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Cell Derived Nano-Ghosts: A Novel Targeted Gene Delivery System For Cancer Therapy

We present here with a novel non-viral targeted gene delivery system termed "Nano-Ghosts" (NG), which is based on vesicles made from mesenchymal stem cells (MSCs) cytoplasmic membrane. Our study shows a significant in vitro inhibitory effect of prostate cancer cells and a dramatic in vivo tumor inhibition in nude mice after only a single IV administration of the NG-DNA. Multiple NG-DNA administration resulted in an even stronger effect then a single dose.  Learn more

 Drug Delivery and Translational Research (DDTR)

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