July 16-19, 2017
The 2017 CRS Annual Meeting presentations are available to CRS members. Non-member annual meeting attendees have access for one year following the annual meeting for viewing.
Controlled Drug Delivery Systems and the Creation of New Medical Treatments
Dr. Robert Langer, Massachusetts Institute of Technology, U.S.A.
Advanced drug delivery systems are having an enormous impact on human health. The presentation will start by discussing Langer Lab’s early research on developing the first controlled release systems for macromolecules and the isolation of angiogenesis inhibitors (enabled by using these delivery systems) and how these led to numerous new therapies. This early research then led to new drug delivery technologies, including nanoparticles and nanotechnology, that are now being studied for use in treating cancer and other illnesses and for use in vaccine delivery. We will then discuss ways of developing novel microchips for drug delivery and developing new super-long acting oral delivery systems that can deliver drugs to combat diseases in the developing world. Approaches for synthesizing new biomaterials, such as biodegradable polyanhydrides, will be examined, and examples where such materials are used in brain cancer and other diseases will be discussed. Finally, by delivering mammalian cells, including stem cells, with synthetic polymers, new approaches for engineering tissues are being developed that may someday help in various diseases. Examples in the areas of cartilage, skin, blood vessels, and spinal cord repair will be discussed.
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