Annual Meeting Archives

2018

Application of the ClassicDiels-Alder Reaction for Production of Antibody-Drug Conjugates
Presenters:
James Christie
Authors:
<b>J. Christie</b><sup>1</sup>, A. St. Amant<sup>2</sup>, F. Huang<sup>1</sup>, J. Lin<sup>1</sup>, D. Lemen<sup>1</sup>, S. Florinas<sup>1</sup>, S. Mao<sup>1</sup>, C. Fazenbaker<sup>1</sup>, H. Zhong<sup>1</sup>, J. Harper<sup>1</sup>, B. Vijayakrishnan<sup>3</sup>; <sup>1</sup>Medimmune, Gaithersburg, MD, <sup>2</sup>Univ. of California, Santa Barbara, CA, <sup>3</sup>Spirogen, Inc, London, United Kingdom
Institutions:
Medimmune
Applications Of Core-sheath Fiber Membranes Formed By Coaxial Electrospinning For Versatile Controlled Release Of Multiple Drugs
Category:
Manufacture, Characterization, Measurement, and Stability
Presenters:
Daewoo Han
Authors:
<b>D. Han</b>, A. Steckl; Univ. of Cincinnati, Cincinnati, OH
Institutions:
University of Cincinnati
Apply specific energy, stability, permeability and flowability of powder blend to predict table quality in scale up
Category:
Manufacture, Characterization, Measurement, and Stability
Presenters:
Yingjian Li
Authors:
<b>Y. Li</b><sup>1</sup>, H. Zhao<sup>1</sup>, D. Yang<sup>1</sup>, X. Guo<sup>1</sup>, J. Yin<sup>2</sup>; <sup>1</sup>Prinston Pharmaceutical Inc, Cranbury, NJ, <sup>2</sup>Freeman Technology, Wayne, PA
Institutions:
Prinston Pharmaceutical Inc
Asp49-phospholipase A<sub>2</sub>-loaded Liposomes As Experimental Therapy In Cutaneous Leishmaniasis Model
Category:
Delivery of Proteins, Peptides, and Vaccines
Presenters:
Roberto Nicolete
Authors:
N. B. de Barros<sup>1</sup>, S. R. A. Macedo<sup>1</sup>, A. S. Ferreira<sup>1</sup>, M. P. Tagliari<sup>1</sup>, L. D. F. Nicolete<sup>2</sup>, A. M. Soares<sup>1</sup>, <b>R. Nicolete</b><sup>2</sup>; <sup>1</sup>Fiocruz Rondônia, Porto Velho, Brazil, <sup>2</sup>Fiocruz Ceará, Fortaleza, Brazil
Institutions:
Fiocruz Ceará
Aspherical Bacteriomimetic Nanocarriers for Intracellular Infection Therapy
Category:
Micro- and nanoparticle Delivery
Presenters:
Sarah Gordon
Authors:
A. Castoldi<sup>1</sup>, <b>S. Gordon</b><sup>2</sup>, C-M. Lehr<sup>1</sup>; <sup>1</sup>Helmholtz Inst. for Pharmaceutical Res. Saarland, Saarbruecken, Germany, <sup>2</sup>Liverpool John Moores Univ., Liverpool, United Kingdom
Institutions:
Liverpool John Moores University
Assessing Formulation Attributes’ Impact On Local And Systemic Exposure Of Clindamycin After Topical Application Of Pro-Drug Clindamycin Phosphate Using PBPK Modelling
Category:
Topical and Transdermal Delivery
Presenters:
Sebastian Polak
Authors:
<b>S. Polak</b><sup>1</sup>, N. Patel<sup>2</sup>, K. Rowland-Yeo<sup>2</sup>, M. Jamei<sup>2</sup>; <sup>1</sup>Simcyp/Certara/Krakow Univ., Sheffield, United Kingdom, <sup>2</sup>Simcyp/Certara, Sheffield, United Kingdom
Institutions:
Simcyp/Certara/Krakow University
Assessing The Permeation Of Propranolol Hydrochloride Cream For Prospective Topical Treatment
Category:
Manufacture, Characterization, Measurement, and Stability
Presenters:
Hassan Elhassan
Authors:
E. Hart<sup>1</sup>, E. Baczkowski<sup>1</sup>, A. Price<sup>1</sup>, R. McLeod<sup>1</sup>, <b>H. Elhassan</b><sup>2</sup>, J. Birchall<sup>1</sup>; <sup>1</sup>Cardiff Univ., Cardiff, United Kingdom, <sup>2</sup>Univ. Hosp. Lewisham, London, United Kingdom
Institutions:
University Hospital Lewisham
Assessment Of Drug Gastrointestinal Supersaturation Using Two-stage <i>In Vitro</i> Dissolution Absorption System 2 - IDAS2
Category:
Manufacture, Characterization, Measurement, and Stability
Presenters:
Jibin Li
Authors:
<b>J. Li</b>, Y. Bukhtiyarov, N. Nessah, C. Hidalgo, Y. Huang, A. Owen, I. J. Hidalgo; Absorption Systems, Exton, PA
Institutions:
Absorption Systems
Association Of Guar-gum Hydrosoluble Films With Plga Nanoparticles For Buccal Delivery Of Therapeutic Peptides
Category:
Delivery of Proteins, Peptides, and Vaccines
Presenters:
Bruno Sarmento
Authors:
P. M. Castro<sup>1</sup>, <b>B. Sarmento</b><sup>2</sup>; <sup>1</sup>CBQF - Centro de Biotecnologia e Química Fina, Univ.e Católica Portuguesa, Oporto, Portugal, <sup>2</sup>Rua Alfredo Allen, Porto, Portugal
Institutions:
Rua Alfredo Allen
Back To Nature: Crafting A Gastric Resistant Coating From Naturally Occurring Materials
Category:
Oral Delivery for Food and Pharma
Presenters:
Rober Habashy
Authors:
<b>R. Habashy</b>, M. A. Alhnan; Univ. of Central Lancashire, Preston, United Kingdom
Institutions:
University of Central Lancashire
Bacteria-inspired Surface Modification With Polygammaglutamic Acid For Biocompatibility Of Nanomaterials
Category:
Micro- and nanoparticle Delivery
Presenters:
Gayong Shim
Authors:
<b>G. Shim</b>, D. Kim, J. Kim, M. Suh, Y-K. Oh; Seoul Natl. Univ., Seoul, Korea, Republic of
Institutions:
Seoul National University
BAR-Encapsulated And BAR-Modified Nanoparticles For Oral Biofilm Applications
Category:
Delivery of Proteins, Peptides, and Vaccines
Presenters:
Mohamed Mahmoud
Authors:
<b>M. Y. Mahmoud</b>, D. R. Demuth, J. M. Steinbach-Rankins; Univ. of Louisville, Louisville, KY
Institutions:
University of Louisville
Berberine Nanoparticles With Anti-alzheimer Potential: Effect Of Coating On Cerebrovascular Amyloid Targeting And Nanotoxicity<i></i>In Rats
Category:
Micro- and nanoparticle Delivery
Presenters:
Mohamed Nounou
Authors:
<b>M. I. Nounou</b><sup>1</sup>, S. Soudi<sup>2</sup>, S. Sheweita<sup>2</sup>, D. Ghareeb<sup>2</sup>, L. K. El-Khordagui<sup>2</sup>; <sup>1</sup>Univ. of Saint Joseph, West Hartford, CT, <sup>2</sup>Alexandria Univ., Alexandria, Egypt
Institutions:
University of Saint Joseph
Better In-Vivo Understanding of Ibuprofen Dissolution Using Bicarbonate Buffer
Category:
Manufacture, Characterization, Measurement, and Stability
Presenters:
Saqer Alarifi
Authors:
<b>S. Alarifi</b>, R. Loebenberg; Univ. of Alberta, Edmonton, AB, Canada
Institutions:
University of Alberta
Bioactive Mesoporous Silica Granulates Containing Doxorubicin And Metronidazole - Physicochemical Properties And Drug Release
Category:
Parenteral Controlled Release
Presenters:
Wiesław Sawicki
Authors:
<b>W. Sawicki</b>, K. Czarnobaj, M. Prokopowicz; Dept. of Physical Chemistry , Med. Univ. of Gdańsk, Gdańsk, Poland
Institutions:
Department of Physical Chemistry , Medical University of Gdańsk
Bioactivity Guided Fractionation and Compound Analysis of Papaya Extract Derived from Supercritical Carbon Dioxide
Category:
Manufacture, Characterization, Measurement, and Stability
Presenters:
Kooi Yeong Khaw
Authors:
<b>K. Khaw</b>, S. Pandey, E. Chua, C. Ang, M-O. Parat, P. Nicholas Shaw, J. Robert Falconer; The Univ. of Queensland, Brisbane, Australia
Institutions:
The University of Queensland
Bioavailable Curcumin - A Type 4 Lipid Based Drug Delivery System Using Gelucire<sup>®</sup>48/16 As Solid Solubilizer
Category:
Oral Delivery for Food and Pharma
Presenters:
Ketkee Deshmukh
Authors:
<b>K. Deshmukh</b><sup>1</sup>, S. Gurram<sup>1</sup>, C. Kapadia<sup>1</sup>, V. Jannin<sup>2</sup>, N. Farah<sup>2</sup>, K. Singh<sup>3</sup>; <sup>1</sup>Gattefosse India Pvt. Ltd., Mumbai, India, <sup>2</sup>Gattefosse SAS, Lyon, France, <sup>3</sup>SPPSPTM, NMIMS, Mumbai, India
Institutions:
Gattefosse India Pvt. Ltd.
Biocompatible Novel Tadalafil Nanoemulsion for Inhalation delivery
Category:
Regional Delivery
Presenters:
Sally Galal
Authors:
<b>S. Galal</b>, B. M. EL-bardissy, N. A. Boraie; Faculty of Pharmacy, Alexandris, Egypt
Institutions:
Faculty of Pharmacy
Biodegradable Hyperbranched Polyglycerol Based Iron Chelating System for the Treatment of Transfusional Iron Overload<i></i>
Category:
Micro- and nanoparticle Delivery
Presenters:
Srinivas Abbina
Authors:
<b>S. Abbina</b><sup>1</sup>, U. Abbasi<sup>1</sup>, M. Kalathottukaren<sup>1</sup>, J. N. Kizhakkedathu<sup>2</sup>; <sup>1</sup>Ctr. for Blood Res., Dept. of Pathology and Lab. Med., Univ. of British Columbia, Vancouver, BC, Canada, <sup>2</sup>Ctr. for Blood Res., Dept. of Pathology and Lab. Med., Dept. of Chemistry, Univ. of British Columbia, Vancouver, BC, Canada
Institutions:
Centre for Blood Research, Department of Pathology and Laboratory Medicine, University of British Columbia
Biodegradable Nanoparticles To Repurpose Disulfiram For Non-small Cell Lung Cancer (NSCLC) Treatment
Category:
Micro- and nanoparticle Delivery
Presenters:
Nishant Kulkarni
Authors:
<b>N. Kulkarni</b>; St. John's Univ., Jamaica, NY
Institutions:
St. John's University
Biodegradable Polymalic Acid Conjugated To Angiopep-2 And Tri-leucine Traverses The Blood-brain-barrier And Distributes Throughout The Mouse Brain
Category:
Micro- and nanoparticle Delivery
Presenters:
Liron Israel
Authors:
<b>L. L. Israel</b>, O. Braubach, A. Galstyan, A. Chiechi, E. Shatalova, Z. Grodzinski, H. Ding, K. L. Black, J. Ljubimova, E. Holler; Cedars Sinai Med. center, Los Angeles, CA
Institutions:
Cedars Sinai medical center
Biodistribution Of Polymeric Nanocapsules: Engineering Particles For Lymph Node Targeting<b></b>
Category:
Micro- and nanoparticle Delivery
Presenters:
Ana Cordeiro
Authors:
<b>A. S. Cordeiro</b><sup>1</sup>, J. Crecente-Campo<sup>1</sup>, M. de la Fuente<sup>2</sup>, S. F. González<sup>3</sup>, M. J. Alonso<sup>1</sup>; <sup>1</sup>Univ. of Santiago de Compostela, Santiago de Compostela, Spain, <sup>2</sup>Hlth.Res. Inst. of Santiago de Compostela (IDIS), Santiago de Compostela, Spain, <sup>3</sup>Inst. for Res. in Biomedicine, Università della Svizzera Italiana, Bellinzona, Switzerland
Institutions:
University of Santiago de Compostela
Biofunctionalization Of Gold Nanoparticle: A Model For Drug Delivery
Category:
Parenteral Controlled Release
Presenters:
Audrey Roth
Authors:
<b>A. Roth</b><sup>1</sup>, F. Murschel<sup>2</sup>, B. Liberelle<sup>1</sup>, G. De Crescenzo<sup>1</sup>, X. Banquy<sup>2</sup>; <sup>1</sup>Ecole Polytechnique, Montréal, QC, Canada, <sup>2</sup>Université de Montréal, Montréal, QC, Canada
Institutions:
Ecole Polytechnique
Biohybrid Multistage Nanovaccines for Melanoma
Category:
Delivery of Proteins, Peptides, and Vaccines
Presenters:
Hélder Santos
Authors:
F. Fontana, <b>H. Santos</b>; Univ. of Helsinki, Helsinki, Finland
Institutions:
University of Helsinki
Biopolymer Dots For Highly Efficient Photodynamic Therapy
Category:
Micro- and nanoparticle Delivery
Presenters:
Eunjung Choi
Authors:
<b>E. Choi</b>, H. Lee, E. Lee; Dept. of biology, The Catholic Univ. of Korea, Bucheon-si, Korea, Republic of
Institutions:
Department of biology, The Catholic University of Korea