Oral Delivery of Peptides, Oligonucleotides and Proteins-Virtual Symposium

Supported by:

**All Information is Subject to Change**

Wednesday, November 29th, 2023

*All times listed in EST

Click Here to View Speaker Bios

9:00 AM to 9:15 AM

Welcome, Logistics, and Introduction

On behalf of CRS - Symposium Co-Chairs:

Dr. Filippos Kesisoglou, MSc, PhD

Merck, USA

Dr. Liping Zhou, PhD

AstraZeneca, USA

Dr. Manuel Sanchez-Felix, PhD

Halozyme, USA




9:15 AM to 10:45 AM

Session 1A:  Biopharmaceutical Challenges, Discovery Chemistry and Preclinical Screens/Studies

Overview of the Challenges and Achievements in Oral Administration of Peptides

Dr. David Brayden, Ph.D.

University College Dublin, Ireland

45 minutes



A Biopharmaceutics Perspective on Oral Delivery of Peptides,
Proteins & Oligonucleotides

Dr. Manuel Sanchez-Felix, PhD

Halozyme, USA

45 minutes

10:45 AM to 11:00 AM


11:00 AM to 12:30 PM

Session 1A (Contd.):  Biopharmaceutical Challenges, Discovery Chemistry and Preclinical Screens/Studies

Regional Delivery of MAB and Screens

Dr. Vipul Yadav

Intract Pharma, UK

30 minutes


In-vitro Cellular Assays 

Rebecca Carrier

Northeastern University, USA

30 minutes


Permeability Mechanism

Dr. Karthik Nagapudi, PhD

Genentech, USA

30 minutes


12:30 PM to 1:00 PM

Q&A Session

1:00 PM to 1:15 PM

Welcome, Introduction, and Logistics - Co-Chair Liping Zhou

1:15 PM to 2:45 PM

Session 1B: Formulation/Screens and Ingestible Devices

Formulation Peptide Screening

Dr. John Gleeson, PhD

Merck, USA

30 minutes


HT Screening Formulation Design

Thomas Von Erlach, PhD

VivTex, USA

30 minutes


Ingestible Oral Devices

Dr. Sharat Singh, PhD

Biora, USA

30 minutes


2:45 PM to 3:15 PM

Q&A Session

3:15 to 3:30 PM

Closing Remarks - Co-Chair Liping Zhou


Thursday, November 30th, 2023

*All times listed in EST

9:00 AM  to 9:15 AM

Welcome, Introduction, and Logistics - Co-Chair Manuel Sanchez-Felix 

9:15 AM  to 10:45 AM

Session 2A: Clinical Translation

Overview of Peptide Oral Delivery 

Dr. Puneet Tyagi, PhD

AstraZeneca, USA

30 minutes


Oral Oligonucleotide Delivery

Dr. Nigel Davies, PhD

AstraZeneca, SE

30 minutes


Oral Monoclonal Antibody Delivery – A Reality Check

Prof. Randall Mrsny, PhD

University of Bath, UK

30 minutes


10:45 AM to 11:00 AM


11:00 AM to 12:15 PM

Session 2A (Contd.): Clinical Translation

Oral Semaglutide: From Concept to Reality

Dr. Stephen T. Buckley, PhD

Novo Nordisk, USA

30 minutes


MK-0616: An Oral Macrocyclic Peptide Inhibitor of PCSK9

Dr. Douglas Johns, PhD, FAHA

Merck, USA

30 minutes


Symposium Summary and Overview

Dr. Manuel Sanchez-Felix


15 minutes


12:15 PM to 12:45 PM

Q&A Session

12:45 PM to 1:00 PM

Closing Remarks - Co-Chair Manuel Sanchez-Felix