Annual Meeting Archives

2018

Standardization Of Assessment Of Syringeability And Injectability Of Abuse Deterrent Formulations Through Time-dependent Force-distance Profile
Category:
Manufacture, Characterization, Measurement, and Stability
Presenters:
Xin Feng
Authors:
<b>X. Feng</b><sup>1</sup>, V. Balajee<sup>2</sup>, J. Leissa<sup>2</sup>, M. Ashraf<sup>1</sup>, C. N. Cruz<sup>1</sup>, X. Xu<sup>1</sup>; <sup>1</sup>U.S. Food and Drug Admin., Silver Spring, MD, <sup>2</sup>Univ. of Maryland, College Park, MD
Institutions:
U.S. Food and Drug Administration
Stat3 Decoy Oligonucleotide-carrying Microbubbles With Pulsed Ultrasound For Enhanced Therapeutic Effect In Head And Neck Tumors
Category:
Nucleic Acid Delivery
Presenters:
Thiruganesh Ramasamy
Authors:
<b>T. Ramasamy</b>; Univ. of Pittsburgh, Pittsburgh, Pittsburgh, PA
Institutions:
University of Pittsburgh, Pittsburgh
Statistical Assessment of Dissolution Profile Comparison - Multivariate Analysis (MVA)
Category:
Manufacture, Characterization, Measurement, and Stability
Presenters:
Hugo Almeida
Authors:
<b>H. Almeida</b>, P. Barrocas, T. Vasconcelos, J. Teixeira, P. Soares-da-Silva, R. Lima; Bial Portela & Cª S. A., Coronado, Portugal
Institutions:
Bial Portela & Cª S. A.
Stimuli-sensitive Theranostic Nanoparticles For Imaging-guided Targeted Drug Delivery: Characterization and Trafficking Patterns In An Animal Model
Category:
Micro- and nanoparticle Delivery
Presenters:
Ousama Rachid
Authors:
<b>O. Rachid</b><sup>1</sup>, Y. Haik<sup>2</sup>, R. Abdi<sup>3</sup>; <sup>1</sup>Coll. of Pharmacy, Qatar Univ., Doha, Qatar, <sup>2</sup>Hamada Bin Khalifa Univ., Doha, Qatar, <sup>3</sup>Harvard Med. Sch., Boston, MA
Institutions:
College of Pharmacy, Qatar University
Stochastic Lattice-based Model For Modelling Macromolecules Release From Degradable Hydrogel
Category:
Delivery of Proteins, Peptides, and Vaccines
Presenters:
Ghodsiehsadat Jahanmir
Authors:
<b>G. Jahanmir</b>, C. LAU, Y. CHAU; Hong Kong Univ. of Sci. and technology, Hong Kong, Hong Kong
Institutions:
Hong Kong university of science and technology
Studies On The Protective Effect Of Ginger Extract And Ginger Nanoparticle On Paracetamol Toxicity In Rats
Category:
Oral Delivery for Food and Pharma
Presenters:
Alaa Bakr
Authors:
<b>A. F. Bakr</b>, S. S. AbdEl-gayed, O. S. EL-Tawil, A. M. Bakeer; Cairo Univ., Cairo, Egypt
Institutions:
Cairo University
Study Of Cryoprotectants For Freeze-drying Of Polyelectrolyte Complexes Based On Chitosan
Category:
Manufacture, Characterization, Measurement, and Stability
Presenters:
Sandra Agostini
Authors:
<b>S. B. N. Agostini</b>, V. L. S. Machado, V. M. L. Naves, G. R. Pereira, F. C. Carvalho; Federal Univ. of Alfenas, Alfenas, Brazil
Institutions:
Federal University of Alfenas
Study On The Construction Of LncRNA MEG3 Nanoparticles Mediated By EpCAM And Its Effect On Prostate Cancer Cells
Category:
Micro- and nanoparticle Delivery
Presenters:
Quangang Zhu
Authors:
<b>Q. Zhu</b>, Z. Chen, D. An, j. Ding; Shanghai Dermatology Hosp.，Tongji Univ., Shanghai, China
Institutions:
Shanghai Dermatology Hospital，Tongji University
Study On The Construction Of Multi-walled Carbon Nanotubes Modified By Anti-psma Aptamer And Its Effect On Prostate Cancer Diagnosis
Category:
Micro- and nanoparticle Delivery
Presenters:
Zhongjian Chen
Authors:
<b>Z. Chen</b>, Q. Zhu, D. An; Shanghai Dermatology Hosp.，Tongji Univ., Shanghai, China
Institutions:
Shanghai Dermatology Hospital，Tongji University
Study on Tumor Combination Therapy Using Sialic Scid Derivative Modified Liposomes Loaded with Tumstatin T7 Peptide And Doxorubicin<b></b>
Category:
Micro- and nanoparticle Delivery
Presenters:
Yanzhi Song
Authors:
<b>Y. Song</b>, T. Li, M. Liu, Y. Xiong, R. Feng, C. Wang, Y. Deng; Shenyang Pharmaceutical Univ., Shenyang, China
Institutions:
Shenyang Pharmaceutical University
Sub-chronic Toxicity Of Silica Nanoparticles In Female And Male Balb/c Mice
Category:
Micro- and nanoparticle Delivery
Presenters:
Raziye Mohammadpour
Authors:
<b>R. Mohammadpour</b>, M. Yazdimamaghani, D. Cheney, J. Jedrzkiewicz, H. Ghandehari; Univ. of Utah, Salt Lake City, UT
Institutions:
University of Utah
Subcutaneous Elastin-like Polypeptides (ELP) Loaded With Rapamycin Alleviate Dacryoadenitis In A Model Of Sjögren’s Syndrome
Category:
Delivery of Proteins, Peptides, and Vaccines
Presenters:
Changrim Lee
Authors:
<b>C. Lee</b><sup>1</sup>, H. Guo<sup>1</sup>, W. Klinngam<sup>1</sup>, S. Janga<sup>2</sup>, F. Yarber<sup>2</sup>, M. Edman<sup>2</sup>, S. Peddi<sup>1</sup>, S. F. Hamm-Alvarez<sup>2</sup>, J. A. MacKay<sup>1</sup>; <sup>1</sup>Dept. of Pharmacology and Pharmaceutical Sci., Sch. of Pharmacy, Univ. of Southern California, Los Angeles, CA, <sup>2</sup>Dept. of Ophthalmology, Roski Eye Inst. and Keck Sch. of Med., Univ. of Southern California, Los Angeles, CA
Institutions:
Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California
SuperparamagneticIronoxidenanoparticles(SPIONs)formagneticresonanceimaging ofmacrophagesingliomas:atthe interfacebetween nanomedicineandinnateimmunity
Presenters:
Dmitri Simberg
Authors:
<b>D. Simberg</b>, H. Caulkins, P. Hong, N. J. Serkova; Univ. of Colorado Anschutz Med. Campus, Aurora, CO
Institutions:
University of Colorado Anschutz Medical Campus
Supersaturated Silica-lipid Hybrid Formulations - Improving The Oral Delivery Of Poorly Water-soluble Drugs
Category:
Oral Delivery for Food and Pharma
Presenters:
Hayley Schultz
Authors:
<b>H. B. Schultz</b>, N. Thomas, C. A. Prestidge; Univ. of South Australia, Adelaide, Australia
Institutions:
University of South Australia
Supramolecular Nanotube Hydrogels for Enhanced Tumor Penetrating and Local Brain Tumor Treatment
Category:
Parenteral Controlled Release
Presenters:
Feihu Wang
Authors:
<b>F. Wang</b>, H. Su, R. Lin, R. Chakroun, H. Cui; Dept. of Chemical and Biomolecular Engineering & Inst. for NanoBiotechnology (INBT), Johns Hopkins Univ., Baltimore, MD
Institutions:
Department of Chemical and Biomolecular Engineering & Institute for NanoBiotechnology (INBT), Johns Hopkins University
Surface Characterisation And Advanced Imaging Of Initial Gel Formation And Swelling Of Hypromellose Compacts
Category:
Manufacture, Characterization, Measurement, and Stability
Presenters:
Adam Ward
Authors:
<b>A. Ward</b><sup>1</sup>, K. Asare-Addo<sup>1</sup>, K. Walton<sup>1</sup>, B. Conway<sup>1</sup>, P. Timmins<sup>1</sup>, W. Kaialy<sup>2</sup>; <sup>1</sup>Univ. of Huddersfield, Huddersfield, United Kingdom, <sup>2</sup>Univ. of Wolverhampton, Wolverhampton, United Kingdom
Institutions:
University of Huddersfield
Surface De-pegylation Controls Nanoparticle-Mediated Small Interfering Ribonucleic Acid Delivery In Vitro And In Vivo
Category:
Nucleic Acid Delivery
Presenters:
Zameer Bharwani
Authors:
<b>Z. Bharwani</b><sup>1</sup>, W. Tao<sup>1</sup>, X. Zhu<sup>2</sup>, J. Shi<sup>1</sup>, O. Farokhzad<sup>1</sup>; <sup>1</sup>Ctr. for Nanomedicine and Dept. of Anesthesiology, Brigham and Women’s Hosp., Harvard Med. Sch., Boston, MA, <sup>2</sup>Natl. Shanghai Ctr. for New Drug Safety Evaluation and Res., Shanghai, China
Institutions:
Center for Nanomedicine and Department of Anesthesiology, Brigham and Women’s Hospital, Harvard Medical School
Surface Modified Nanoparticles for Reduced Systemic Clearance and Enhanced Tumor Targeting Through Hitchhiking on Red Blood Cells
Category:
Micro- and nanoparticle Delivery
Presenters:
Siddharth Kesharwani
Authors:
<b>S. S. Kesharwani</b><sup>1</sup>, P. Muley<sup>1</sup>, A. Ukidve<sup>2</sup>, G. Bhat<sup>1</sup>, S. Mitragotri<sup>2</sup>, H. Tummala<sup>1</sup>; <sup>1</sup>Dept. of Pharmaceutical Sci., Coll. of Pharmacy & Allied Hlth.Professions, South Dakota State Univ., Brookings, SD, <sup>2</sup>John A. Paulson Sch. of Engineering and Applied Sci., Harvard Univ., Cambridge, MA
Institutions:
Department of Pharmaceutical Sciences, College of Pharmacy & Allied Health Professions, South Dakota State University
Surfactant Effects On Biodegradable Nanoparticle Uptake Across The Blood-Brain Barrier And Penetration Within The Brain: Implications For Drug Delivery To The Injured Newborn Brain
Category:
Micro- and nanoparticle Delivery
Presenters:
Andrea Joseph
Authors:
<b>A. Joseph</b>, K. Corry, T. Wood, S. Juul, P. Parikh, E. Nance; Univ. of Washington, Seattle, WA
Institutions:
University of Washington
Sustained Release Of Peptide Drug From Biodegradable Temperature-responsive Injectable Hydrogels Exhibiting Irreversible Gelation
Category:
Parenteral Controlled Release
Presenters:
Yuta Yoshizaki
Authors:
<b>Y. Yoshizaki</b>, K. Takata, H. Takai, Y. Yoshida, T. Nagata, A. Kuzuya, Y. Ohya; Kansai Univ., Suita, Japan
Institutions:
Kansai University
Sustained Release Of VEGF From Biodegradable SynBiosys® Microspheres
Category:
Delivery of Proteins, Peptides, and Vaccines
Presenters:
Thanh Nguyen
Authors:
A. Duarte<sup>1</sup>, K. C. Scheiner<sup>2</sup>, R. J. Kok<sup>2</sup>, G. Hendriks<sup>1</sup>, R. Steendam<sup>1</sup>, <b>T. Nguyen</b><sup>1</sup>; <sup>1</sup>InnoCore Pharmaceuticals, Groningen, Netherlands, <sup>2</sup>Utrecht Univ., Groningen, Netherlands
Institutions:
InnoCore Pharmaceuticals
Sustained-release Of Proteins From Self-reporting Porous Silicon Microparticles
Category:
Delivery of Proteins, Peptides, and Vaccines
Presenters:
Joanna Wang
Authors:
<b>J. Wang</b><sup>1</sup>, T. Kumeria<sup>2</sup>, M. T. Bezem<sup>3</sup>, J. Wang<sup>4</sup>, M. J. Sailor<sup>1</sup>; <sup>1</sup>Univ. of California at San Diego, San Diego, CA, <sup>2</sup>Univ. of Queensland, Queensland, Australia, <sup>3</sup>Univ. of Bergen, Bergen, Norway, <sup>4</sup>Henan Polytechnic Univ., Jiaozuo, China
Institutions:
University of California at San Diego
Sustaining Tissue Viability In Severe Wounds Through Controlled Release Of Proteins From Swellable Polymers
Category:
Delivery of Proteins, Peptides, and Vaccines
Presenters:
Anthony Duong
Authors:
<b>A. Duong</b>, J. Lilly, J. Boyce, E. Edwards; Battelle Mem. Inst., Columbus, OH
Institutions:
Battelle Memorial Institute
Synchronizing The Release Rates Of Salicylate And Indomethacin From A Degradable Chitosan Hydrogel And Its Optimization By Definitive Screening Design
Category:
Regional Delivery
Presenters:
Racheli Sharon Gabbay
Authors:
<b>R. Sharon Gabbay</b><sup>1</sup>, A. Rubinstein<sup>1</sup>, R. S. Kenett<sup>2</sup>; <sup>1</sup>The Hebrew Univ. of Jerusalem, Jerusalem, Israel, <sup>2</sup>The KPA Group, 25 Hataasia Street, Raanana 43100, Israel
Institutions:
The Hebrew University of Jerusalem
Synthesis and Evaluation of Tumor Hypoxia-Targeting Albumin Nanoparticles for Treating Triple Negative Breast Cancer
Category:
Delivery of Proteins, Peptides, and Vaccines
Presenters:
Ketki Bhise
Authors:
K. Tatiparti<sup>1</sup>, <b>K. Bhise</b><sup>1</sup>, K. Gawde<sup>1</sup>, G. Nabil<sup>2</sup>, H. El banna<sup>3</sup>, S. Sau<sup>1</sup>, A. K. Iyer<sup>4</sup>; <sup>1</sup>Use‐inspired Biomaterials & Integrated Nano Delivery (U‐BiND) Systems Lab., Dept. of Pharmaceutical Sci., Wayne State Univ., Detroit, MI, <sup>2</sup>Use‐inspired Biomaterials & Integrated Nano Delivery (U‐BiND) Systems Lab., Dept. of Pharmaceutical Sci., Wayne State Univ.. 2Dept. of Pharmacology, Faculty of Vet. Med., Cairo Univ., Giza, Egypt, Detroit, MI, <sup>3</sup>Dept. of Pharmacology, Faculty of Vet. Med., Cairo Univ., Giza, Egypt., Detroit, MI, <sup>4</sup>Use‐inspired Biomaterials & Integrated Nano Delivery (U‐BiND) Systems Lab., Dept. of Pharmaceutical Sci., Wayne State Univ.; Molecular Imaging Program, Karmanos Cancer Inst., Detroit, Michigan, USA, Detroit, MI
Institutions:
Use‐inspired Biomaterials & Integrated Nano Delivery (U‐BiND) Systems Lab., Dept. of Pharmaceutical Sci., Wayne State University