Integrated Glucose Sensing and Insulin Delivery Based on Hydrogels, Chips, and Block Polymers

Ronald A. Siegel

Departments of Pharmaceutics and Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455, USA
siege017@umn.edu

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ABSTRACT SUMMARY
We review a set of hydrogel, microfabrication, and block polymer studies aimed constructing a miniaturized implantable glucose sensor that can be queried by remote radio frequency (RF) stimulation. The device features integration across the supramolecular, nano- and microscales, with no internal power source or transcutaneous components. The device can be modified to provide simple, closed loop insulin delivery.

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