About CRS

messageCRS is the home for experts dedicated to delivery science, including delivery scientists, engineers, clinicians, and technical professionals. CRS members are        creating the future of delivery science and technology through fundamental delivery research, development, regulatory science, and clinical translation. Research published in CRS journals and presented during the Annual Meeting & Exposition offers a breadth of scientific knowledge covering new technologies and science in the multi-disciplinary delivery field.

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New This Month

 CRS College of Fellows Nominations - EXTENDED!

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CRS Awards Nominations - EXTENDED!

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CRS 2022 Annual Meeting
Registration and Abstract Submissions - OPEN!

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 Click here to submit an abstract

CRS 2022 Annual Meeting

Drug Delivery and Translational Research (DDTR)

DDTR Video

Prof. Ben Boyd, incoming President of the CRS and Editor of DDTR, talks about his experience with the DDTR, an official journal of the CRS.

Inspirational Note

Inspirational note by Dr. Andrew L. Lewis

Development and approval of rybelsus (oral semaglutide): ushering in a new era in peptide delivery

In this Inspirational Note, Dr. Andrew Lewis and coauthors feature an amazing and innovative discovery that is changing the paradigm of oral peptide delivery.

 

Mansoor Amiji

 Inspirational note by Drs. Lara Milane and Mansoor Amiji

Clinical approval of nanotechnology-based SARS-CoV-2 mRNA vaccines: impact on translational nanomedicine

In this Inspirational Note, Drs. Lara Milane and Mansoor Amiji share their insights and reflections on the impact of the recently approved SARS-CoV-2 mRNA vaccines on the present and future of translational nanomedicines.

 

A. Florence

Inspirational note by Alexander (Sandy) T. Florence  Trajectories in nanotechnology: embracing complexity, seeking analogies

"A timely and truly insightful Inspirational Note by one of the fathers of nanotechnology & pharmaceuticals.”  -Jung Soo Suk, Ph.D., Assistant Professor, The Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine

 

Inspirational Note from Dr. Marianne Ashford, Senior Principal Scientist in Glocal Advanced Drug Delivery Group in Pharmaceutical Sciences at AstraZeneca "Drug delivery - the increasing momentum"  

"In this 'Inspirational Note' you will be inspired by the way industry sees advances in drug delivery and Nanomedicine. Dr. Marianne Ashford talks about the 'increasing momentum'. You should not miss this note if you are interested in translational research." -Prof. Maria José Alonso, Editor-in-Chief of the Drug Delivery and Translational Research (DDTR) Journal, Past President of the Controlled Release Society

 

Inspirational Note from Dr. Robert Langer

"From micro to nano: evolution and impact of drug delivery in treating disease"

In this Inspirational Note, Robert Langer and Jeff Hrkach highlight the technological evolution of drug delivery from micro to nano, providing examples of clinically approved medicines that demonstrate the significant impact of the drug delivery field on treating many diseases.

 


Latest Issue of DDTR: January 2022

DDTR January 2022

Best Paper of the January 2022 Issue of DDTR: 
SummaryDrug delivery to the inner ear is challenging due to its location in the petrous bone, small volume, and tight barriers. Localized (i.e., intracochlear) delivery of drugs would overcome the limitations of extracochlear drug delivery. The study focuses on the development of small, flexible, and biodegradable PLGA-based implants for controlled intracochlear drug delivery and release. The drug carrier system was tested for implantation in the human inner ear in temporal bones. In some of these temporal bones, cochlear implants were implanted before the insertion of the drug carrier system. Afterwards, temporal bones were imaged by ultra-high-resolution computed tomography to evaluate the placement of the drug carrier system and cochlear implant electrodes. The measurements revealed the feasibility of implanting the drug carrier system into the scala tympani of the human inner ear and further the possibility of co-administration with a cochlear implant.


DDTR 2020 Best Paper

2020 DDTR Best Paper of the Year: Translational studies of intravenous and intracerebroventricular routes of administration for CNS cellular biodistribution for BMN 250, an enzyme replacement therapy for the treatment of Sanfilippo type B.

2019 DDTR Best Paper of the Year: Depletion of collagen by losartan to improve tumor accumulation and therapeutic efficacy of photodynamic nanoplatforms

The Best Paper is chosen by the DDTR Editorial Board.

2019 CRS Nanomedicine and Nanoscale Delivery (NND) Best Paper of the Year: Tumor growth inhibition by mSTEAP peptide nanovaccine inducing augmented CD8+ T cell immune responses

2019 DDTR CRS Oral Drug Delivery Focus Group Paper of the Year Award: Loratadine self-microemulsifying drug delivery systems (SMEDDS) in combination with sulforaphane for the synergistic chemoprevention of pancreatic cancer

 

 

Editor-in-Chief Article

Drug Delivery and Translational Research is a journal published by CRS, providing a unique forum for the scientific publication of high-quality research that is exclusively focused on translational aspects of drug delivery. The journal is published 6 times a year and will be available online to CRS members as part of their annual dues.

Drug Delivery and Translational Research Editors

Drug Delivery and Translational Research Editorial Board

    

 

Women In Science

Celebrate International Day of Women and Girls in Science 2021 by watching an update from CRS WIS

 


Annual Meeting Women In Science Keynote 

Women in Science

The CRS WIS ran two very successful sessions during the virtual CRS2020 Annual Meeting. Prof. Alonso delivered a very inspirational talk about her career in science that prompted a lively Q&A session where participants could ask their questions live, triggering a collegial and warm atmosphere. We are super proud to announce that this year we had over 150 participants of different nationalities and seniorities, of which a fair amount were men, which we warmly welcome. This allowed a virtual mingling with women CRS past presidents, past Women in Science Award Winners, and peers.

Thank you all for making these sessions an outstanding success and especially thanks to Prof. Alonso for willingly sharing her legacy in science and her path to get there. We are looking forward to welcoming your ideas and experiences and to keep us all engaged. Please contact Ruth Schmid with any questions. We also hope to see you face-to-face in Montreal in 2021!