This article summarizes selected patents in the area of controlled release or delivery that were published from March 3, 2026, through June 2, 2026. Greater detail on each of these patents is given on the U.S. patent website Patent Public Search | USPTO
General/Industrial Applications
US- 12617952 B1- Self-ameliorate-fissure-responsive Pod System For Alkyd-polyester Aircraft Runway Paint
An alkyd-polyester paint with fissure-responsive microcapsules containing epoxy resin, polythiol, hypervalent iodine, diamine, photoinitiator, and phosphine, enabling self-healing properties.
US- 20260096991- BIODEGRADABLE MICROCAPSULES AND METHOD FOR THEIR PREPARATION
The invention describes methods for preparing microcapsules with a broad set of applications including pharmaceuticals, foods, agriculture, fragrances, and nutraceuticals.
Agriculture
US- 20260137080- EARLY APPLICATIONS OF ENCAPSULATED ACETAMIDES FOR REDUCED INJURY IN CROPS
The disclosure describes methods for weed control using encapsulated acetamide herbicides with two distinct populations of microencapsulated acetamide herbicide. This approach reduces crop injury while improving pre-plant and pre-emergence application efficacy.
Diagnostic/Sensing
US- 12644885 B2- FLUORESCENT MICROSPHERES EVENLY COATED WITH MAGNETIC PARTICLES AND METHODS OF USE
This patent revolves around the generation of magnetic or fluorescent microspheres with cores coated by magnetic particle monolayers with broad applications in sensing.
US- 20260085345- MICROSPHERE FORMULATION FOR NUCLEIC ACID AMPLIFICATION, AMPLIFICATION METHOD, AND USE IN JOINT DETECTION
A microsphere formulation for nucleic acid amplification that exhibits increased sensitivity.
Pharma
US- 20260144877 - HIGH CAPACITY DIKETOPIPERAZINE MICROPARTICLES AND METHODS
Description of diketopiperazine microparticles having high capacity for adsorbing a drug or active agent. In particular, the diketopiperazine microparticles are formed using fumaryl diketopiperazine used for the treatment of disease or disorders by pulmonary delivery.
US- 20260144267- PROTEIN ENCAPSULATION OF NUTRITIONAL AND PHARMACEUTICAL COMPOSITIONS
Microencapsulation formulations with one or more hydrophobic materials encapsulated by one or more modified proteins / peptides with particle size controlled by a high shear process. The formulation can protect hydrophobic material from oxidative degradation and stabilize emulsions comprising a hydrophobic material.
US- 20260137831- POLYCAPROLACTONE MICROSPHERE PRE-DISPERSION COMPOSITION AND POLYCAPROLACTONE INJECTABLE GEL PREPARED FROM SAME
This polycaprolactone microsphere pre-dispersion formulation enables stable, and evenly dispersed microspheres resulting in a reduction in observed bubbles seen in other formulations. The use of this formulation in a gel carrier is also presented.
US- 20260124318- POLYMERIC MATERIAL AND PREPARATION METHOD THEREOF, AND DRUG-LOADING MATERIAL
A polymeric drug-loading material consisting of a crosslinked polymer; and multiple polyelectrolytes, which are grafted onto the three-dimensional network structure of the crosslinked polymer containing multiple ionizable groups, allowing for high adsorption efficiency via electrostatic mechanisms.
US- 20260108581- COMPOSITIONS AND METHODS FOR MICROSPHERE DELIVERY OF CARNOSINE FOR TREATMENT OF NEURODEGENERATIVE DISEASES AND DISORDERS
Compositions and methods for microsphere delivery of carnosine for treatment of neurodegenerative diseases.
US- 20260091149- SUSPENSION CONTAINING RADIOACTIVE MICROSPHERES, AND PREPARATION METHOD THEREFOR AND USE THEREOF
A resin microsphere with a radionuclide loaded on the surface, with an average particle size of 25 to 40 μm with anticancer applications.
US- 20260083680- MESOPOROUS NANO-MAGNESIUM OXIDE FOR DRUG LOADING AND PREPARATION METHOD THEREOF
A 50 to 150 nm mesoporous nano-magnesium oxide particle capable of high drug loading by adsorption.
US- 20260083713- MULTILAYERED PHARMACEUTICALLY ACTIVE COMPOUND-RELEASING MICROPARTICLES IN A LIQUID DOSAGE FORM
This is a description of a controlled-release multilayer microparticle containing a pharmaceutically active compound. The microparticle can be used for oral administration or direct administration in the stomach.
Bio
US- 20260114855- ENVIRONMENTALLY SENSITIVE BACTERIA-CAPTURING MICROPARTICLES
A description of pH-sensitive polyamide polymer-coated microparticles, that selectively captures bacteria at a pH less than 6.
US- 20260062679- HEPARINIZED MICROSPHERE, METHOD OF PREPARING THEREOF AND METHOD OF ISOLATING EXOSOMES
A heparinized microsphere comprised of a polymer, heparin, and a cross-linking agent. A method of isolating/purifying exosomes using the microsphere formulation is also provided.
Consumer Products/ Cosmetics
US- 12644076 B2 - PERFUME SYSTEM FOR PERFUMED CONSUMER PRODUCT
A perfume system comprised of core-shell microcapsules, and optionally, a free perfume oil for enhancing, conferring, increasing and/or modifying the fragrance properties and/or the fragrance intensity of perfumed consumer products.
US- 20260117082- DIGITAL PRINTING METHOD FOR MICROENCAPSULATED FRAGRANCE PRODUCT
A digitally manufactured scratch and sniff product containing microencapsulated fragrance varnish. The method involves printing a base image and then applying microcapsules with fragrance in designated places according to the printed image. The fragrance is then released by some sort of physical activation (like scratching!).
US- 20260108433- PLANT GLYCOSIDE MICROCAPSULE, AND PREPARATION METHOD AND APPLICATION
The present application belongs to the field of oral care materials such as toothpaste. Specifically, a plant glycoside microcapsule with a shell of the microcapsule of natural wax.
US- 20260076398- MICROPARTICLE COMPOSITIONS COMPRISING DIETARY FIBERS, METHODS OF MAKING, AND USE THEREOF
Microparticle compositions containing dietary fibers. Some fibers are for thickening and others are for bulking while others are prebiotic. One example particle formulation contains chia mucilage, konjac glucomannan, psyllium husk, and inulin.
US- 20260069547- MICROCAPSULES, PROCESS FOR THE PREPARATION OF MICROCAPSULES AND USE OF
MICROCAPSULES FOR PERFUMING A CONSUMER PRODUCT
Description of formulations of perfumed particles for solid consumer product formulations such as textile care
products.
Observations/Thoughts/Trends/Musings
You may notice, Reader, that this patent watch is shorter than previous ones. For some reason, my search algorithm just didn’t seem to find as many patents published around encapsulation as previous searches. This may be due to the higher numbers of patents I observed in the previous few patent watches. Or, it could be a reflection of world events as research budgets shrink. The year is half done. The warm summer breeze has already started here in Texas. That means it is time to prepare for the annual meeting. This time, it will be in beautiful Lisbon, Portugal. I hope to see you there. Please stop by the SwRI booth and say hello if you’re in town.
