Khaled Greish and Hiroshi Maeda. Department of Microbiology, Jumamoto University. Department of Pharmaceutics, Sojo University, Japan.
This presentation describes the use of permeability and retention effect to target anti-cancer drugs selectively and how styrene maleic acid-miceller drugs enhance the effect. The AUC of this micelle is more than 40% higher than free THP and 13 times better in tumor concentration.