Welcome to Controlled Release Society

A Japanese proverb states, “Planning without action is a daydream. Action without planning is a nightmare.” Yet, despite the fact that most of us know and understand the importance of planning, many of us dread it. For some, it is the word “strategic” that creates a seeming burden—the belief that such planning requires omniscience or unique insight.

Inside Track

The Development of Somatuline Autogel®: An Interview with Joël Richard, Vice President Peptides, Ipsen

Somatuline Autogel® is a ready-to-use sustained release formulation of the peptide lanreotide with a unique and innovative controlled release mechanism. Andy Lewis interviewed Joël Richard, VP Peptides at Ipsen, on the background of its development, how it works, and how it is manufactured.

DDTR Featured Article

Glyceryl monooleate-coated bioadhesive hollow microspheres of riboflavin for improved gastroretentivity: optimization and pharmacokinetics

The bioadhesive hollow microspheres of riboflavin were developed as a site-specific gastroretentive system to prolong the residence time of drug in the stomach and, consequently, to enhance the bioavailability. Hollow microspheres (M1–M9) prepared by the emulsion solvent diffusion method using ethyl cellulose and Eudragit E100 as shell-forming polymers were designed using 32 full factorial design. The optimized formulation (M5) with 93.23 ± 0.6 % entrapment efficiency and 75.39 ± 3.4 % cumulative drug release at 8 h was subjected to coating with a bioadhesive layer of glyceryl monooleate (GMO) to obtain BM5.

CRS Vision Statement:
Visionary leadership in delivery science and technology.
CRS Mission Statement:
CRS is an international, multidisciplinary society dedicated to delivery science and technology.

CRS Recommends

European Inventor Award 2013
Patrick Couvreur and his colleagues Barbara Stella, Véronique Rosilio, and Luigi Cattel have been awarded the European Inventor Award 2013 in “Research”. This is a milestone for the entire field of delivery science. Learn more

Announcements

From the President

Strategic Planning Is a State of Mind

Around the Globe

Inside Track

The Development of Somatuline Autogel®: An Interview with Joël Richard, Vice President Peptides, Ipsen

DDTR Featured Article

CRS Recommends