity on glioblastoma cell line. Presenter: C P Kiill, UNESP, Brazil. Authors: C P Kiill, H S Barud, L Miziara, F Figueiró, A R Souza, A O Battastini, M D Gremião. VIEW ABSTRACT

510  Intranasally Administered Lectin Functionalized PEG-PLGA Nanoparticles: A Novel Drug Delivery System for the Treatment of Schizophrenia. Presenter: T Hoare, McMaster University, Canada. Authors: J Piazza, T Hoare, R K Mishra. VIEW ABSTRACT

511  Molecular design and biological evaluation of brain-targeting protein cage. Presenter: N Hamano, Center for Advanced Medical Innovation, Kyushu University, Japan. Authors: N Hamano, M Murata, T Kawano, S Narahara, J Piao, K Ohuchda, M Hashizume. VIEW ABSTRACT

514  Polymersomes Conjugated with Des-octanoyl ghrelin for the Delivery of Therapeutic Agents into Brain Tissues. Presenter: Y Chen, National Taiwan University, Taiwan. Authors: Y Chen, C Chiang, L Chen, Liao, Hsieh, W Lin. VIEW ABSTRACT

515  Protein Adsorption Patterns from Differently Coated Azithromycin i.v. Nanocrystals. Presenter: S Staufenbiel, Institute of Pharmaceutics, Biopharmaceutics and NutriCosmetics, FU Berlin, Berlin, 12169, Germany, Germany. Authors: S Staufenbiel, N Jin, R H Müller. VIEW ABSTRACT

516  Self-assembling nanoparticles containing zoledronic acid: A new scenario for the treatment of glioblastoma. Presenter: G Salzano, Department of Pharmacy, Università degli Studi di Napoli Federico II, Via Montesano, 49, 80131 Naples, Italy., Italy. Authors: G Salzano, G De Rosa. VIEW ABSTRACT

519  Transferrin-bearing Polypropylenimine Dendrimer for Targeted Gene Delivery to the Brain. Presenter: S Somani, University of Strathclyde, United Kingdom. Authors: S Somani, D Blatchford, G Robb, O Millington, C Dufes. VIEW ABSTRACT

744  Anti-Parkinson Drug Delivery to Brain by Targeting Blood-Brain Barrier. Presenter: D Keskin, Middle East Technical University, Turkey. Authors: Z Barcin, A Tezcaner, S Korkmaz, D Keskin. VIEW ABSTRACT

Nanoparticles in Tumor Treatment     [RETURN TO TOP]

520  3D Cancer Cell Spheroids as a Model For Investigating Co-Delivery of Paclitaxel and Curcumin by Targeted Mixed Micelles. Presenter: C Sarisozen, Northeastern University, U.S.A.. Authors: C Sarisozen, A H Abouzeid, N R Patel, F Perche, V P Torchilin. VIEW ABSTRACT

522  A molecular pulling/pushing nanovehicle. Presenter: J LEE, The Catholic University of Korea, South Korea. Authors: J LEE. VIEW ABSTRACT

523  A Multi-Scale Hybrid Nanoparticle for Controlled Release Kinetics and Efficient Intratumoral Penetration. Presenter: J Bugno, Department of Biopharmaceutical Sciences, University of Illinois at Chicago, U.S.A.. Authors: J Bugno, S Sunoqrot, S Hong. VIEW ABSTRACT

524  A novel Nanostructure Lipid Carriers with Charge-reversal and pH-Sensitive Membranolytic Capability for Lysosomolytic Anti-cancer Drug Delivery. Presenter: M Sun, China Pharmaceutical University, China. Authors: M Sun, Q Zhao, Y Xie, H Qiao, Z Su, Q Ping. VIEW ABSTRACT

525  A Pharmacokinetic Modeling Approach for Personalization of Nanomedicine. Presenter: A R Kirtane, University of Minnesota, U.S.A.. Authors: A R Kirtane, R A Siegel, J Panyam. VIEW ABSTRACT

526  A Synergistic Theranostic Approach Using a Targeted siRNA Drug Delivery Platform and a Phthalocyanine-Loaded Dendrimer for Ovarian Cancer Treatment. Presenter: o taratula, oregon state university, U.S.A.. Authors: C Schumann, o taratula, a palmer, l cronk, m naleway, b dolan, o taratula. VIEW ABSTRACT

529  Acid-activatable fullerene nanogel. Presenter: S KIM, catholic university of KOREA, South Korea. Authors: S KIM, D LEE. VIEW ABSTRACT

531  Angiopep-2-conjugated Liposomes Encapsulating Dibenzazepine for Glioblastoma Multiforme. Presenter: S Xuan, Sookmyung Women’s University, South Korea. Authors: S Xuan, S Lee. VIEW ABSTRACT

532  Anti-angiogenic effect of heparin-taurocholate conjugate on mouse glioblastoma animal model. Presenter: J Seol, Department of Bioengineering, College of Engineering, Hanyang University, Republic of Korea, Korea. Authors: J Seol, D Lee, Y Byun. VIEW ABSTRACT

533  Anti-Tumor Effect of Heparin-Taurocholate Conjugate to Various Kinds of Orthotopic Pancreatic Cancer Animal Model. Presenter: H Jeong, Hanyang University, Seoul, Korea, Korea. Authors: H Jeong, Y Byun, D Lee. VIEW ABSTRACT

534  Bacterially Derived Outer Membrane Vesicles as Cancer Cell-Specific Drug Delivery Vehicles. Presenter: V Gujrati, KAIST, Korea. Authors: V Gujrati, S Kim, S Kim, S Jon. VIEW ABSTRACT

535  Biofunctionalized Magnetic Nanoparticle for Targeted Drug Delivery and Thermal Therapy. Presenter: j gupta, Indian Institute Of Technology Bombay, India. Authors: j gupta, p bhargava, d bahadur. VIEW ABSTRACT

536  Bioreducible poly(ethylene glycol)-pheophorbide a conjugate for the preparation of self-quenchable nanoparticles with controllable photoactivity. Presenter:H Cho. The Catholic University of Korea, Korea. VIEW ABSTRACT

537  Cathepsin B degradable peptidic macromolecules as delivery vehicle for Geldanamycin. Presenter: J Suárez del Pino, University of Illinois at Chicago, Spain. Authors: J Suárez del Pino, R Kolhatkar, V Kolhatkar. VIEW ABSTRACT

538  Characterization of optimally designed liposomal formulation of Oxaliplatin. Presenter: Y Doi, Taiho Pharmaceuticals Co., Ltd., Japan. Authors: Y Doi, T Ishida, H Kiwada. VIEW ABSTRACT

539  Chitosan-g-polycaprolactone Graft Copolymer Nanoparticles for Paclitaxel and p53 Plasmid DNA Delivery. Presenter: P Davoodi, National University of Singapore, Singapore. Authors: P Davoodi, Z Chia, C Wang, M Srinivasan. VIEW ABSTRACT

540  Cholesterol Esterification-Blocking Nanoparticles for Targeted Aggressive Cancer Therapy. Presenter: S Lee, Biomedical Engineering, Purdue University, U.S.A.. Authors: S Lee, J Li, J Nee, K Park, J Cheng. VIEW ABSTRACT

542  Delivery of siRNA for breast cancer. Presenter: M Gujrati, Department of Biomedical Engineering, Case Western Reserve University, U.S.A.. Authors: M Gujrati, J G Parvani, M Mack, W P Schiemann, Z Lu. VIEW ABSTRACT

543  Densely PEG Coated Cisplatin Nanoparticles for Treatment of Malignant Glioma. Presenter: C A Zhang, Johns Hopkins University School of Medicine, U.S.A.. Authors: C A Zhang, E Nance, P Mastorakos, J Chisholm, S Berry, J Hanes. VIEW ABSTRACT

544  Developement of a therapeutic cancer vaccine based on polymeric nanoparticles containing HPV synthetic long peptide and poly IC. Presenter: S Rahimian, Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Netherlands. Authors: S Rahimian, M F Fransen, J Kleinovink, J Christensen, M Amidi, F Ossendorp, W E Hennink. VIEW ABSTRACT

545  Development of a specific targeting system for pancreatic tumors utilizing antibody conjugated Pt-loaded micelles. Presenter: J Ahn, The University of Tokyo, Japan. Authors: J Ahn, Y Miura, N Yamada, A Kim, T Chida, H Cabral, Y Matsumura, N Nishiyama, K Kataoka. VIEW ABSTRACT

546  Development of an Externally Activated Drug Delivery Vehicle. Presenter: L A Moir, University of Nottingham, United Kingdom. Authors: L A Moir, S G Spain, M Ashford, P Gellert, J Aylott, C Alexander. VIEW ABSTRACT

547  Development of glutathione-sensitive polymeric micelles for the delivery of camptothecin to solid tumors. Presenter: H Yen, Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, Taiwan. Authors: H Yen, H Cabral, H Koori, Y Miura, P Mi, A Kim, K Miyazaki, N Nobuhiro, K Kataoka. VIEW ABSTRACT

548  Development of Localized Cisplatin Chemotherapy: From Benchside to Investigational New Drug Application. Presenter: S Cai, HylaPharm, U.S.A.. Authors: S Cai, D Vartia, J N Bryan, D J Aires, M Forrest. VIEW ABSTRACT

549  Development of Nanobody Targeted Liposomes Directed Against Tumors for Image-Guided Drug Delivery. . Presenter: M Bolkestein, Erasmuc Medical Center, Netherlands. Authors: M Bolkestein, D Drabek, T L ten Hagen, M de Jong, F G Grosveld, G A Koning. VIEW ABSTRACT

551  Development of stomach cancer-targeted and cytotoxic hybrid peptides. Presenter: B Lee, Kyungpook National University (KNU), South Korea. Authors: B Lee. VIEW ABSTRACT

553  Disulfide nanosponges as innovative glutathione-responsive nanocarrier for doxorubicin delivery. Presenter: R Cavalli, Dipartimento di Scienza e Tecnologia del Farmaco, Università di Torino, Italy. Authors: R Cavalli, M Argenziano, C Dianzani, G Zara, F Caldera, F Trotta. VIEW ABSTRACT

554  Encapsulation in nanoparticles improves anti-cancer efficacy of carboplatin. Presenter: T Sadhukha, University of Minnesota, U.S.A.. Authors: T Sadhukha, S Prabha. VIEW ABSTRACT

556  Enhanced Cancer Cell Cytotoxicity of Dual Ligand-Targeted Doxorubicin-Loaded Liposomes. Presenter: S Sriraman, Graduate student, U.S.A.. Authors: S Sriraman, V P Torchilin. VIEW ABSTRACT

557  Enhanced Paclitaxel Loading Capacity of Micelles by Introducing Fmoc as a Drug-Interactive Motif. Presenter: Y Zhang, University of Pittsburgh, U.S.A.. Authors: Y Zhang, Y Huang, W Zhao, J Lu, P Zhang, X Zhang, J Li, R Venkataramanan, S Li. VIEW ABSTRACT

558  Enhancement of anti-tumor activity of hybrid peptide by conjugation with thiolated carboxymethyl dextran via disulfide linkers. Presenter: A Gaowa, Graduate School of Medicine and Public Health, Kyoto University, Japan. Authors: A Gaowa, T Horibe, M Kohno, H Harada, M Hiraoka, Y Tabata, K Kawakami. VIEW ABSTRACT

559  Facile preparation of paclitaxel-loaded self-assembled polyethyleneglycol-albumin conjugate nanoparticles for effective cancer therapy. Presenter: M Kim, Sungkyunkwan University, South Korea. Authors: M Kim, Y Jang, M Lee, J Lee, I Kwon, S Kim, J Jeong. VIEW ABSTRACT

560  Formulation of Stabilized Ultrasound Visible Nanoparticles for Thermal Sensitizer Delivery . Presenter: P H Perera, Case Western Reserve University, U.S.A.. Authors: P H Perera, H Wu, P Kota, A A Exner. VIEW ABSTRACT

561  Gold Nanorods and Paclitaxel Loaded Solid Lipid Nanoparticles and Their Therapeutic Potential for Near-Infrared Photothermal-Chemotherapy of Cancer. Presenter: J Kim, Samsung Biomedical Research Institute, South Korea. Authors: J Kim, Y Kim, T Park, J Lee, K Park. VIEW ABSTRACT

564  Hyaluronic Acid Derived Fluorescent Nanoparticles for Image-Guided Tumor Surgery. Presenter: A M Mohs, Wake Forest University Health Sciences, U.S.A.. Authors: A M Mohs, T K Hill, S Kelkar, F C Marini, E A Levine. VIEW ABSTRACT

565  Hydrophobically-modified hyaluronic acid nanocapsules for targeted docetaxel delivery. Presenter: A Cadete Pires, CIMUS - University of Santiago de Compostela, Spain. Authors: A Cadete Pires, L Gonçalves, M Garcia-Fuentes, D Torres, M Besev, P Dhal, M J Alonso. VIEW ABSTRACT

566  Improved Safety and Efficacy of Surface Engineered Docetaxel Nanoparticles for Targeting in Prostate Cancer. Presenter: D K Singh, 3School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston, PR1 2HE,, United Kingdom. Authors: N P Saini, D K Singh. VIEW ABSTRACT

568  In Vivo Anti-Tumor Efficacy Study of a Novel Wnt pathway Inhibitor Packed in RH40 Micelles. Presenter: C Li, Pharmacy School of Shanghai Jiaotong University, China. Authors: C Li, X Chen, Y Xu. VIEW ABSTRACT

569  Investigating the relationship between interstitial fluid pressure, perfusion, and liposome accumulation in solid tumors.. Presenter: S Stapleton, Unversity of Toronto, Canada. Authors: S Stapleton, C Allen, D A Jaffray. VIEW ABSTRACT

571  Magnetic and radiolabeled biodegradable nanoparticles for dual medical imaging. Presenter: I Rosenberger, Institute of Pharmaceutical Technology, Germany. Authors: I Rosenberger. VIEW ABSTRACT

573  Monitoring Nanoemulsion-Based Oxygen Delivery using Non-Invasive Tumor Hypoxia Imaging. Presenter: D Song, University of Connecticut, U.S.A.. Authors: D Song, T Tran, D Hargrove, Q Zhu, M Smith, X Lu. VIEW ABSTRACT

574  MUC 1 aptamer conjugated to chitosan nanoparticles, an efficient targeted carrier designed for SN38 delivery toward colon cancer  . Presenter: S Hadipour Moghaddam,, U.S.A.. Authors: E sayari, F Atyabi, M Amini, S Hadipour Moghaddam. VIEW ABSTRACT

575  Multiscale Drug Delivery System: Micelles Encapsulated in Hydrogels. Presenter: M Tang, University of Illinois at Chicago, U.S.A.. Authors: M Tang, L Nwanah, Y Zhang, R A Gemeinhart. VIEW ABSTRACT

576  Nanobioconjugates for Triple-Negative Breast Cancer Treatment. Presenter: J PORTILLA-ARIAS, Nanomedicine Research Center, Department of Neurosurgery, Cedars-Sinai Medical Center, U.S.A.. Authors: J PORTILLA-ARIAS. VIEW ABSTRACT

578  Nanoparticle Depot for Intraperitoneal Chemotherapy of Ovarian Cancer . Presenter: B SUN, Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, U.S.A.. Authors: B SUN, Y YEO. VIEW ABSTRACT

579  Nanostructured Lipid Carrier Co-loaded with Doxorubicin and Docosahexaenoic Acid: a Novel Strategy to Improve Activity and Overcome Tumor Resistance. Presenter: S V Mussi, Northeastern University, U.S.A.. Authors: S V Mussi, R Sawant, F Perche, R B Azevedo, M C Oliveira, L A Ferreira, V P Torchilin. VIEW ABSTRACT

580  Novel Mg-Al Layered Double Hydroxide-Fe3O4 Magnetic Nanohybrids for Efficient Thermo-Chemo Therapy of Cervical Cancer. Presenter: E V Prasadarao K, Indian Institute of Technology Bombay, India. Authors: E V Prasadarao K, S Nigam, M Aslam, D Bahadur. VIEW ABSTRACT

582  Novel Self-Associating Poly(ethylene oxide)-b-poly(e-caprolactone) based Drug Conjugate for Delivery of STAT3 Inhibitor JSI-124 to Murine B16 Melanoma. Presenter: S M Garg, University of Alberta, Canada. Authors: S M Garg, M R Vakili, A Lavasanifar. VIEW ABSTRACT

583  Optimization of thermosensitive liposome formulations for intravascular drug release. Presenter: W Lokerse, Erasmus MC, Netherlands. Authors: W Lokerse. VIEW ABSTRACT

584  Oxidative stress amplifying polymeric micelles as novel anticancer therapeutics. Presenter: D Lee, Chonbuk National University, Korea. Authors: D Lee, E Han, W Cho, B Kwon. VIEW ABSTRACT

585  PEG-Farnesylthiosalicylate Conjugate with a Drug Interactive Motif as an Improved Micellar System for Delivery of Anticancer Agents. Presenter: X Zhang, University of Pittsburgh, U.S.A.. Authors: X Zhang, Y Huang, W Zhao, J Lu, P Zhang, Y zhang, J Li, X Gao, R Venkataramanan, S Li. VIEW ABSTRACT

586  PEG-Peptide Conjugate Equipped with Drug-Interactive Motifs as a Safe and Effective Delivery System for Paclitaxel. Presenter: P Zhang, University of Pittsburgh, U.S.A.. Authors: P Zhang, Y Huang, H Liu, R Marquez, J Lu, W Zhao, X Zhang, J Li, R Venkataramanan, L Xu, X Gao, S Li. VIEW ABSTRACT

587  pH responsive liposomes for gemcitabine enhanced delivery to cancer cells. Presenter: S Salmaso, Department of Pharmaceutical and Pharmacological Sciences, University of Padova - Italy, Italy. Authors: S Salmaso, S Bersani, E Ambrosio, E Gallon, C Brazzale, P Caliceti. VIEW ABSTRACT

588  Phage display based competitive cell panning identifies candidate scFv with selective affinity to pre-metastatic, EMT transitioned breast cancer cells. Presenter: S Kalscheuer, University of Minnesota, U.S.A.. Authors: S Kalscheuer. VIEW ABSTRACT

589  Polyethylene Glycol Conjugated Polymeric Nanocapsules for Targeted Delivery of Quercetin to Folate-Expressing Cancer Cells In Vitro and In Vivo. Presenter: K T Al-Jamal, King's College London, United Kingdom. Authors: K T Al-Jamal. VIEW ABSTRACT

590  Polymer-bound NIRF Probe to Improve Colorectal Cancer Detection. Presenter: A David, Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Israel. Authors: A David, I Kogan-Zviagin, M Golan. VIEW ABSTRACT

591  Polymeric micelles based on vitamin E-contained comb-type polymer for application in cancer therapy. Presenter: K Lee, National Yang-Ming University, Taiwan. Authors: K Lee, Lo. VIEW ABSTRACT

592  Polymeric micelles containing anti-survivin siRNA and Paclitaxel in combination: A promising strategy to reverse the drug resistance in ovarian cancer. Presenter: G Salzano, Center for Pharmaceutical Biotechnology and Nanomedicine, Northeastern University, Boston, Massachusetts, United States., Italy. Authors: G Salzano, G Navarro, M Trivedi, V Torchilin. VIEW ABSTRACT

594  Preparation of PLGA nanoparticles to enhance intracellular uptake in dendritic cell. Presenter: Y Byeon, Department of Immunology, School of Medicine, Konkuk University, Chungcheongbukdo 380-701, South Korea, South Korea. Authors: Y Byeon, H HAN. VIEW ABSTRACT

596  Preparation, Characterization and Evaluation of a Liposomal Formulation for Co-Delivery of Paclitaxel and Lapatinib. Presenter: F Dorkoosh, Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of medical sciences, Iran. Authors: F Ravar, E Saadat, P Dehghan, F Dorkoosh. VIEW ABSTRACT

597  Radiosensitization Effect of Gossypol-loaded Pluronic Micelles. Presenter: K Tomoda, School of Pharmacy, University of Wisconsin-Madison, U.S.A.. Authors: K Tomoda, C Chiang, K R Kozak, G S Kwon. VIEW ABSTRACT

598  Redox-Responsive Core Cross-linked Hyaluronic Acid Nanoparticles for Intracellular Delivery of Doxorubicin. Presenter: H Ko, Sungkyunkwan University, South Korea. Authors: H Ko, H Han, G Saravanakumar, H Yoon, J Jeon, J Park. VIEW ABSTRACT

600  Remote Loading of a Novel Acidic Hypoxia-Activated Prodrug into Liposomes with High Entrapment Efficiency and Drug Loading. Presenter: M M Yang, School of Pharmacy, University of Auckland, New Zealand. Authors: M M Yang, Z Wu, W Wilson, B Palmer. VIEW ABSTRACT

602  Reversal of Chemoresistance in Ovarian Cancer Cells By Liposomal Co-delivery of Tariquidar and Paclitaxel. Presenter: S Sriraman, Graduate student, U.S.A.. Authors: S Sriraman, V P Torchilin. VIEW ABSTRACT

603  siRNA Nanoparticles Targeted to the Extra Cellular Matrix for Cancer Therapy. Presenter: M Naim, Institute for Drug Research, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, 91120, Israel, Israel. Authors: M Naim, M M Nordling-David, Z Granot, A Morss-Clyne, A Dagan, G Golomb. VIEW ABSTRACT

604  Smart ZnO-embedded pH-responsive Liposomes for Cancer Therapy: Triggering Mechanism and Drug Release Behavior. Presenter: N Tripathy, Dept. of BIN Fusion Tech, Korea. Authors: N Tripathy, R Ahmad, K Aa, G Khang, Y Hahn. VIEW ABSTRACT

605  SPIO-Doxorubicin Conjugates as a Tumor Theranostic Agent Enhanced by Applying Magnetic Fields. Presenter: Y chen, National Taiwan University, Taiwan. Authors: Y chen, P Liang, Chiang, Y Lin, W Hsieh, M Lin, W Lin. VIEW ABSTRACT

606  Star Polymers with Tailored Transition Temperature for Optimal 5-Fluoruracil Drug Delivery. Presenter: E Sanchez-Bustos, Universidad Autonoma de Baja California, Mexico. Authors: E Sanchez-Bustos, J M CORNEJO-BRAVO, A LICEA-CLAVERIE. VIEW ABSTRACT

607  Surface Chemistry Modification of Paclitaxel Nanocrystals and In Vitro Evaluation. Presenter: Y Chen, Purdue University, U.S.A.. Authors: Y Chen, T Li. VIEW ABSTRACT

608  Synergistic Delivery of Curcumin to Tumors via PEG-derivatized FTS-based Micellar System. Presenter: Y Chen, University of Pittsburgh, U.S.A.. Authors: Y Chen, X Zhang, J Lu, Y Huang, J Li, S Li. VIEW ABSTRACT

609  Synthesis, Evaluation and Optimization of Novel Polymeric Micelle Based on Hyaluronic Acid and Phospholipids for Targeted Delivery of Paclitaxel. Presenter: F Dorkoosh, Tehran Univeersity of Medical Sciences, Iran. Authors: E Saadat, F Dorkoosh. VIEW ABSTRACT

610  Synthetic high density lipoproteins for targeted delivery of withalongolides to adrenocortical carcinomas . Presenter: R Kuai, University of Michigan, U.S.A.. Authors: R Kuai, C Subramanian, B N Timmermann, J J Moon, M S Cohen, A Schwendeman. VIEW ABSTRACT

614  Targeting Multifunctional Nanomedicine Delivery System for Pancreatic Cancer. Presenter: J Sun, Jinling Hospital, Clinical School of Medical College, Nanjing University; Department of Radiology, Northwestern University, Feinberg School of Medicine, China. Authors: J Sun, D Kim, A C Larson, G Lu. VIEW ABSTRACT

615  The Preparation of High-content Gemcitabine pH Sensitive Liposomes and Evaluation of their Cytotoxicity to Drug Resistant Pancreatic Cancer Cells. Presenter: H Xu, The University of Auckland, New Zealand. Authors: H Xu, J Paxton, Y Li, Z Wu. VIEW ABSTRACT

617  Titanium oxide-based nanoparticles for sonodynamic threapy of cancer. Presenter: D You, Sungkyunkwan university, South Korea. Authors: D You, V Deepagan, S Jeon, I Kwon, K Kim, J Park. VIEW ABSTRACT

618  Trilayer Micelles for Combination Delivery of Rapamycin and siRNA . Presenter: S Zeng, UW-Madison, U.S.A.. Authors: S Zeng. VIEW ABSTRACT

619  Tumor Accumulation and Penetration of Mesoporous Silica Nanoparticles and the Potential Role of Peritoneal Macrophages . Presenter: L A González-Fajardo, University of Connecticut, U.S.A.. Authors: L A González-Fajardo, T Tran, D Hargrove, M Brewer, X Lu. VIEW ABSTRACT

621  Tumor Regression following Intravenous Administration of Lactoferrin- and Lactoferricin-bearing Dendriplexes. Presenter: C Dufes, University of Strathclyde, United Kingdom. Authors: C Dufes, L Lim, P Koh, S Somani, M Al Robaian, R Karim, Y Yean, J Mitchell, R J Tate, R Edrada-Ebel, D R Blatchford, M Mullin. VIEW ABSTRACT

622  Tumor-targeted Delivery of Bevacizumab Using Heparin-Pluronic Nanogels . Presenter: J Bae, Ajou University, South Korea. Authors: J Choi, J Bae, S Son, K Kim, K Park. VIEW ABSTRACT

623  Tumor-targeted Delivery of Paclitaxel using Low Density Lipoprotein-mimetic Solid Lipid Nanoparticles. Presenter: J Kim, Samsung Biomedical Research Institue, South Korea. Authors: J Kim, Y Kim, K Bae, T Park, J Lee, K Park. VIEW ABSTRACT

625  Variation of PEG Length and Its Effect on the Targeting Efficacy of APTEDB-Liposome in vitro and in vivo. Presenter: P Saw, Korea Advanced Institute of Science and Technology, Korea. Authors: P Saw, J Park, E Lee. VIEW ABSTRACT

Novel Developments in Formulation, Analytical Chemistry, and Processing in Animal Health and Preclinical Sciences     [RETURN TO TOP]

627  Continuous production of Solid Lipid Nanoparticles via Hot-Melt Extrusion. Presenter: H Patil, University of Mississippi, U.S.A.. Authors: H Patil, M Repka, S Majumdar, X Feng. VIEW ABSTRACT

628  Detection of Cathepsin-K activity for osteoarthritic diagnosis using FRET with a gold nanorod-based fluorescent probe. Presenter: C Lee, Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Taiwan. Authors: C Lee, J Lin, H Chiu, C Wang. VIEW ABSTRACT

630  Development and Validation of an Analytical Method for Ketoprofen Determination in Matrix Tablets by High Performance Liquid Chromatography. Presenter: M L Vueba, Instituto Superior de Ciências da Saúde da Universidade Agostinho Neto, Angola. Authors: M L Vueba. VIEW ABSTRACT

632  Development of manufacturing process for a parenteral depot formulation by in situ precipitation. Presenter: E Corona, Patheon Italia S.p.A., Italy. Authors: E Corona. VIEW ABSTRACT

634  In situ forming composite gel (ISFcG) designed for local antibiotic delivery and bone regeneration. Presenter: B Conti, Department of Drug Sciences, University of Pavia, Italy. Authors: B Conti, R Dorati, I Genta. VIEW ABSTRACT

636  Rapid HPLC Method supporting rennin inhibitor enteric coated beads formulation development. Presenter: S Kirsh, Patheon Pharmaceutical, U.S.A.. Authors: S Kirsh. VIEW ABSTRACT

638  Role of water sorption capacity of tableting excipients to protect protein drugs from structural changes during storage using infrared spectroscopy. Presenter: M Klukkert, University of Hamburg, Germany. Authors: M Klukkert, M Doreth, H Grohganz, T Rades, C S Leopold. VIEW ABSTRACT

639  Surface engineered Nanoannomaal: A nanoparticulate system for targeted antimalarial chemotherapy. Presenter: K K Singh, UCLAN, United Kingdom. Authors: S S Sawant, K K Singh. VIEW ABSTRACT

640  Targeted Nanoparticle for Cancer Imaging. Presenter: R Savla, Rutgers University, U.S.A.. Authors: R Savla, O Garbuzenko, L Rodriguez-Rodriguez, T Minko. VIEW ABSTRACT

641  Validation of an LC-MS/MS method for the simultaneous quantification of eight permeability standard drugs. Presenter: M Leclaire, Université de Montréal, Canada. Authors: M Leclaire, I Marcotte, G Leclair. VIEW ABSTRACT

Overcoming Barriers in the GI Tract     [RETURN TO TOP]

642  Amorphous Drugs in Porous Materials – Stability, Solubility & Tablet Performance. Presenter: R H Müller, Free University of Berlin, Germany. Authors: R H Müller, C M Keck, Q Wei. VIEW ABSTRACT

643  Cell penetrating peptides - is charge important for improved uptake of nanoparticles?. Presenter: A McDowell, School of Pharmacy, University of Otago, New Zealand. Authors: A McDowell, J Z Chiu, I G Tucker. VIEW ABSTRACT

644  Comparison of CapsMorph® and Nanocrystals of Poorly Soluble Drugs. Presenter: R H Müller, Free University of Berlin, Germany. Authors: Q Wei, R H Müller, C M Keck. VIEW ABSTRACT

645  pH-dependent FcRn-Mediated Transcytosis of Nanoparticles across the Intestinal Epithelium. Presenter: M Yu, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, China. Authors: M Yu. VIEW ABSTRACT

646  Predicting the Impact of Ingested Lipids on Orally Delivered Drug Absorption: Mechanistic Studies and Modeling . Presenter: S Di Maio, Northeastern University, U.S.A.. Authors: S Di Maio, D Budil, R Carrier. VIEW ABSTRACT

Overcoming Biological Barriers     [RETURN TO TOP]

648  Development and Antimicrobial Evaluation of Cefuroxime Axetil Loaded Chitosan Films for the Treatment of Periodontitis. Presenter: S Senel, Hacettepe University, Turkey. Authors: R Sheshala, X Chan, F Chong, K Dua, M Cansiz, M J Rathbone, S Senel. VIEW ABSTRACT

649  Development of a novel mucoadhesive precursor of based-chitosan liquid crystal system for buccal administration.. Presenter: G Calixto, State University of São Paulo, Brazil. Authors: G Calixto, F Victorelli, M Chorilli. VIEW ABSTRACT

650  Effect of low frequency sonophoresis in cetuximab skin penetration: a preliminary study. Presenter: R Petrilli, University of Sao Paulo, Brazil. Authors: R Petrilli, J O Eloy, R V Lopez. VIEW ABSTRACT

652  How terpene-based nanoparticles, harboring stimuli-responsive linker, overcome poor diffusion of ß-lactam antibiotic to treat intracellular infection?. Presenter: N Abed, Institut Galien - Paris Sud - UMR8612, France. Authors: N Abed. VIEW ABSTRACT

653  Human Serum Albumin Based Nanoparticles of Bridelia Retusa Extract as  Vaginal Microbicide. Presenter: K K Singh, School of Pharmacy and Biomedical Sciences, University of Cental Lancashire, Preston, United Kingdom. Authors: K K Singh, A P Palshetkar. VIEW ABSTRACT

654  In vivo Feasibility Study on Iontophoretic Transbuccal Peptide Drug Delivery in Rabbits. Presenter: J Seo, Keimyung Univ, Korea. Authors: J Seo, D Oh, S Lee. VIEW ABSTRACT

655  Nanoparticle Delivery to Intravaginal Mucosal Tissue and Target Lymphoid Organs Using Chitosan as a Mucosal Adjuvant. Presenter: J Park, Bioengineering at University of Washington, U.S.A.. Authors: J Park, R Ramanathan, L Pham, K Woodrow. VIEW ABSTRACT

656  Polyethylene glycol-Rhodamine 123 Conjugates Remain P-gp Substrates . Presenter: L A Crawford, Cornell University, U.S.A.. Authors: L A Crawford, D Putnam. VIEW ABSTRACT

657  Rapid Screening of Anti-cancer Drugs and Delivery Vehicles Using Tumor-microenvironment-on-chip. Presenter: A Ozcelikkale, School of Mechanical Engineering, Purdue University, West Lafayette, Indiana, U.S.A.. Authors: A Ozcelikkale, C S Shin, K Park, B Han. VIEW ABSTRACT

658  Release and corneal permeation of 2-oxothiazolidine-4-carboxylic acid from chitosan nanoparticles for cataract treatment. Presenter: A A Al-kinani, School of Pharmacy and Chemistry, Kingston University London, United Kingdom. Authors: A A Al-kinani, G Calabrese, A Vangala, B K Pierscionek, D P Naughton, R G Alany. VIEW ABSTRACT

659  Reverse engineering tumor invasiveness on nanoparticle surface to improve tumor penetration of nanoparticles. Presenter: A R Kirtane, University of Minnesota, U.S.A.. Authors: A R Kirtane, J Panyam. VIEW ABSTRACT

660  Rheological and bioadhesive behavior of hexagonal lyotropic based-chitosan liquid crystal systems intended to buccal drug delivery.. Presenter: G Calixto, State University of São Paulo, Brazil. Authors: G Calixto, F Victorelli, M Chorilli. VIEW ABSTRACT

661  Solubility and Cellular Internalization Enhancement of Formulations of Paclitaxel with ß-Cyclodextrins:  Physicochemical and In Vitro Assessments. Presenter: M Shah, Rutgers University, U.S.A.. Authors: M Shah, V Shah, T Minko. VIEW ABSTRACT

662  Stiffness of Injection Site Increases Penetration Distance of Drug Released from In Situ Forming Polymer Implants . Presenter: C Hernandez, Department Of Biomedical Engineering, Case Western Reserve University, U.S.A.. Authors: C Hernandez, P Kota, A A Exner. VIEW ABSTRACT

663  Targeted miRNA delivery for psoriasis treatment based on modified starch and ultrasound application. Presenter: R Lifshiz, Department of Chemical Engineering, Ben Gurion University of the Negev, Israel. Authors: R Lifshiz, G Lerman, R Goldbart, T Traitel, D Avni, Y Sidi, J Kost. VIEW ABSTRACT

664  Topical Nanomedicine – overcoming the barriers. Presenter: T W Prow, The University of Queensland, Australia. Authors: T W Prow. VIEW ABSTRACT

665  Two-photon microscopy analysis of drug delivery through the blood-brain barrier using focused ultrasound in a mouse model of Alzheimer's disease. . Presenter: A Burgess, Sunnybrook Research Institute, Canada. Authors: A Burgess, T Nhan, C Moffatt, K Hynynen. VIEW ABSTRACT

Proteins, Peptides, and Vaccines     [RETURN TO TOP]

666  A Designed Nanocage Displaying Ligand-specific Peptide Bunches for High Affinity and Biological Activity. Presenter: I Kim, Kyungpook National University, School of Medicine, Korea. Authors: S Kim, I So, I Kim. VIEW ABSTRACT

667  Adjusting bevacizumab – lipid particles eletrostatic interactions by freeze-drying process: towards new carriers for monoclonal antibodies. Presenter: C P Kiill, School of Pharmaceutical Sciences/UNESP, Brazil. Authors: L Miziara, C P Kiill, J D Alonso, M P Gremião. VIEW ABSTRACT

668  Basic analysis for screening a novel bone-regenerating peptide from the phage peptide library. Presenter: N Takashi, Graduate School of Pharmaceutical Sciences, Osaka University, Japan. Authors: N Takashi, M Yohei, S Yasutaka, K Genki, O Keiichi, A Kazuhiro, H Kazuma, Y Yasuo, N Kazuya, K Haruhiko, T Shin-ichi, T Yasuo. VIEW ABSTRACT

669  Biomimetically Engineered Demi-bacteria Potentiate Vaccination Against cancer. Presenter: W Wei, National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences. Beijing, China., China. Authors: W Wei, D Ni, H Yue, G Ma. VIEW ABSTRACT

671  Ceramic-based Nanosystem for Oral Delivery of Proteins and Peptides . Presenter: D Lowry, Aston University, United Kingdom. Authors: F A Abdulrazzaq, D Lowry, Y Perrie. VIEW ABSTRACT

672  Comparison of two different site-specific conjugates of hGH in biophysical and in vivo studies. Presenter: G Pasut, University of Padua, Italy. Authors: A Grigoletto, A Mero, G Pasut. VIEW ABSTRACT

673  Comprehensive characterization of vesicle formation with a self-assembling amphiphilic peptide. Presenter: M Rad-Malekshahi, Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, 3584 CG Utrecht, The Netherlands, Netherlands. Authors: M Rad-Malekshahi, W Hennink, E Mastrobattista. VIEW ABSTRACT

674  Conjugation free oral microparticulate meningitis vaccine formulation and evaluation. Presenter: R P Gala, Mercer University, U.S.A.. Authors: R P Gala, R V Ubale, S M Zughair, M J D'Souza. VIEW ABSTRACT

678  Delivering Recombinant Melittin for Treatment of High Grade Astrocytoma. Presenter: J S Buhrman, University of Illinois at Chicago, U.S.A.. Authors: J S Buhrman, J E Rayahin, R A Gemeinhart. VIEW ABSTRACT

680  Determining Ideal Excipient for Encapsulating Proteins inside PLGA Microspheres. Presenter: R A Trindade, Federal University of Rio de Janeiro, Brazil. Authors: R A Trindade, A Melo-Filho, L R Carvalho, M B dos Reis, P H Veloso-Junior. VIEW ABSTRACT

681  Development and anti-tumor activity of a novel anti-human claudin-3/-4 dual-specific antibody. Presenter: Y Kimura, Graduate School of Pharmaceutical Sciences, Osaka Universty, Japan. Authors: Y Kimura, X Li, M Iida, M Tada, A Ishii, M Fukasawa, Y Kawahigashi, A Watari, K Yagi, M Kondoh. VIEW ABSTRACT

682  Efficacy of liposomal nanocarriers in targeted delivery of ETB receptor agonist, IRL-1620 for the treatment of Alzheimer’s Disease. Presenter: B M Oesterling, Midwestern University, U.S.A.. Authors: B M Oesterling, A Gulati, M D Joshi. VIEW ABSTRACT

683  Efficacy of PLGA particle vaccine against house dust mite allergen depends on size of PLGA particles and presence of CpG. Presenter: V B Joshi, University of Iowa, U.S.A.. Authors: V B Joshi, A Dodd, X Jin, A Wongrakpanich, K Corley, P Thorne, A Salem. VIEW ABSTRACT

684  Enhanced in vivo CTL activity by newly synthesized micelles  loaded with Trp2 peptide. Presenter: Q Zeng, West China School of Pharmacy, Sichuan University, China. Authors: Q Zeng. VIEW ABSTRACT

686  Formulation and Evaluation of therapeutic vaccine microparticles for Breast Cancer. Presenter: N Mulla, Mercer University, U.S.A.. Authors: N Mulla, L Chablani, A Parenky, M J D'Souza. VIEW ABSTRACT

687  Formulation and Packaging Optimization for Microneedle Delivery of Abaloparatide, a Novel Peptide for Treatment of Osteoporosis. Presenter: Y Zhang, 3M Drug Delivery Systems Division, U.S.A.. Authors: Y Zhang, K Brown, K Siebenaler, J Moseman, T Fenn, D Dohmeier, K Hansen, G Hattersley. VIEW ABSTRACT

688  Generation of a bispecific antibody (EphA10/CD3) as a novel biodrug candidate against breast cancer. Presenter: S Taki, Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan., Japan. Authors: S Taki, H Kamada, K Nagano, Y Mukai, Y Tsutsumi, S Tsunoda. VIEW ABSTRACT

690  In vivo inhibition of hepatitis C virus infection by anti-human claudin 1 monoclonal antibodies. Presenter: M Iida, Osaka University, Japan. Authors: M Iida, S Nagase, M Yamashita, Y Shirasago, M Fukasawa, M Tada, A Ishii, A Watari, K Yagi, M Kondoh. VIEW ABSTRACT

691  Intra-Articular injection of a Hyaluronic acid - Salmon Calcitonin Conjugate as Potential Treatment of Osteoarthritis. Presenter: G Pasut, University of Padua, Italy. Authors: A Mero, M Campisi, D Renier, M Favero, C Barbera, G Pasut. VIEW ABSTRACT

693  Lamellar to cubic phase transitions: Tackling the bioactive frontier. Presenter: T Hartnett, CSIRO/University of Melbourne, Australia. Authors: T Hartnett, K Ladewig, P G Hartley, A J O'Connor, K M McLean. VIEW ABSTRACT

694  Lipid-based Nanoparticles Co-loaded with Tumor Cell Lysate and Immunostimulatory Agents for Cancer Immunotherapy. Presenter: L J Ochyl, University of Michigan, U.S.A.. Authors: L J Ochyl, J J Moon. VIEW ABSTRACT

695  Maximising the Half-Life of Bone Morphogenetic Protein (BMP) using Sustained Release Calcium Phosphate Microcrystals. Presenter: J Vos, XstalBio Ltd, United Kingdom. Authors: C MacLeod, J Vos, B D Moore. VIEW ABSTRACT

696  Melittin-GST fusion protein and hyaluronic acid have augmented anti-inflammatory properties when combined. Presenter: J E Rayahin, University of Illinois at Chicago, U.S.A.. Authors: J E Rayahin, J S Buhrman, R A Gemeinhart. VIEW ABSTRACT

697  Microgels for the Controlled Release of Proteins. Presenter: J L Rios, Cornell University, U.S.A.. Authors: J L Rios, G Lu, N Seo, T Lambert, D Putnam. VIEW ABSTRACT

698  Microparticle-Mediated Delivery of Growth Factors Promotes Cardiac Repair in Infarcted Rats . Presenter: F R Formiga, State University of Pernambuco (UPE), Biotech Laboratory, 55294-902, Garanhuns-PE, Brazil; State University of Pernambuco (UPE), Applied Cellular and Molecular Biology Program, Institute of Biological Sciences, 50100-130, Recife-PE, Brazil, Brazil. Authors: F R Formiga, M J Blanco-Prieto, F Prósper. VIEW ABSTRACT

699  Novel hollow microneedle technology for depth controlled microinjection-mediated dermal vaccination: a study with polio vaccine in rats. Presenter: J Bouwstra, Leiden Academic Centre for Drug Research, Leiden University, Netherlands. Authors: K van der Maaden, B Trietsch, P Schipper, H Kraan, G Kersten, E Varypataki, W Jiskoot, J Bouwstra. VIEW ABSTRACT

700  Novel Vaccine Delivery System Induces Robust Humoral and Cellular Immnune Responses Based on Multiple Mechanisms. Presenter: G Ma, Institute of Process Engineering, Chinese Academy of Sciences, China. Authors: G Ma, Y Wang, J Wu. VIEW ABSTRACT

701  pH responsive liposomes for enhanced local protein delivery to cancer tissues. Presenter: S Salmaso, Department of Pharmaceutical and Pharmacological Sciences, University of Padova - Italy, Italy. Authors: S Salmaso, M Vila, M de Bernard, G Codolo, E Ambrosio, S Bersani, P Caliceti. VIEW ABSTRACT

702  Physicochemical Characterization of an Endogenous Anti-ageing and Wound Healing Tripeptide GHK-Cu. Presenter: T Badenhorst, University of Auckland, New Zealand. Authors: T Badenhorst, D Svirskis, Z Wu. VIEW ABSTRACT

703  Phytantriol based novel crystalline self-assemblies for oral insulin delivery. Presenter: S Jain, National Institute of Pharmaceutical Education and Research (NIPER), India. Authors: S Jain, A K Agrawal, K K Gandrathi. VIEW ABSTRACT

704  Protein Crystallization for Delivery. Presenter: K Shi, Shenyang Pharmaceutical University, Taiwan. Authors: K Shi. VIEW ABSTRACT

706  Reversible and tunable PEGylation at Arginine residues. Presenter: Y Gong, ETH Zürich, Switzerland. Authors: Y Gong, J Leroux, M A Gauthier. VIEW ABSTRACT

707  Self-Encapsulating PLGA Microspheres: A Novel Method for Delivery of Vaccine Antigens. Presenter: B A Bailey, University of Michigan, U.S.A.. Authors: B A Bailey, K H Desai, S P Schwendeman. VIEW ABSTRACT

708  Short noncoding DNA fragments improve immune potency of electroporation mediated pCMV-EGFRvIII vaccination. Presenter: J Peng, Shanghai Jiao Tong University, China. Authors: J Peng, S Si, Y Xu. VIEW ABSTRACT

710  Subunit Vaccine Design of the Schistosomiasis Japonica Insulin Receptor. Presenter: R Stephenson, Univ of Queensland, Australia. Authors: R Stephenson, H You, D McManus, I Toth. VIEW ABSTRACT

711  The preparation and in vivo vaccination effects of PLGA emulsion gels. Presenter: Y Yang, Shanghai Jiao Tong University, China. Authors: Y Yang. VIEW ABSTRACT

712  Thermally triggered release of a pro-osteogenic peptide from a functionalized collagen-based scaffold using thermosensitive liposomes. Presenter: A Lopez-Noriega, Royal College of Surgeons in Ireland, Spain. Authors: A Lopez-Noriega, E Ruiz-Hernandez, E Quinlan, W E Hennink, F J O'Brien. VIEW ABSTRACT

Transdermal Delivery     [RETURN TO TOP]

713  A miniaturized instrument for rapid in vitro release testing of semi-solid formulations in pharmaceuticals: application to ibuprofen gel. Presenter: A Chapman, Paraytec Ltd, United Kingdom. Authors: A Chapman. VIEW ABSTRACT

714  A Predictive Microscopic Mathematical Diffusion Model for Finite Dose Skin Penetration: Extension of the Model Considering Stratum Disjunctum Layers. Presenter: M Heisig, Goethe University Frankfurt am Main, Germany. Authors: M Heisig, A Naegel, A Ehlert, T Hahn, U Schaefer, G Wittum. VIEW ABSTRACT

715  Adjustment of Needle-free Jet Injector Control to Account for Viscous Loss. Presenter: R M Williams, Auckland Bioengineering Institute, New Zealand. Authors: R M Williams, N Hogan, I W Hunter, P Nielsen, A Taberner. VIEW ABSTRACT

716  An Investigation of Cutaneous Absorption of Caffeine through Elderly Female Epidermis. Presenter: S Lee, Kimberly-Clark Corporation, U.S.A.. Authors: S Lee, P Sriwiriyanont, D Ambrose, M Solloway, D G Biggs. VIEW ABSTRACT

719  Comparative study of Different Skin Penetration Delivery Vehicles for Retinol, Resveratrol, Epigallocatechin gallate, and Vitamin C. Presenter: M Lopez Garcia, Kimberly Clark, U.S.A.. Authors: M Lopez Garcia, C Annelin, D Ambrose, D Devine. VIEW ABSTRACT

722  Effect of polymorphism on crystallization of donepezil in drug-in-adhesive matrix. Presenter: H Choi, Chosun University, Korea. Authors: G Lee, E Lee, J Ryoo, H Choi. VIEW ABSTRACT

724  Enhanced local delivery of topical anaesthetics. Presenter: A P Raphael, The University of Queensland, Australia. Authors: A P Raphael, E J Payne, M Maestracci, H Soyer, T W Prow. VIEW ABSTRACT

725  Enhanced Transdermal Adsorption of L-DOPA with Glycerol Dendrons. Presenter: T Ooya, Kobe University, Japan. Authors: T Ooya, K Okada, T Takeuchi. VIEW ABSTRACT

726  Epidermis-target by iontophoresis of ovalbumin-loaded liposomes for transcutaneous immunization. Presenter: D S Bernardi, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil. Authors: D S Bernardi, B T Perusso, R F Lopez. VIEW ABSTRACT

728  Evaluation of a Transdermal Murine Breast Cancer Vaccine administered via Micro-needles. Presenter: N S Mulla, Mercer University, U.S.A.. Authors: L Chablani, N S Mulla, A Akalkotkar, S A Tawde, M J D'Souza. VIEW ABSTRACT

729  Evaluation of antifungal activity of some propiconazole nitrate gels. Presenter: E A Popa, Rite Aid Pharmacy, U.S.A.. Authors: E A Popa, I Popovici, O Dorneanu, L Ochiuz. VIEW ABSTRACT

730  Formulation and Evaluation of Transdermal Microparticulate Vaccine for Ovarian Cancer. Presenter: R P Gala, Mercer University, U.S.A.. Authors: R P Gala, S A Tawde, L Chablani, M J D'Souza. VIEW ABSTRACT

731  Formulation of Cationic Niosomes for Dermal Delivery of an Endogenous Anti-aging Tripeptide Using a Post-insertion Technique. Presenter: T Badenhorst, University of Auckland, New Zealand. Authors: T Badenhorst, D Svirskis, Z Wu. VIEW ABSTRACT

733  Improved Terbinafine Formulations, Based on Third Generation Deformable Vesicles, for Noninvasive Topical Application and Superficial Mycoses Therapy. Presenter: M Elsayed, Department of Pharmaceutics, Faculty of Pharmacy, Alexandria University, Egypt. Authors: G Cevc, M Elsayed. VIEW ABSTRACT

734  In Vitro Drug Release and In Vivo Efficacious Study of Lyogels Containing Hydrocortisone for the Treatment of Eczema. Presenter: S Ng, Centre for Drug Delivery Research, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Malaysia. Authors: S Ng, N Anuwi, T Tengku-Ahmad. VIEW ABSTRACT

735  Intradermal RNAi therapeutic system by novel class of RNAi agents and functional peptide for atopic dermatitis. Presenter: T Kanazawa, Tokyo University of Pharmacy and Life Sciences, Japan. Authors: T Kanazawa, T Hamasaki, Y Seta, T Ohgi, H Okada. VIEW ABSTRACT

736  Optimization of Dissolving Microneedle Formulations Using Dissolution Rate Studies. Presenter: J Kennedy, Queens University Belfast, United Kingdom. Authors: J Kennedy, R F Donnelly. VIEW ABSTRACT

737  Penetration and Distribution Studies of Sensitive Nanoparticles to the pH of the Skin: Targeting the Follicular Pathway. Presenter: I O Calderón-Lojero, Facultad de Estudios Superiores Cuautitlán, UNAM, Estado de México, C.P. 54714, México, Mexico. Authors: C L Domínguez-Delgado, P Serrano-Castañeda, I O Calderón-Lojero, J J Escobar-Chávez, Y N Kalia, F A Ganem-Rondero. VIEW ABSTRACT

738  Preparation of Redispersible Liposomal Dry Powder by an Ultrasonic Spray Freeze Drying Technique for Transdermal Delivery of EGF. Presenter: X Zhang, Shanghai Institute of Materia Medica, China. Authors: F Yin, S Guo, Y Gan, X Zhang. VIEW ABSTRACT

740  Thermoresponsive nanogels based on hyperbranched polyglycerol for dermal protein delivery. Presenter: M A Molina Soler, Freie Universitat Berlin, Germany. Authors: M A Molina Soler, M Witting, W Frieß, S Küchler, M Calderón. VIEW ABSTRACT

741  Topical Delivery of Macromolecules to the Breast through Nipple-Areola Complex. Presenter: K Dave, Department of Pharmaceutical Sciences, South Dakota State University, U.S.A.. Authors: K Dave, O Perumal. VIEW ABSTRACT

742  Transdermal delivery of pravastatin sodium in transdermal patches using solid microneedles. Presenter: I O Calderón Lojero, UNAM, Mexico. Authors: I O Calderón Lojero, P Serrano Castañeda, J J Escobar Chávez, O R Guadarrama Escobar, J Arroyo Vázquez, L M Melgoza Contreras. VIEW ABSTRACT

743  Transdermal Hyaluronate-Myostatin Peptide Conjugate for the Treatment of Muscular Dystrophy. Presenter: W Kong, POSTECH, Korea. Authors: W Kong. VIEW ABSTRACT

 

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