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Fundamentals and Applications of Controlled Release Drug Delivery covers the fundamentals relating to the science and technology of drug delivery. The book is written at a level that is understandable to those entering the field and who are not familiar with its common phrases or complex terms. It is a book that provides a simple encapsulation of concepts and expands on them using a building block approach to each subject, starting at a basic level and building to extend the readers knowledge and application of the subject. In each chapter the basic concept is explained as simply and clearly as possible without a great deal of detail, then in subsequent sections additional material is introduced in order to build up the reader’s understanding and comprehension of the subject matter.
This book will be indispensable to scientists interested in the science and technology of drug delivery and be essential for those developing delivery systems designed to improve the clinical performance of a drug.
Siepmann, Juergen; Siegel, Ronald A.; Rathbone, Michael J. (Eds.)
1st Edition, 2012, XIII, 592 p.
Hardcover, ISBN 978-1-4614-0880-2
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Long Acting Injections and Implants includes the historical development of the field, drugs, diseases and clinical applications for long acting injections and implants, anatomy and physiology for these systems, specific injectable technologies (including lipophilic solutions, aqueous suspensions, microspheres, liposomes, in situ forming depots and self-assembling lipid formulations), specific implantable technologies (including osmotic implants, drug eluting stents and microfabricated systems), peptide, protein and vaccine delivery, sterilization, drug release testing and regulatory aspects of long acting injections and implants.
This volume provides essential information for experienced development professionals but was also written to be useful for scientists just beginning work in the field and for others who need an understanding of long acting injections and implants. This book will also be ideal as a graduate textbook.
Wright, Jeremy C.; Burgess, Diane J. (Eds.)
1st Edition, 2012, XV, 557 p.
Hardcover, ISBN 978-1-4614-0553-5
Controlled Release in Oral Drug Delivery delves into the subject matter and its challenges with great detail. Authors have been drawn from academia, providers of excipients and from those designing controlled release systems in industrial R&D and manufacture. The contents provide a unique blend of cutting edge knowledge, data on materials and practical experiences. It is essential text for students, researchers and industrial engineering, formulation and manufacturing technologists as well as quality testing and control functions.
Controlling the rate, extent and time of a drug’s delivery can optimize its performance in many ways, relative to “immediate release” delivery. Such optimized design requires a broad knowledge base of topics such as gastro intestinal tract physiology, polymer science, and the mechanisms by which drugs are released from the formulated units. Technologies to “reduce to practice” also need to be carefully considered. Such knowledge must be allied to the physico chemical properties of the drug, its pharmacokinetic behaviors, enzyme susceptibility and other factors that can affect absorption or timecourse in the biosystem.
Wilson, Clive G.; Crowley, Patrick J. (Eds.)
2011, XIII, 412 p. 142 illus., 63 in color.
Hardcover, ISBN 978-1-4614-1003-4
Controlled Pulmonary Drug Delivery is the first book in the CRS “Advances in Delivery Science and Technology” Series. This book is published in partnership with Springer and was released in July 2011. This distinctive text provides a toolbox for pharmaceutical scientists and those involved in product development utilizing pulmonary drug delivery systems. Uniquely focusing on aspects of control, both temporal and spatial, the text collects a broad range of interlinked chapters that provide both theoretical and practical insight.
This volume will be of interest to scientists and engineers developing pulmonary drug delivery systems. The unique themes of controlled release science and technology that run through the book ensure that experienced and newcomers will greatly benefit from this book. As the importance for control over therapeutic performance is better recognized and demanded, this text will be essential for those delivering bioactives to the lung.
Smyth, Hugh D.C.; Hickey, Anthony J. (Eds.)
1st Edition, 2011, XIII, 557 p.
Hardcover, ISBN 978-1-4419-9744-9