Integrated Glucose Sensing and Insulin Delivery Based on Hydrogels, Chips, and Block Polymers.

Year
2010
Authors
Ronald A. Siegel
Institutions
Departments of Pharmaceutics and Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455, USA, siege017@umn.edu
Summary

We review a set of hydrogel, microfabrication, and block polymer studies aimed constructing a miniaturized implantable glucose sensor that can be queried by remote radio frequency (RF) stimulation. The device features integration across the supramolecular, nano- and microscales, with no internal power source or transcutaneous components. The device can be modified to provide simple, closed loop insulin delivery.