Annual Meeting Archives

2018

Novel Combination Therapy Of Liposomal Dry Powder Inhaler Systems For Amelioration Of Chronic Obstructive Pulmonary Disease: Formulation Development, Characterization And <i>In-vivo </i>Evaluation.
Category:
Micro- and nanoparticle Delivery
Presenters:
Smita Khare
Authors:
<b>S. A. Khare</b><sup>1</sup>, M. D. Menon<sup>1</sup>, S. Sule<sup>2</sup>; <sup>1</sup>Bombay Coll. of Pharmacy, Mumbai, India, <sup>2</sup>Inhalation Product consultant, Preston, United Kingdom
Institutions:
Bombay College of Pharmacy
Novel Glucosylceramide Synthase Inhibitor Based Prodrug Copolymer Micelles for Delivery of Doxorubicin
Category:
Micro- and nanoparticle Delivery
Presenters:
Jieni Xu
Authors:
<b>J. Xu</b>, J. Sun, Y. Huang, S. Li; Univ. of Pittsburgh, Pittsburgh, PA
Institutions:
University of Pittsburgh
Novel Hollow Microneedle Can Deliver Large Volume For Intradermal Vaccination.
Category:
Topical and Transdermal Delivery
Presenters:
YOSHIHIRO KODAMA
Authors:
<b>Y. KODAMA</b><sup>1</sup>, I. Takase<sup>1</sup>, S. Naito<sup>2</sup>; <sup>1</sup>TOPPAN PRINTING Co., LTD., Saitama, Japan, <sup>2</sup>Natl. Inst. of Infectious Diseases, Tokyo, Japan
Institutions:
TOPPAN PRINTING Co., LTD.
Novel Hollow Pegylated Encapsulin Nanoparticles For The Incorporation Of Hydrophilic Compounds
Category:
Micro- and nanoparticle Delivery
Presenters:
Seiichi Sonotaki
Authors:
<b>S. Sonotaki</b>, T. Takami, K. Noguchi, M. Yohda, Y. Murakami; Tokyo Univ. of Agriculture and Technology, Tokyo, Japan
Institutions:
Tokyo University of Agriculture and Technology
Novel Methotrexate Conjugated Pectin Nanoparticles Containing Fluoxetine as Chemosensitizer for Colon-targeted Delivery
Category:
Oral Delivery for Food and Pharma
Presenters:
Kinjal Parikh
Authors:
<b>K. J. Parikh</b>, B. Patel, K. K. Sawant; The M S Univ. of Baroda, Vadodara, India
Institutions:
The M S University of Baroda
Novel Oligoethyleneglycol-based Dense Hydroxyl-terminated Dendrimer Peneterates Impaired Blood Brain/retinal Barrier And Targets Neuroinflammation
Category:
Micro- and nanoparticle Delivery
Presenters:
Rishi Sharma
Authors:
<b>R. Sharma</b>, A. Sharma, Z. Zhang, S. Kambhampati, K. Liaw, J. E. Porterfield, L. DeRidder, K. Lin, S. Kannan, R. M. Kannan; Johns Hopkins Sch. of Med., Baltimore, MD
Institutions:
Johns Hopkins School of Medicine
Novel Peptides Designed By A Rational Approach Show Higher Binding Affinity Towards CD13 Than The Known CNGRC(C1-C5) Peptide Ligand
Category:
Delivery of Proteins, Peptides, and Vaccines
Presenters:
Xiaoling Li
Authors:
M. Uddin, <b>X. Li</b>, H. Joo, J. Tsai, L. Wrischnik, B. Jasti; Univ. of the Pacific, Stockton, CA
Institutions:
University of the Pacific
Novel pH-triggered, Fluorescent, Mesoporous Silica Nanoparticles For Potential Theranostic Applications In Cancer Intervention
Category:
Micro- and nanoparticle Delivery
Presenters:
Lara Freidus
Authors:
<b>L. G. Freidus</b>, P. Pradeep, P. Kumar, T. Marimuthu, Y. E. Choonara, V. Pillay; Univ. of the Witwatersrand, Johannesburg, South Africa
Institutions:
University of the Witwatersrand
Novel Porous Plga Microparticles Formed By "one-step" Emulsification For Pulmonary Drug Delivery
Category:
Micro- and nanoparticle Delivery
Presenters:
Shinnosuke Nishimura
Authors:
<b>S. Nishimura</b>, T. Takami, Y. Murakami; Tokyo Univ. of Agriculture and Technology, Tokyo, Japan
Institutions:
Tokyo University of Agriculture and Technology
Nucleic Acid Carrier Optimization By Bioinspired Chemical Evolution
Presenters:
Ernst Wagner
Authors:
<b>E. Wagner</b>; LMU Univ., Munich, Germany
Institutions:
LMU University
Nucleic Acid-based Systemic Tumor-targeted Nanoparticles By Rolling Circle Replication For Direct Cell Detection And Gene Delivery
Category:
Micro- and nanoparticle Delivery
Presenters:
Sangwoo Han
Authors:
<b>S. Han</b>, J. Lee; Univ. of Seoul, Seoul, Korea, Republic of
Institutions:
University of Seoul
Obtaining Targeted Release Of Viable Freeze-dried Probiotic Strains By Granulation, Extrusion And Fluid Bed Coating
Category:
Oral Delivery for Food and Pharma
Presenters:
Natashia Larsen
Authors:
<b>N. M. Y. Larsen</b>, A. Caglayan, I. Caglayan, D. Bar-Shalom, A. Müllertz; Univ. of Copenhagen, Copenhagen, Denmark
Institutions:
University of Copenhagen
Ocular Diabetic Theranosis Using Smart Contact Lens
Category:
Delivery Science in Cosmetics, Personal Care, and Household Products
Presenters:
Sei Kwang Hahn
Authors:
<b>S. Hahn</b>, D. Keum; POSTECH, Pohang, Korea, Republic of
Institutions:
POSTECH
Ocular Pharmacokinetics Of A Dexamethasone-eluting Contact Lens
Category:
Regional Delivery
Presenters:
Joseph Ciolino
Authors:
<b>J. B. Ciolino</b><sup>1</sup>, B. Salvador-Culla<sup>1</sup>, L. C. Bengani<sup>2</sup>, R. Tulsan<sup>2</sup>, A. E. Ross<sup>2</sup>, D. S. Kohane<sup>3</sup>; <sup>1</sup>Massachusetts Eye & Ear/Harvard Med. Sch., Boston, MA, <sup>2</sup>Schepens Eye Res. Inst. at Massachusettes Eye & Ear/Harvard Med. Sch., Boston, MA, <sup>3</sup>Boston Children's Hosp./Harvard Med. Sch., Boston, MA
Institutions:
Massachusetts Eye & Ear/Harvard Medical School
On The Formation and Morphology of Lipid Nanoparticles Containing Ionizable Cationic Lipids And siRNA
Category:
Micro- and nanoparticle Delivery
Presenters:
Jayesh Kulkarni
Authors:
<b>J. A. Kulkarni</b><sup>1</sup>, M. M. Darjuan<sup>1</sup>, J. E. Mercer<sup>2</sup>, S. Chen<sup>3</sup>, I. V. Zhigaltsev<sup>1</sup>, R. van der Meel<sup>4</sup>, J. Thewalt<sup>2</sup>, Y. C. Tam<sup>3</sup>, P. R. Cullis<sup>1</sup>; <sup>1</sup>Univ. of British Columbia, Vancouver, BC, Canada, <sup>2</sup>Simon Fraser Univ., Vancouver, BC, Canada, <sup>3</sup>Integrated Nanotherapeutics, Vancouver, BC, Canada, <sup>4</sup>Utrecht Univ. Med. Ctr., Utretcht, Netherlands
Institutions:
University of British Columbia
Optimization Of <i>Alpinia Galanga</i> Oil Loaded Self-nanoemulsifying Drug Delivery System (SNEDDS) Using Design Of Experiments For Fish Anesthesia
Category:
Micro- and nanoparticle Delivery
Presenters:
Nattakanwadee Khumpirapang
Authors:
<b>N. Khumpirapang</b><sup>1</sup>, A. Müllertz<sup>2</sup>, T. Rades<sup>2</sup>, S. Okonogi<sup>3</sup>; <sup>1</sup>Interdisciplinary Program in NanoSci. and Nanotechnology, Graduate Sch., Chiang Mai, Thailand, <sup>2</sup>Faculty of Hlth.and Med. Sci., Univ. of Copenhagen, Copenhagen, Denmark, <sup>3</sup>Faculty of Pharmacy, Chiang Mai Univ., Chiang Mai, Thailand
Institutions:
Interdisciplinary Program in Nanoscience and Nanotechnology, Graduate School
Optimization Of A Polymeric Nanoparticle Formulation For Bioresponsive Release Of Doxorubicin
Category:
Micro- and nanoparticle Delivery
Presenters:
Laura Gonzalez-Fajardo
Authors:
<b>L. Gonzalez-Fajardo</b>, L. H. Mahajan, D. Ndaya, R. M. Kasi, X. Lu; Univ. of Connecticut, Storrs, CT
Institutions:
University of Connecticut
Optimization Of Formulation And 3D Geometric Variables Affecting In Vitro Performance Of Modified-release Tablets Manufactured By 3D Printing Method
Category:
Manufacture, Characterization, Measurement, and Stability
Presenters:
Alaadin Alayoubi
Authors:
<b>A. Alayoubi</b>, A. S. Zidan, S. Asfari, C. N. Cruz, M. Ashraf; U.S FDA, Silver Spring, MD
Institutions:
U.S FDA
Optimization Of Lipid Nanoparticles For Intramuscular Administration Of Messenger Ribonucleic Acid (mRNA) Vaccines<b></b>
Category:
Nucleic Acid Delivery
Presenters:
Kimberly Hassett
Authors:
<b>K. Hassett</b>, K. Benenato, E. Jacquinet, J. Milano, K. Hughes, V. Presnyak, A. Lee, A. Woods, O. Yuzhakov, S. Himansu, A. Lynn, I. McFadyen, J. Senn, M. Stanton, Ö. Almarsson, G. Ciaramella, L. Brito; Moderna Therapeutics, Cambridge, MA
Institutions:
Moderna Therapeutics
Optimization Of Nanoparticle Processing To Improve Bioavailability Based On Quality By Design Approach
Category:
Micro- and nanoparticle Delivery
Presenters:
Sang Yeob Park
Authors:
<b>S. Park</b><sup>1</sup>, Z. Kang<sup>2</sup>, Y. Jin<sup>2</sup>, J. Park<sup>2</sup>, H. Lim<sup>1</sup>, J. Lee<sup>1</sup>, S-W. Lee<sup>1</sup>, M-H. Seo<sup>1</sup>, M. Kim<sup>3</sup>, S. Jeong<sup>4</sup>; <sup>1</sup>Samyang Biopharmaceuticals Corp., Seongnam, Korea, Republic of, <sup>2</sup>Bio-Synectics, Inc., Seoul, Korea, Republic of, <sup>3</sup>Pusan Natl. Univ., Pusan, Korea, Republic of, <sup>4</sup>Dongguk Univ., Goyang, Korea, Republic of
Institutions:
Samyang Biopharmaceuticals Corp.
Oral Peptide Delivery: The Potential Of Combining Nanoparticle Constructs With Permeation Enhancers
Presenters:
David Brayden
Authors:
<b>D. Brayden</b><sup>1</sup>, F. McCartney<sup>2</sup>, S. Sladek<sup>2</sup>, D. Hristov<sup>2</sup>; <sup>1</sup><sup>2</sup>Univ. Coll. Dublin, Dublin, Ireland
Oral Permeability And Pharmacokinetics Of A Pediatric Formulation For The Treatment Of Cerebral Palsy
Category:
Oral Delivery for Food and Pharma
Presenters:
Venkata Yellepeddi
Authors:
<b>V. K. Yellepeddi</b><sup>1</sup>, R. Mohammadipur<sup>1</sup>, C. Sayre<sup>2</sup>, S. Khambampati<sup>3</sup>, M. Mishra<sup>3</sup>, R. Kannan<sup>3</sup>, H. Ghandehari<sup>1</sup>; <sup>1</sup>Univ. of Utah, Salt Lake City, UT, <sup>2</sup>Roseman Univ. of Hlth.Sci., Salt Lake City, UT, <sup>3</sup>Johns Hopkins Univ., Baltimore, MD
Institutions:
University of Utah
Orally Active Site-directed Polymer-drug Complexes For Modulating Gut Innate Immune System To Prevent/treat Ulcerative Colitis
Category:
Oral Delivery for Food and Pharma
Presenters:
Siddharth Kesharwani
Authors:
<b>S. S. Kesharwani</b><sup>1</sup>, R. Ahmad<sup>2</sup>, M. A. Bakkari<sup>1</sup>, M. K. Rajput<sup>1</sup>, R. Dachineni<sup>1</sup>, C. K. Valiveti<sup>1</sup>, G. Bhat<sup>1</sup>, A. B. Singh<sup>2</sup>, H. Tummala<sup>1</sup>; <sup>1</sup>Dept. of Pharmaceutical Sci., Coll. of Pharmacy & Allied Hlth.Professions, South Dakota State Univ., Brookings, SD, <sup>2</sup>Dept. of Biochemistry and Molecular Biology, Univ. of Nebraska Med. Ctr., Omaha, NE
Institutions:
Department of Pharmaceutical Sciences, College of Pharmacy & Allied Health Professions, South Dakota State University
Orally Delivered Butyrate-functionalized Nanovehicles To Overcome Multiple Barriers And Insight Into “Easy Entry, Hard Exit” Of Active Targeting System In Intestinal Absorption
Category:
Micro- and nanoparticle Delivery
Presenters:
Lei Wu
Authors:
<b>L. Wu</b>, Y. Huang; Sichuan Univ., Chengdu, China
Institutions:
Sichuan University
Organic-inorganic Hybrid Core-shell Particles Made From Biodegradable Coacervate Droplets For Bone Tissue Engineering
Category:
Micro- and nanoparticle Delivery
Presenters:
Syuuhei Komatsu
Authors:
<b>S. Komatsu</b><sup>1</sup>, Y. Ikedo<sup>1</sup>, T-A. Asoh<sup>2</sup>, R. Ishihara<sup>1</sup>, A. Kikuchi<sup>1</sup>; <sup>1</sup>Tokyo Univ. of Sci., Tokyo, Japan, <sup>2</sup>Osaka Univ., Osaka, Japan
Institutions:
Tokyo University of Science