Annual Meeting Archives

2016

Investigating the Interior of Lipid Nanoparticles for mRNA Delivery by Surface Enhanced DNP-NMR
Category:
Oligonucleotide Delivery: New Applications and Opportunities
Authors:
S. SCHANTZ (1), J. Viger-Gravel (2), A. Schantz (1), A. Rossini (3), A. Pinon (2), L. Emsley (2)
Institutions:
(1) AstraZeneca R&D Mölndal, Sweden; (2) EPFL Lausanne, Switzerland; (3) Iowa state University, U.S.A.
Investigating the physical stability of a spray-dried pulmonary drug delivery system
Category:
Local Drug Delivery
Authors:
L. CHIA (1), A. Zeitler (1), W. Ng (2), R. Tan (2), G. Moggridge (1)
Institutions:
(1) University of Cambridge, United Kingdom; (2) Institute of Chemical and Engineering Sciences, A*STAR, Singapore
Investigating tumor cell specificity of a nanoparticle with a surface-converting coating by multimodal imaging
Category:
Integration of Imaging and Drug Delivery
Authors:
F. FAY (1), L. Hansen (2), Z. Fayad (3), C. Perez-medina (3), W. Mulder (3)
Institutions:
(1) Translational and Molecular Imaging Institute, Icahn School Icahn School of Medicine at Mount Sinai, U.S.A.; (2) Interdisciplinary Nanoscience Center, Aarhus University, Denmark; (3) Translational and Molecular Imaging Institute, Icahn School of Medic
Investigation of a fully bioresorbable scaffold with coated eluted drug
Category:
Manufacture, Characterization, Stability, and Regulatory Aspects
Authors:
T. MAHMOOD (1), C. Roberts (1), K. Al-Lamee (2), M. Alexnder (1), N. Bullett (2)
Institutions:
(1) University of Nottingham, United Kingdom; (2) Arterius Ltd, United Kingdom
Investigation of novel biomaterials based nanoformulations of anti-TNF monoclonal antibody to treat inflammation in an in-vitro cell culture model
Category:
Local Drug Delivery
Authors:
R. PABARI (1)
Institutions:
(1) Royal College of Surgeons in Ireland, Ireland
Jet dispensing as a high throughput method for rapid screening and manufacturing of cocrystals
Category:
Manufacture, Characterization, Stability, and Regulatory Aspects
Authors:
D. DOUROUMIS (1), N. Scoutaris (1)
Institutions:
(1) University of Greenwich, United Kingdom
Junction opener protein increases nanoparticle accumulation in solid tumors in a size-dependent manner
Category:
Physical Oncology: Modulating Tumor Microenvironment for Drug Delivery
Authors:
C. WANG (1), R. Yumul (1), A. Lieber (1), S. Pun (1)
Institutions:
(1) University of Washington, U.S.A.
Kolliphor® HS 15 Micelles for the Delivery of Hydrophobic Neuroprotective Agent CNB001
Category:
Overcoming Biological Barriers in Drug Delivery
Authors:
Z. MERCHANT (1), K. Taylor (1), G. Buckton (1), S. Somavarapu (1)
Institutions:
(1) UNIVERSITY COLLEGE LONDON, United Kingdom
Latent, Heat-Activated ROMP Curing Polyester Thermosets for Encapsulation
Category:
New Processes, New Materials, New Products
Authors:
R. BAUMGARTNER (1), K. Ryba (1), Z. Song (1), R. Wang (1), J. Cheng (1)
Institutions:
(1) University of Illinois at Urbana-Champaign, U.S.A.
Light-Triggered Tumor Targeted Delivery of Anticancer Therapeutics Using ROS-sensitive Polymeric Micelles
Category:
Local Drug Delivery
Authors:
G. SEAH (1), J. Kim (1), J. Yu (1), Y. Nam (1)
Institutions:
(1) Korea Advanced Institute of Science and Technology (KAIST), South Korea
Lipid-like Nanoparticles for mRNA Delivery in vivo
Category:
Overcoming Biological Barriers in Drug Delivery
Authors:
Y. DONG (1), B. Li (1), X. Luo (1), B. Deng (1), J. Wang (1), D. McComb (1), Y. Shi (2), K. Gaensler (2), X. Tan (3), A. Dunn (4), B. Kerlin (4)
Institutions:
(1) The Ohio State University, U.S.A.; (2) University of California-San Francisco, U.S.A.; (3) Tsinghua University, China; (4) Nationwide Children’s Hospital, U.S.A.
Liposomal Bortezomib for Targeted Proteasome Inhibition in Cancer
Category:
Local Drug Delivery
Authors:
M. FENS (1), A. Deshantri (1), B. Metselaar (2), R. Schiffelers (1)
Institutions:
(1) University Medical Center Utrecht, Netherlands; (2) Enceladus pharmaceuticals, Netherlands
Liposomal Delivery of miRNA against Herpes Simplex Virus 1
Category:
Oligonucleotide Delivery: New Applications and Opportunities
Authors:
G. GOLOMB (1), A. Giterman (1), O. Feldman (1), A. Dagan (1), A. Kühbacher (2), S. Rupp (2)
Institutions:
(1) The Hebrew University of Jerusalem, Israel; (2) Fraunhofer Institute, Germany
Liposomal Doxorubicin for bile acid transporters-mediated oral absorption
Category:
Oral Delivery
Authors:
H. HWANG (1), C. Lee (2), K. Na (2), Y. Bae (1)
Institutions:
(1) University of Utah, U.S.A.; (2) The Catholic University of Korea, Korea
Liposomes and skin barrier: getting through and restoring function
Category:
Overcoming Biological Barriers in Drug Delivery
Authors:
E. LIMA (1)
Institutions:
(1) Universidade Federal de Goiás, Brazil
Liposomes Reloaded: A novel strategy for loading “unloadable” drugs into stealth liposomes
Category:
Parenteral Systemic Delivery of Biopharmaceuticals: Overcoming Product Development and Regulatory Challenges
Authors:
S. SUR (1), K. Kinzler (2), S. zhou (2), B. Vogelstein (2)
Institutions:
(1) Johns Hopkins Medical Institutions, baltimore, MD, U.S.A.; (2) Ludwig Center and Howard Hughes Medical Institute at the Johns Hopkins Kimmel Cancer Center, U.S.A.
Liver-specific delivery of a novel DNA/RNA heteroduplex oligonucleotide via enteral routes produced by the combination of a-tocopherol conjugation and permeation enhancers.
Category:
Oligonucleotide Delivery: New Applications and Opportunities
Authors:
C. WATANABE (1), Y. Cheng (1), A. Watari (2), M. Kondoh (2), M. Murakami (1), T. Yokota (3), K. Yagi (2), K. Nishina (3), Y. Matsumoto (4), K. Toh (5), K. Yoshida-Tanaka (3), S. Obika (2), K. Kataoka (6), K. Miyata (6)
Institutions:
(1) Osaka Ohtani University, Japan; (2) Osaka University, Japan; (3) Tokyo Medical and Dental University, Japan; (4) Tokyo Univesity, Japan; (5) Tokyo University, Japan; (6) The University of Tokyo, Japan
Local delivery of atorvastatin with enhanced solubility for the treatment of periodontal disease
Category:
Local Drug Delivery
Authors:
S. SENEL (1), A. OZDOGAN (2), G. AKCA (3)
Institutions:
(1) Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Technology, Turkey; (2) Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Technology , Turkey; (3) Gazi University, Faculty of Dentistry, Department of Medic
Local image-guided drug delivery across the Blood-Brain barrier (BBB) using focused ultrasound
Category:
Local Drug Delivery
Authors:
K. HYNYNEN (1)
Institutions:
(1) University of Toronto, Canada
Long circulating Ferritin Nanocage with 'Protein cloud'
Category:
Thinking Outside the Box Delivery Technologies: Nanocarriers from Nature
Authors:
N. LEE (1), E. Lee (1), K. Nam (1), Y. Byun (2), I. Kim (1)
Institutions:
(1) Korea Institute of Science and Technology, South Korea; (2) Seoul National University, South Korea
Low temperature hot melt extrusion processibility of ethylene vinyl acetate copolymers as pharmaceutical controlled release excipients
Category:
Manufacture, Characterization, Stability, and Regulatory Aspects
Authors:
B. ZHANG (1), C. Schneider (1), J. Haley (1), D. Hair (1)
Institutions:
(1) Celanese, U.S.A.
Lung targeted montelukast loaded PLGA nano-in-microparticles for treatment of asthma
Category:
Overcoming Biological Barriers in Drug Delivery
Authors:
R. OSMAN (1), R. Abdelgawad (1), G. Awad (1), N. Mortada (1)
Institutions:
(1) Faculty of Pharmacy, Ain Shams University, Egypt
Lung targeted moxifloxacin loaded vesicular delivery systems
Category:
Overcoming Biological Barriers in Drug Delivery
Authors:
R. OSMAN (1), A. Hamed (1), S. Mansour (1)
Institutions:
(1) Faculty of Pharmacy, Ain Shams University, Egypt
Magnetic field activated lipid–polymer hybrid nanoparticles for stimuli-responsive drug release
Category:
Integration of Imaging and Drug Delivery
Authors:
S. KONG (1), L. Zhang (2)
Institutions:
(1) California Baptist University, U.S.A.; (2) University of Califronia, San Diego, U.S.A.
Magnetic Nanocomplex-Mediated Gene Delivery on Mesenchymal Stem Cells and Applications on Glioma Treatment
Category:
Oligonucleotide Delivery: New Applications and Opportunities
Authors:
R. HUANG (1), Y. Lin (1), S. Lin (1), C. Chang (1)
Institutions:
(1) Department of Biomedical Engineering & Environmental Sciences, National Tsing Hua University, Taiwan