Category
Imaging and Characterization Techniques for Drug Delivery: Systems and Targeted Drug Delivery
Year
2013
Institutions
School of Mechanical Engineering; Department of Pharmaceutics; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, 47907, USA
Summary
A new tumor model is developed using microfluidics and tissue engineering technology in order to simulate the complex in vivo tumor microenvironment including vasculature, interstitium and lymphatics. The developed model, referred as to the tumor-microenvironment-onchip (TMOC), can mimic highly dynamic, interconnected and spatiotemporally varying tumor microenvironment and allows systematic characterization of nanoparticles (NPs) transport around tumors.
