Annual Meeting Archives

2018

Long-term Delivery Of Biologics: A Hybrid System Approach Using Composite Nanoformulation
Category:
Delivery of Proteins, Peptides, and Vaccines
Presenters:
Vibhuti Agrahari
Authors:
<b>V. Agrahari</b><sup>1</sup>, V. Agrahari<sup>2</sup>, A. K. Mitra<sup>2</sup>; <sup>1</sup>Bernard J Dunn Sch. of Pharmacy, Shenandoah Univ., Winchester, VA, <sup>2</sup>Sch. of Pharmacy, Univ. of Missouri-Kansas City, Kansas City, MO
Institutions:
Bernard J Dunn School of Pharmacy, Shenandoah University
Long-term Local Chemotherapy For Malignant Glioblastoma Brain Cancer Using Controlled Release From Multi-layered Membrane Wafers Made Of Coaxially Electrospun Fibers
Category:
Regional Delivery
Presenters:
Daewoo Han
Authors:
<b>D. Han</b><sup>1</sup>, R. Serra<sup>2</sup>, N. Gorelick<sup>2</sup>, H. Brem<sup>2</sup>, B. Tyler<sup>2</sup>, A. Steckl<sup>1</sup>; <sup>1</sup>Univ. of Cincinnati, Cincinnati, OH, <sup>2</sup>Johns Hopkins Univ., Baltimore, MD
Institutions:
University of Cincinnati
Long-term Oral Administration Of Exendin-4 To Control Type 2 Diabetic Condition In Rat Using Simple Nanocarrier
Category:
Oral Delivery for Food and Pharma
Presenters:
Kenichi Suzuki
Authors:
<b>K. Suzuki</b>; Univ. of Utah, Salt Lake City, UT
Institutions:
University of Utah
Long-term Stability Test Of Insulin For Implantable Devices
Category:
Delivery of Proteins, Peptides, and Vaccines
Presenters:
Jia He
Authors:
<b>J. He</b><sup>1</sup>, E. Renard<sup>2</sup>, P. Lord<sup>3</sup>, D. J. Burgess<sup>1</sup>; <sup>1</sup>Univ. of Connecticut, Storrs, CT, <sup>2</sup>Montpellier Univ. Hosp., Montpellier, France, <sup>3</sup>PhysioLogic Devices Inc., Alpine, CA
Institutions:
University of Connecticut
Low Volume Production Of Nanoparticles That Are Effective Transfection Systems In Ipsc-derived Cells, Immune Cells And Other Primary Cell Cultures
Category:
Nucleic Acid Delivery
Presenters:
Andrea Armstead
Authors:
A. Brown, C. Cayabyab, R. DeSouza, T. Fernandez, G. Tharmarajah, A. Thomas, S. Clarke, <b>A. Armstead</b>, P. Johnson, E. Ramsay; Precision NanoSystems Inc., Vancouver, BC, Canada
Institutions:
Precision NanoSystems Inc.
Lysosome-responsive And Activated Rapeseed Protein-based Polymer-drug Nanocomposite Targets Multiple Intracellular Organelles In Metastatic Cancer Cells
Category:
Micro- and nanoparticle Delivery
Presenters:
Rui Zhang
Authors:
Z. Wang<sup>1</sup>, <b>R. X. Zhang</b><sup>2</sup>, T. Zhang<sup>3</sup>, C. He<sup>3</sup>, R. He<sup>4</sup>, X. Ju<sup>1</sup>, X. Y. Wu<sup>3</sup>; <sup>1</sup>Sch. of Food Sci. and Technology, Jiangnan Univ., Wuxi, China, <sup>2</sup>Sch. of Life Sci., Northwestern Polytechnical Univ., Xi'an, China, <sup>3</sup>Leslie Dan Faculty of Pharmacy, Univ. of Toronto, Toronto, ON, Canada, <sup>4</sup>Nanjing Univ. of Finance and Economics, Nanjing, China
Institutions:
School of Life Sciences, Northwestern Polytechnical University
Machine Learning Processes to Develop Targeted Nanomedicines
Category:
Micro- and nanoparticle Delivery
Presenters:
Daniel Heller
Authors:
<b>D. A. Heller</b>, Y. Shamay, J. Shah, M. Isik, J. D. Chodera; Mem. Sloan Kettering Cancer Ctr., New York, NY
Institutions:
Memorial Sloan Kettering Cancer Center
Mannan-based Drug Delivery System Targeted To Sentinel Lymph Nodes
Category:
Micro- and nanoparticle Delivery
Presenters:
Marketa Jiratova
Authors:
<b>M. Jiratova</b><sup>1</sup>, A. Galisova<sup>2</sup>, M. Rabyk<sup>3</sup>, E. Sticova<sup>4</sup>, M. Hruby<sup>3</sup>, D. Jirak<sup>2</sup>; <sup>1</sup>Inst. for Clinical and Experimental Med.; Dept. of Physiology, Faculty of Sci., Charles Univ., Prague, Czech Republic, <sup>2</sup>Inst. for Clinical and Experimental Med.; Inst. of Biophysics and Informatics, 1st Med. Faculty, Charles Univ., Prague, Czech Republic, <sup>3</sup>Inst. of Macromolecular Chemistry of the Academy of Sci. of the Czech Republic, Prague, Czech Republic, <sup>4</sup>Inst. for Clinical and Experimental Med., Prague, Czech Republic
Institutions:
Institute for Clinical and Experimental Medicine; Department of Physiology, Faculty of Science, Charles University
Mannose Receptor Targeted Inhalable Nanoliposomal Formulations for Improved Therapy of Tuberculosis
Category:
Micro- and nanoparticle Delivery
Presenters:
Isha Naik
Authors:
<b>I. V. Naik</b><sup>1</sup>, R. Jain<sup>1</sup>, A. Ugarkar<sup>1</sup>, S. Vaidya<sup>2</sup>, E. Coutinho<sup>1</sup>, M. Menon<sup>1</sup>; <sup>1</sup>Bombay Coll. of Pharmacy, Mumbai, India, <sup>2</sup>Dept. of Clinical Pathology, Haffkine Inst. for Training, Res. &Testing, Parel, Mumbai, India
Institutions:
Bombay College of Pharmacy
Manufacture of Verteporfin Loaded Liposomes using a Scalable Microfluidic Platform
Category:
Micro- and nanoparticle Delivery
Presenters:
Peter Johnson
Authors:
A. Brown<sup>1</sup>, I. Captain<sup>1</sup>, S. M. Garg<sup>1</sup>, E. Ouellet<sup>1</sup>, B. Versteeg<sup>1</sup>, J. Singh<sup>1</sup>, M. Ma<sup>1</sup>, A. W. Wild<sup>2</sup>, <b>P. Johnson</b><sup>1</sup>, A. Armstead<sup>1</sup>, E. C. Ramsay<sup>1</sup>, A. Thomas<sup>1</sup>; <sup>1</sup>Precision NanoSystems Inc., Vancouver, BC, Canada, <sup>2</sup>Precision NanoSystems Inc,, Vancouver, BC, Canada
Institutions:
Precision NanoSystems Inc.
Massive Oral Absorption Of Intact Nanoparticle Mediated By Bile Acid Transporter And Proposed Transport Pathways
Category:
Oral Delivery for Food and Pharma
Presenters:
Kyoung Sub Kim
Authors:
<b>K. Kim</b>, Y. Bae; Univ. of Utah, Salt lake city, UT
Institutions:
University of Utah
Material Development And Characterisation Of A Functionalised Biomaterial To Support Transplanted Islet Viability.
Category:
Manufacture, Characterization, Measurement, and Stability
Presenters:
Liam McDonough
Authors:
<b>L. McDonough</b><sup>1</sup>, E. B. Dolan<sup>2</sup>, L. Burke<sup>1</sup>, G. P. Duffy<sup>2</sup>, H. Kelly<sup>1</sup>; <sup>1</sup>Royal Coll. of Surgeons in Ireland, Dublin, Ireland, <sup>2</sup>Natl. Univ. of Ireland Galway, Galway, Ireland
Institutions:
Royal College of Surgeons in Ireland
Mathematical Kinetics Model Explaining The Intracellular Uptake And Elimination Processes: <i>Impact On The Photodynamic Potential Of Photosensitizer-loaded Nanoparticles</i>
Category:
Micro- and nanoparticle Delivery
Presenters:
Aya Sebak
Authors:
<b>A. Sebak</b><sup>1</sup>, I. Gomaa<sup>2</sup>, A. ElMeshad<sup>3</sup>, M. AbdelKader<sup>4</sup>; <sup>1</sup>German Univ. in Cairo, Cairo, Egypt, <sup>2</sup>Nile Univ., Cairo, Egypt, <sup>3</sup>Cairo Univ., Cairo, Egypt, <sup>4</sup>Natl. Inst. for Laser Enhanced Sci. (NILES), Cairo, Egypt
Institutions:
German University in Cairo
Mathematical Modeling Guides Design Of Controlled Release Formulation For Sustained Pest Control
Category:
Encapsulation for Industrial Applications
Presenters:
Min Zhao
Authors:
<b>M. Zhao</b><sup>1</sup>, M. Rushton<sup>2</sup>, R. Boucher<sup>2</sup>, M. Kalinowski<sup>3</sup>, K. Harris<sup>3</sup>, L. Liu<sup>2</sup>, J. Babcock<sup>2</sup>, M. Olson<sup>2</sup>; <sup>1</sup>The Dow Chemical Company, Collegeville, PA, <sup>2</sup>Dow AgroSci., Indianapolis, IN, <sup>3</sup>The Dow Chemical Company, Midland, MI
Institutions:
The Dow Chemical Company
Matrix Stiffness Differentially Regulates Cell Uptake Of Nanoparticles In 2d Cultures Two Breast Cancer Cells
Category:
Manufacture, Characterization, Measurement, and Stability
Presenters:
Yao Fu
Authors:
Y. Wang, <b>Y. Fu</b>; Sichuan Univ., Chengdu, China
Institutions:
Sichuan University
Measurement Of API-polymer Interactions Via Fluorescent-molecular Rotor As Preclinical Screening Tool
Category:
Manufacture, Characterization, Measurement, and Stability
Presenters:
Carolin Auch
Authors:
<b>C. Auch</b><sup>1</sup>, M. Harms<sup>1</sup>, K. Mäder<sup>2</sup>; <sup>1</sup>Merck KGaA, Darmstadt, Germany, <sup>2</sup>Martin Luther Univ. Halle-Wittenberg, Halle/Saale, Germany
Institutions:
Merck KGaA
Mechanistic Modeling And Prediction Of The Effect Of Food On Oral Drug Absorption
Category:
Oral Delivery for Food and Pharma
Presenters:
Oljora Rezhdo
Authors:
<b>O. Rezhdo</b>, L. S. Speciner, R. L. Carrier; Northeastern Univ., Boston, MA
Institutions:
Northeastern University
Meeting Unmet Needs: The Sustained-Release Of Protein And Peptide Drugs
Category:
Delivery of Proteins, Peptides, and Vaccines
Presenters:
Burkhardt Laufer
Authors:
<b>B. Laufer</b>; Ascendis Pharma GmbH, Heidelberg, Germany
Institutions:
Ascendis Pharma GmbH
Melt Solubilization and Controlled Cooling Enabled In Situ Micronization
Category:
Micro- and nanoparticle Delivery
Presenters:
Rashmi Nair
Authors:
<b>R. Nair</b>; Dr. Reddy's lab., Hyderabd, India
Institutions:
Dr. Reddy's lab.
Metabolomic Study Of Polymer-doxorubicin Conjugates In Breast Cancer Models<b></b>
Category:
Parenteral Controlled Release
Presenters:
Maria Vicent
Authors:
A. Armiñan<sup>1</sup>, M. Palomino-Schätzlein<sup>2</sup>, C. Deladriere<sup>1</sup>, J. J. Arroyo-Crespo<sup>1</sup>, S. Vicente-Ruiz<sup>1</sup>, <b>M. J. Vicent</b><sup>1</sup>, A. Pineda-Lucena<sup>3</sup>; <sup>1</sup>Polymer Therapeutics Lab. Centro Investigacion Principe Felipe, Valencia, Spain, <sup>2</sup>Joint Res. Unit in Clinical Metabolomics. Centro Investigacion Principe Felipe, Valencia, Spain, <sup>3</sup>Drug Discovery Unit, Inst. de Investigación Sanitaria La Fe, Valencia, Spain, Valencia, Spain
Institutions:
Polymer Therapeutics Lab. Centro Investigacion Principe Felipe
Micelle Stability Varies According to Human Biologic Fluid Identity
Category:
Manufacture, Characterization, Measurement, and Stability
Presenters:
Timothy Langridge
Authors:
<b>T. D. Langridge</b>, R. A. Gemeinhart; Univ. of Illinois BPS, Chicago, IL
Institutions:
University of Illinois BPS
Micro Fabricated Devices For Oral Drug Delivery
Category:
Oral Delivery for Food and Pharma
Presenters:
Line Nielsen
Authors:
<b>L. H. Nielsen</b><sup>1</sup>, A. Müllertz<sup>2</sup>, C. Mazzoni<sup>1</sup>, C. von Halling Laier<sup>1</sup>, F. Tentor<sup>1</sup>, P. Marizza<sup>1</sup>, R. S. Petersen<sup>1</sup>, S. Strindberg Andersen<sup>2</sup>, S. S. Keller<sup>1</sup>, T. Rades<sup>2</sup>, Z. Abid<sup>1</sup>, A. Boisen<sup>1</sup>; <sup>1</sup>Dept. of Micro and Nanotechnology, Technical Univ. of Denmark, Kgs. Lyngby, Denmark, <sup>2</sup>Dept. of Pharmacy, Univ. of Copenhagen, Copenhagen, Denmark
Institutions:
Department of Micro and Nanotechnology, Technical University of Denmark
Microencapsulation Of Turmeric Curcuminoids (<i>Curcuma Longa</i>) In Chitosan-gum Arabic Coacervates
Category:
Encapsulation for Industrial Applications
Presenters:
HUGO ESPINOSA-ANDREWS
Authors:
<b>H. ESPINOSA-ANDREWS</b>, K. E. Enríquez-Ramírez; CIATEJ, GUADALAJARA, Mexico
Institutions:
CIATEJ
Microfluidic Protein Loading Into Liposomal Delivery Systems For Oral Vaccination: Optimisation Of Key Production Parameters
Category:
Delivery of Proteins, Peptides, and Vaccines
Presenters:
Neil Forbes
Authors:
<b>N. Forbes</b>; Univ. of Strathclyde, Glasgow, United Kingdom
Institutions:
University of Strathclyde
Microfluidics-based Manufacture Of PLGA Nanoparticles And Microparticles For Use As Drug Delivery Vehicles.
Category:
Micro- and nanoparticle Delivery
Presenters:
Shyam Garg
Authors:
<b>S. M. Garg</b>, A. Thomas, T. J. Leaver, A. W. Wild, S. Clarke, P. Johnson, A. Armstead, E. C. Ramsay; Precision NanoSystems Inc., Vancouver, BC, Canada
Institutions:
Precision NanoSystems Inc.