July 24 - 28, 2023
About CRS
CRS is the home for experts dedicated to delivery science, including delivery scientists, engineers, clinicians, and technical professionals. CRS members are creating the future of delivery science and technology through fundamental delivery research, development, regulatory science, and clinical translation. Research published in CRS journals and presented during the Annual Meeting & Exposition offers a breadth of scientific knowledge covering new technologies and science in the multi-disciplinary delivery field.
Featured Videos
CRS Leadership Video Series
An Update from the CRS Spain/Portugal Chapter President, Helena Florindo
An Update from the CRS Chinese Taipei Local Chapter President, Hsin-Cheng Chiu
An Update from the CRS ED&I Committee Program Director, Morgan DiLeo
Featured Events
New This Month
CRS 2022 Annual Meeting
Drug Delivery and Translational Research (DDTR)
What's New?
October 2022 Issue
Best Paper of the October 2022 Issue of DDTR:
Summary: Systemic Injection of polyethylene glycol (PEG)-modified nanomedicines can promote accelerated clearance of the next dose of PEGylated nanomedicines via the accelerated blood clearance (ABC) phenomenon. It has been reported the interface between the PEG chain and the hydrophobic segment is the primary binding site recognized by anti-PEG IgM and responsible for increasing the liver uptake and shortening the circulation time of PEGylated nanomedicines. In this study, we demonstrate that the 1,2-distearoyl-snglycero-3-phosphoglycerol (DSPG) in PEGylated nanoemulsions (PEs) may mask this interface, thereby inhibiting the recognition and binding of PEs by anti-PEG IgM and weakening the ABC phenomenon of PEs. This finding provides a novel strategy to improve the pharmacokinetics and ultimately therapeutic efficacy of PEGylated nanocarriers.
Perspective
Role of drug delivery technologies in the success of COVID-19 vaccines: a perspective
This newly published DDTR “Perspective” article discusses the roles of drug delivery technologies in developing safe and efficacious vaccines. We thank Drs. Robert Langer, Pieter Cullis, Olivia Merkel and Mark Prausnitz for sharing their perspectives and insights on this important topic.
Inspirational Note
This newly released Inspirational Note discusses critical considerations for the clinical implementation of nanomedicine.
Inspirational note by Martin J. Whitaker, Hiep Huatan and Richard J. Ross
This Inspirational Note features innovative drug delivery technology that replicates the physiological cortisol diurnal rhythm for chronotherapy.
Inspirational note by James Goodson and Dr. Paul Rota
In this inspirational note, James Goodson and Dr. Paul Rota provide insightful and timely perspective and discussion regarding the importance of vaccine delivery technology and multidisciplinary efforts to achieve global vaccination and ultimately well-being.
Inspirational note by Dr. Andrew L. Lewis
Development and approval of rybelsus (oral semaglutide): ushering in a new era in peptide delivery
In this Inspirational Note, Dr. Andrew Lewis and coauthors feature an amazing and innovative discovery that is changing the paradigm of oral peptide delivery.
Inspirational note by Drs. Lara Milane and Mansoor Amiji
In this Inspirational Note, Drs. Lara Milane and Mansoor Amiji share their insights and reflections on the impact of the recently approved SARS-CoV-2 mRNA vaccines on the present and future of translational nanomedicines.
Inspirational note by Alexander (Sandy) T. Florence Trajectories in nanotechnology: embracing complexity, seeking analogies
"A timely and truly insightful Inspirational Note by one of the fathers of nanotechnology & pharmaceuticals.” -Jung Soo Suk, Ph.D., Assistant Professor, The Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine
Inspirational Note from Dr. Marianne Ashford, Senior Principal Scientist in Glocal Advanced Drug Delivery Group in Pharmaceutical Sciences at AstraZeneca "Drug delivery - the increasing momentum"
"In this 'Inspirational Note' you will be inspired by the way industry sees advances in drug delivery and Nanomedicine. Dr. Marianne Ashford talks about the 'increasing momentum'. You should not miss this note if you are interested in translational research." -Prof. Maria José Alonso, Editor-in-Chief of the Drug Delivery and Translational Research (DDTR) Journal, Past President of the Controlled Release Society
Inspirational Note from Dr. Robert Langer
"From micro to nano: evolution and impact of drug delivery in treating disease"
In this Inspirational Note, Robert Langer and Jeff Hrkach highlight the technological evolution of drug delivery from micro to nano, providing examples of clinically approved medicines that demonstrate the significant impact of the drug delivery field on treating many diseases.
2020 DDTR Best Paper of the Year: Translational studies of intravenous and intracerebroventricular routes of administration for CNS cellular biodistribution for BMN 250, an enzyme replacement therapy for the treatment of Sanfilippo type B.
2019 DDTR Best Paper of the Year: Depletion of collagen by losartan to improve tumor accumulation and therapeutic efficacy of photodynamic nanoplatforms
The Best Paper is chosen by the DDTR Editorial Board.
2019 CRS Nanomedicine and Nanoscale Delivery (NND) Best Paper of the Year: Tumor growth inhibition by mSTEAP peptide nanovaccine inducing augmented CD8+ T cell immune responses
2019 DDTR CRS Oral Drug Delivery Focus Group Paper of the Year Award: Loratadine self-microemulsifying drug delivery systems (SMEDDS) in combination with sulforaphane for the synergistic chemoprevention of pancreatic cancer
DDTR Videos
Drug Delivery and Translational Research is a journal published by CRS, providing a unique forum for the scientific publication of high-quality research that is exclusively focused on translational aspects of drug delivery. The journal is published 6 times a year and will be available online to CRS members as part of their annual dues.
Drug Delivery and Translational Research Editors
Drug Delivery and Translational Research Editorial Board
Women In Science
Visit the WIS Page
Update from Women in Science Chair, Maria Jose Alonso
Annual Meeting Women In Science Keynote
The CRS WIS ran two very successful sessions during the virtual CRS2020 Annual Meeting. Prof. Alonso delivered a very inspirational talk about her career in science that prompted a lively Q&A session where participants could ask their questions live, triggering a collegial and warm atmosphere. We are super proud to announce that this year we had over 150 participants of different nationalities and seniorities, of which a fair amount were men, which we warmly welcome. This allowed a virtual mingling with women CRS past presidents, past Women in Science Award Winners, and peers.
Thank you all for making these sessions an outstanding success and especially thanks to Prof. Alonso for willingly sharing her legacy in science and her path to get there. We are looking forward to welcoming your ideas and experiences and to keep us all engaged. Please contact Ruth Schmid with any questions. We also hope to see you face-to-face in Montreal in 2021!
