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Fluorescent Imaging of COX-2 in Pathological Tissues by Fluorocoxib A-Loaded Nanoparticles

Authors:

Md. Jashim Uddin, Thomas A. Werfel, Brenda C. Crews, Mukesh K. Gupta, Taylor E. Kavanaugh, Philip J. Kingsley, Kelli Boyd, Lawrence J. Marnett, Craig L. Duvall

Introduction Overexpression of cyclooxegenase-2 (COX-2) is a hallmark of inflammation and an early event in carcinogenesis and cancer progression.1,2 Because COX-2 is expressed in virtually all solid tumors, it represents an ideal biomarker with broad impact for the early clinical detection of…

Joint Australian and New Zealand CRS Workshop

Authors:

Nicole Bisset

On April 21 and 22, 2016, Monash Institute of Pharmaceutical Sciences (MIPS) in Melbourne hosted the 2016 Joint Annual Australian–New Zealand CRS Student Workshop Zach Houston finishes his presentation in front of the magnificent Sissons Mural at Monash Parkville campus.under the theme “Crossing…

Questioning the Rate-Limiting Drug Release and Absorption Mechanisms from an Intramuscular Long-Acting Injectable Prodrug Nano-/Microsuspension: The Effect of Local Macrophage Depletion

Authors:

Nicolas Darville, Marjolein van Heerden, Stefaan Rossenu, Guy Van den Mooter, Sandra De Jonghe, An Vermeulena

Introduction Long-acting injectable (LAI) (pro)drug nano-/microsuspensions—aqueous dispersions of pure (pro)drug nano-/microcrystals—have shown potential as a drug delivery strategy over the past decade and are now recognized as an attractive formulation option for poorly water-soluble drug…

Boston: City of Champions

Authors:

Medha Joshi

The 44th CRS annual meeting was held in Boston, Massachusetts, the “City of Champions.” Like the five-time Super Bowl champions, the New England Patriots, Boston has always been a champion of pharmaceutical innovation. In fact, Bloomberg Business ranked Massachusetts the #1 state for innovation…

Drug Delivery and Translational Research Update

Special Issue on Ocular Drug Delivery The issue contains articles by recognized global experts and researchers in the field of ophthalmic drug delivery, covering a broad spectrum of drug delivery topics including current challenges faced with regard to the ocular barriers presented and…

NZCRS Publication Ethics and Manuscript Writing Workshop

Authors:

Zimei Wu, Darren Svirskis, Dedeepya Uppalapati

David Grainger presents on how to write a good research paper.In June 2016, the New Zealand Local Chapter of the Controlled Release Society (CRS) hosted David W. Grainger (University of Utah, U.S.A.) for an educational workshop at the Faculty of Medical and Health Sciences, University of Auckland.…