Annual Meeting Archives

2018

Icos In β-cyclodextrin Nanosponges Inhibits The Growth Of Subcutaneous B16 Tumors
Category:
Delivery of Proteins, Peptides, and Vaccines
Presenters:
Roberta Cavalli
Authors:
<b>R. Cavalli</b><sup>1</sup>, C. Dianzani<sup>1</sup>, B. Ferrara<sup>1</sup>, N. Clemente<sup>2</sup>, E. Boggio<sup>2</sup>, L. Gigliotti<sup>2</sup>, F. Caldera<sup>1</sup>, F. Trotta<sup>1</sup>, M. Argenziano<sup>1</sup>, U. Dianzani<sup>3</sup>; <sup>1</sup>Univ. of Turin, Turin, Italy, <sup>2</sup>Univ. del Piemonte Orientale, Novara, Italy, <sup>3</sup>Univ. of Piemonte Orientale, Novara, Italy
Institutions:
University of Turin
Identification Of Cartilage Formation Ability Of Biodegradable Scaffold Containing TGF-b
Category:
Micro- and nanoparticle Delivery
Presenters:
Jeon Jeong Hwa
Authors:
<b>J. Jeong Hwa</b>; EHWA Univ., seoul, Korea, Republic of
Institutions:
EHWA University
Identification Of Hepatitis B Virus-derived Heparin-binding Domain: Application For Liposomal Drug Delivery
Category:
Micro- and nanoparticle Delivery
Presenters:
Qiushi Liu
Authors:
<b>Q. Liu</b>, M. Somiya, S. Kuroda; The Inst. of Scientific and Industrial Res., Osaka Univ., Ibaraki, Japan
Institutions:
The Institute of Scientific and Industrial Research, Osaka University
Image-guided Focused Ultrasound Ablation And Checkpoint Blockade For Targeted Metastatic Breast Cancer Immunotherapy
Category:
Regional Delivery
Presenters:
Natasha Sheybani
Authors:
<b>N. D. Sheybani</b>, A. R. Witter, A. Stevens, T. N. J. Bullock, R. J. Price; Univ. of Virginia, Charlottesville, VA
Institutions:
University of Virginia
Immunogene Therapy of Infections Using Fusogenic Porous Silicon Nanoparticles
Category:
Nucleic Acid Delivery
Presenters:
B.J. (Byungji) Kim
Authors:
<b>B. Kim</b>; Univ. of California, San Diego, La Jolla, CA
Institutions:
University of California, San Diego
Impact of Viscosity on Large Volume Subcutaneous Injection Pressure and Tissue Effect Resolution in an In Vivo Model
Category:
Delivery of Proteins, Peptides, and Vaccines
Presenters:
Wendy Woodley
Authors:
<b>W. D. Woodley</b><sup>1</sup>, S. S. Gerth<sup>1</sup>, D. R. Morel<sup>2</sup>, L. C. Chandler<sup>1</sup>, D. B. Sherman<sup>1</sup>, N. A. Oberlander<sup>3</sup>, R. J. Pettis<sup>1</sup>, N. G. Bolick<sup>1</sup>; <sup>1</sup>BD Technologies, Research Triangle Park, NC, <sup>2</sup>BD, Le Pont de Claix, France, <sup>3</sup>Charles River Lab., Research Triangle Park, NC
Institutions:
BD Technologies
Importance Of Comparative Dose Concentration In The Evaluation Of Complex Ophthalmic Suspension Product Equivalence
Category:
Manufacture, Characterization, Measurement, and Stability
Presenters:
Lynn Chen
Authors:
<b>L. Chen</b>, S. Manna, P. Petrochenko, B. Qin, D. Kozak, J. Zheng; U.S. Food and Drug Admin., White Oak, MD
Institutions:
U.S. Food and Drug Administration
Improved Trans-tympanic Delivery Of Levofloxacin Via Loading Into Polyethylene Glycol-decorated Nanoliposomes: <i>In Vitro </i>Characterization And <i>In Vivo</i> Assessment
Category:
Micro- and nanoparticle Delivery
Presenters:
Abdulaziz Al-mahallawi
Authors:
A. A. Abdelbary, <b>A. M. Al-mahallawi</b>, W. H. Abd-Elsalam; Faculty of pharmacy, Cairo Univ., Cairo, Egypt
Institutions:
Faculty of pharmacy, Cairo University
Improvement Of Cell Adhesion By Modification With Single-chain Antibody Via PEG-Lipid
Category:
Delivery of Proteins, Peptides, and Vaccines
Presenters:
Sota Yamada
Authors:
<b>S. Yamada</b>, Y. Higuchi, M. Hashida, F. Yamashita; Kyoto Univ., Kyoto, Japan
Institutions:
Kyoto University
In Situ Conditioning of Stem Cells for Enhanced Stem Cell Homing
Category:
Delivery of Proteins, Peptides, and Vaccines
Presenters:
Jye Yng Teo
Authors:
<b>J. Teo</b><sup>1</sup>, E. Ko<sup>1</sup>, J. Leong<sup>1</sup>, J. Hong<sup>2</sup>, J. Jeon<sup>2</sup>, Y. Yang<sup>3</sup>, H. Kong<sup>1</sup>; <sup>1</sup>Univ. of Illinois at Urbana-Champaign, Urbana, IL, <sup>2</sup>Korea Advanced Inst. of Sci. & Technology, Daejeon, Korea, Republic of, <sup>3</sup>Inst. of Bioengineering and Nanotechnology, Singapore, Singapore
Institutions:
University of Illinois at Urbana-Champaign
In Vitro Dissolution Testing Of Nanocrystalline Zileuton: Effect Of Drug Particle Size And Media pH
Category:
Oral Delivery for Food and Pharma
Presenters:
Rajan Jog
Authors:
<b>R. Jog</b>, D. J. Burgess; Sch. of Pharmacy, Univ. of Connecticut, Storrs, CT
Institutions:
School of Pharmacy, University of Connecticut
In Vitro Effect of Oleic Acid Nanoparticles Against <i>Schistosoma Mansoni</i> Adult Worms
Category:
Micro- and nanoparticle Delivery
Presenters:
Priscileila Ferrari
Authors:
<b>P. C. Ferrari</b><sup>1</sup>, J. Mioduski<sup>1</sup>, R. D. Santos<sup>1</sup>, B. Justus<sup>1</sup>, J. P. Paula<sup>1</sup>, R. N. Oliveira<sup>1</sup>, S. A. P. Corrêa<sup>2</sup>, S. M. Allegretti<sup>2</sup>; <sup>1</sup>Ponta Grossa State Univ., Ponta Grossa, Brazil, <sup>2</sup>Campinas State Univ., Campinas, Brazil
Institutions:
Ponta Grossa State University
In Vitro Interaction Between Macrophages And Cubosomes For Oral Vaccine Delivery Imaged By Coherent Anti-stokes Raman Scattering (CARS) And Automated Microscopy
Category:
Delivery of Proteins, Peptides, and Vaccines
Presenters:
Line Hagner Nielsen
Authors:
<b>L. Hagner Nielsen</b><sup>1</sup>, M. T. Bargholz<sup>1</sup>, J. Saarinen<sup>2</sup>, C. von Halling Laier<sup>1</sup>, O. Ilchenko<sup>1</sup>, A. O. Isomäki<sup>3</sup>, A. Boisen<sup>1</sup>, C. Strachan<sup>2</sup>; <sup>1</sup>Dept. of Micro and Nanotechnology, Technical Univ. of Denmark, Kgs. Lyngby, Denmark, <sup>2</sup>Div. of Pharmaceutical Chemistry and Technology, Univ. of Helsinki,, Helsinki, Finland, <sup>3</sup>Biomedicum Imaging Unit, Univ. of Helsinki, Helsinki, Finland
Institutions:
Department of Micro and Nanotechnology, Technical University of Denmark
In Vitro Skin Permeation Studies used in the NDA and ANDA Submissions to the US-FDA for the Approval of Transdermal Delivery Systems</i><b></b>
Category:
Topical and Transdermal Delivery
Presenters:
Kaushalkumar Dave
Authors:
<b>K. Dave</b><sup>1</sup>, C. Wu<sup>2</sup>, A. Dorantes<sup>1</sup>, O. Anand<sup>1</sup>, P. Seo<sup>1</sup>; <sup>1</sup>U.S. Food and Drug Admin., Silver Spring, MD, <sup>2</sup>Univ. of California San Fracisco, San Francisco, CA
Institutions:
U.S. Food and Drug Administration
In Vitro To In Vivo Extrapolation (ivive) Of Itraconazole Precipitation Using A Biphasic Dissolution Test And Mechanistic Absorption Model
Category:
Oral Delivery for Food and Pharma
Presenters:
Jim Mullin
Authors:
<b>J. M. Mullin</b>, K. Szeto, V. Lukacova, M. B. Bolger; Simulations Plus, Lancaster, CA
Institutions:
Simulations Plus
In Vitro/in Vivo Evaluations Of Nose-to-Brain Drug Delivery Platform Technology In Monkeys
Category:
Regional Delivery
Presenters:
Yusuke Torikai
Authors:
<b>Y. Torikai</b>, Y. Sonoda, S. Sakoda, A. Kyuno, H. Mishima, S. Fukakusa, K. Sasaki, S. Haruta; SNBL, Ltd., Kagoshima, Japan
Institutions:
SNBL, Ltd.
In Vivo Bone Marrow Nucleic Acid Delivery Systems for Therapeutic Targeting of Multiple Myeloma-Microenvironment Interactions
Category:
Nucleic Acid Delivery
Presenters:
Michael Mitchell
Authors:
<b>M. J. Mitchell</b>; Univ. of Pennsylvania, Philadelphia, PA
Institutions:
University of Pennsylvania
In Vivo Lipid Nanocapsules-mediated Glucagon Like Peptide 2 Secretion
Category:
Oral Delivery for Food and Pharma
Presenters:
Yining Xu
Authors:
<b>Y. Xu</b>, D. Carradori, M. Alhouayek, G. G. Muccioli, P. Cani, V. Préat, A. Beloqui; Université catholique de Louvain, Brussels, Belgium
Institutions:
Université catholique de Louvain
In Vivo Reduction of Halcinonide Toxicity Encapsulated into Polymeric Lipid-Core Nanoparticles
Category:
Micro- and nanoparticle Delivery
Presenters:
Priscileila Ferrari
Authors:
<b>P. C. Ferrari</b>, C. E. Lopes, L. Lipinski, P. V. Farago; Ponta Grossa State Univ., Ponta Grossa, Brazil
Institutions:
Ponta Grossa State University
In Vivo Release of Liquid Polymer-Based Sustained Release Formulations of Celecoxib
Category:
Parenteral Controlled Release
Presenters:
Gert Hendriks
Authors:
P. van Midwoud<sup>1</sup>, <b>G. Hendriks</b><sup>2</sup>, E. de Boef<sup>1</sup>, R. Meijboom<sup>1</sup>, M. van Dijk<sup>1</sup>, N. Korthagen<sup>3</sup>, H. Weinans<sup>3</sup>; <sup>1</sup>InGell Labs, Groningen, Netherlands, <sup>2</sup>InnoCore Pharmaceuticals, Groningen, Netherlands, <sup>3</sup>Univ. of Utrecht, Utrecht, Netherlands
Institutions:
InnoCore Pharmaceuticals
In Vivo Wnt Inhibition in Lung Tumors via Oral Administration of Cyclodextrin-Small Molecule Complexes
Category:
Oral Delivery for Food and Pharma
Presenters:
Pedro Guimaraes
Authors:
<b>P. P. G. Guimaraes</b>, M. Tan, M. Mitchell, R. Langer; MIT, Cambridge, MA
Institutions:
MIT
Incorporation Of Taxane Prodrugs Improves The Therapeutic Efficacy Of Lipid Nanoparticles Containing Androgen Receptor siRNA
Category:
Nucleic Acid Delivery
Presenters:
Roy van der Meel
Authors:
<b>R. van der Meel</b><sup>1</sup>, S. Chen<sup>2</sup>, J. Zaifman<sup>1</sup>, J. A. Kulkarni<sup>1</sup>, J. Quick<sup>1</sup>, Y. K. Tam<sup>3</sup>, M. A. Ciufolini<sup>1</sup>, M. B. Bally<sup>4</sup>, R. M. Schiffelers<sup>5</sup>, Y. Y. C. Tam<sup>2</sup>, P. R. Cullis<sup>1</sup>; <sup>1</sup>Univ. of British Columbia, Vancouver, BC, Canada, <sup>2</sup>Integrated Nanotherapeutics, Vancouver, BC, Canada, <sup>3</sup>Acuitas Therapeutics, Vancouver, BC, Canada, <sup>4</sup>British Columbia Cancer Agency, Vancouver, BC, Canada, <sup>5</sup>Univ. Med. Ctr. Utrecht, Utrecht, Netherlands
Institutions:
University of British Columbia
Increasing <i>Pseudomonas Aeruginosa</i> Biofilm Eradicating Efficacy By Dual-delivery Of A Novel Alkylquinolone Quorum Sensing Inhibitor And Tobramycin Using Squalenyl Hydrogen Sulfate Nanocarrier
Category:
Micro- and nanoparticle Delivery
Presenters:
Khiet Ho
Authors:
<b>K. D. Ho</b><sup>1</sup>, D. Didier<sup>2</sup>, X. Murgia<sup>1</sup>, A. G. H. d. M. Martins<sup>1</sup>, C. De Rossi<sup>1</sup>, M. Koch<sup>3</sup>, M. Empting<sup>1</sup>, R. W. Hartmann<sup>1</sup>, B. Loretz<sup>1</sup>, P. Couvreur<sup>2</sup>, C. M. Lehr<sup>1</sup>; <sup>1</sup>Helmholtz Inst. for Pharmaceutical Res. Saarland (HIPS), Saarbrücken, Germany, <sup>2</sup>Faculté de Pharmacie, Inst. Galien Paris Sud, Univ.́ Paris Sud, Université Paris-Saclay, UMR CNRS 8612, Paris, France, <sup>3</sup>Leibniz Inst. for New Materials (INM), Saarbrücken, Germany
Institutions:
Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)
Inhalable Star-polypeptide-siRNA Polyplexes As Novel Therapeutic Platforms For Respiratory Diseases
Category:
Nucleic Acid Delivery
Presenters:
Alice McCloskey
Authors:
<b>A. McCloskey</b><sup>1</sup>, L. Sweeney<sup>2</sup>, R. Gaul<sup>1</sup>, R. Murphy<sup>1</sup>, J. Ramsey<sup>1</sup>, A. Heise<sup>1</sup>, R. MacLoughlin<sup>2</sup>, S-A. Cryan<sup>1</sup>; <sup>1</sup>Royal Coll. of Surgeons in Ireland, Dublin, Ireland, <sup>2</sup>Aerogen, Galway, Ireland
Institutions:
Royal College of Surgeons in Ireland
Inhalation Treatment Of Lung Cancer: The Influence Of Composition, Size And Shape Of Nanocarriers On Their Lung Accumulation And Retention
Category:
Micro- and nanoparticle Delivery
Presenters:
olga garbuzenko
Authors:
<b>o. garbuzenko</b><sup>1</sup>, G. Mainelis<sup>2</sup>, O. Taratula<sup>3</sup>, T. Minko<sup>1</sup>; <sup>1</sup>Rutgers State Univ., Piscataway, NJ, <sup>2</sup>Rutgers State Univ., New Brunswick, NJ, <sup>3</sup>Oregon State Univ., Portland, OR
Institutions:
Rutgers State University