Integrated Glucose Sensing and Insulin Delivery Based on Hydrogels, Chips, and Block Polymers

Ronald A. Siegel

Departments of Pharmaceutics and Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455, USA


We review a set of hydrogel, microfabrication, and block polymer studies aimed constructing a miniaturized implantable glucose sensor that can be queried by remote radio frequency (RF) stimulation. The device features integration across the supramolecular, nano- and microscales, with no internal power source or transcutaneous components. The device can be modified to provide simple, closed loop insulin delivery.

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