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Nominations now being accepted for the 2012 CRS Board election. As a Controlled Release Society member, you are invited to help shape the future of CRS leadership. Nominations are due February 6, 2012 for the Secretary, Treasurer and Directors-At-Large positions. View information on the CRS Board nomination process.
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Microbubble ultrasound-guided targeted delivery to tumors
Cancer gene therapy remains a promising approach to treating a variety of malignancies by inducing tumor cells to generate gene products that kill cancer cells without hurting healthy tissue. However, cancer gene therapy, as well as gene therapy for other diseases, has been restricted by the difficulty of safe and effective delivery of DNA into the cytoplasm of tumor cells. There are basically two main barriers to overcome. The first is the lack of effective means of systemic targeting, i.e., targeted delivery of the injected DNA to the tumor and homogeneous accumulation throughout the tumor tissue. The second is the poor control of intracellular targeting, i.e., transport of DNA to the nucleus, where it can be transcribed. In this issue, two new important developments to overcome these barriers using ultrasound-guided targeting with microbubbles are described to facilitate cancer gene therapy. |
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Building on Our Success
As we enter “the season of mists and mellow fruitfulness” in the UK, it is time to look ahead with some anticipation to new activities and experiences. CRS is a remarkably diverse, multidisciplinary and global society that plans to continue to build on the successes of the last few years in growing our society and improving the services that we provide.
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CRS Vision Statement: Visionary leadership in delivery science and technology.
CRS Mission Statement: CRS is an international, multidisciplinary society dedicated to delivery science and technology.
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