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Hear From Plenary Speaker Vladimir Torchilin. This year's meeting will feature 3 outstanding plenary speakers that will offer a unique variety of innovative and thought-provoking subjects, including Vladimir Torchilin, Northeastern University. Listen as Professor Torchilin previews his plenary on Targeting Cell Organelles.
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Chapters Build the Future
Modern-day science is by its very nature collaborative. Biomedical research illustrates this point, as it embraces the chemical, biological, engineering, medical, and physical sciences. Such multidisciplinary research knows no international boundaries. |
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Interview with the Rajesh Kumar (Alkermes) on the Development of Bydureon™
Bydureon (exenatide extended-release for injectable suspension) is now approved by the U.S. FDA and in various territories outside the United States. For many people, trying to maintain the appropriate blood sugar (glucose) levels day after day can be frustratingly difficult. Other formulations of GLP-1 receptor agonists require twice-daily or once-daily administration. In contrast, Bydureon only needs to be self-administered once a week. |
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Drug release from nanomedicines: selection of appropriate encapsulation and release methodology The characterization of encapsulation efficiency and in vitro drug release from nanoparticle-based formulations often requires the separation of nanoparticles from unencapsulated drug. Inefficient separation of nanoparticles from the medium in which they are dispersed can lead to inaccurate estimates of encapsulation efficiency and drug release. This study establishes dynamic light scattering as a simple method for substantiation of the effectiveness of the separation process. Colistin-loaded liposomes, as an exemplar nanosized delivery particle, were diluted to construct a calibration curve relating the amount of light scattering to liposome concentration. Dynamic light scattering revealed that, in the case of ultracentrifugation and centrifugal ultrafiltration, approximately 2.9% of the total liposomes remained in supernatants or filtrates, respectively. |
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CRS Vision Statement:
Visionary leadership in delivery science and technology.
CRS Mission Statement:
CRS is an international, multidisciplinary society dedicated to delivery science and technology.
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A Model to Predict Drug Encapsulation Inside Unilamellar Liposomes
Developed in Burgess Laboratory, this web application was written to facilitate the use of a novel mathematical model. Learn more. |
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